Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P09738

- SODM_STRMU

UniProt

P09738 - SODM_STRMU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Superoxide dismutase [Mn/Fe]

Gene

sodA

Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarity, Fe2+By similarityNote: Binds 1 Mn(2+) or Fe(2+) ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi27 – 271Manganese or ironBy similarity
Metal bindingi81 – 811Manganese or ironBy similarity
Metal bindingi163 – 1631Manganese or ironBy similarity
Metal bindingi167 – 1671Manganese or ironBy similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Iron, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciSMUT210007:GC7Z-613-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn/Fe] (EC:1.15.1.1)
Gene namesi
Name:sodA
Synonyms:sod
Ordered Locus Names:SMU_629
OrganismiStreptococcus mutans serotype c (strain ATCC 700610 / UA159)
Taxonomic identifieri210007 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002512: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 203202Superoxide dismutase [Mn/Fe]PRO_0000160094Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi210007.SMU.629.

Structurei

3D structure databases

ProteinModelPortaliP09738.
SMRiP09738. Positions 5-199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0605.
KOiK04564.
OMAiTIFWQIM.
OrthoDBiEOG63NMNT.
PhylomeDBiP09738.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P09738-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAILLPDLPY AYDALEPYID AETMTLHHDK HHATYVANAN AALEKHPEIG
60 70 80 90 100
ENLEVLLADV EQIPADIRQS LINNGGGHLN HALFWELLSP EKTKVTAEVA
110 120 130 140 150
AAINEAFGSF DDFKAAFTAA ATTRFGSGWA WLVVDKEGKL EVTSTANQDT
160 170 180 190 200
PISQGLKPIL ALDVWEHAYY LNYRNVRPNY IKAFFEVINW NTVARLYAEA

LTK
Length:203
Mass (Da):22,626
Last modified:January 23, 2007 - v3
Checksum:iCC86C35928C415A6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti4 – 41L → T AA sequence (PubMed:3722201)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D01037 Genomic DNA. Translation: BAB86870.1.
AE014133 Genomic DNA. Translation: AAN58363.1.
PIRiA42710.
RefSeqiNP_721057.1. NC_004350.2.
YP_006489870.1. NC_018089.1.

Genome annotation databases

EnsemblBacteriaiAAN58363; AAN58363; SMU_629.
GeneIDi1029605.
13299631.
KEGGismu:SMU_629.
smut:SMUGS5_02755.
PATRICi19663445. VBIStrMut61772_0555.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D01037 Genomic DNA. Translation: BAB86870.1 .
AE014133 Genomic DNA. Translation: AAN58363.1 .
PIRi A42710.
RefSeqi NP_721057.1. NC_004350.2.
YP_006489870.1. NC_018089.1.

3D structure databases

ProteinModelPortali P09738.
SMRi P09738. Positions 5-199.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 210007.SMU.629.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN58363 ; AAN58363 ; SMU_629 .
GeneIDi 1029605.
13299631.
KEGGi smu:SMU_629.
smut:SMUGS5_02755.
PATRICi 19663445. VBIStrMut61772_0555.

Phylogenomic databases

eggNOGi COG0605.
KOi K04564.
OMAi TIFWQIM.
OrthoDBi EOG63NMNT.
PhylomeDBi P09738.

Enzyme and pathway databases

BioCyci SMUT210007:GC7Z-613-MONOMER.

Family and domain databases

InterProi IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view ]
PANTHERi PTHR11404. PTHR11404. 1 hit.
Pfami PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000349. SODismutase. 1 hit.
PRINTSi PR01703. MNSODISMTASE.
SUPFAMi SSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEi PS00088. SOD_MN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of Streptococcus mutans superoxide dismutase gene and isolation of insertion mutants."
    Nakayama K.
    J. Bacteriol. 174:4928-4934(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: GS-5.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700610 / UA159.
  3. "A Streptococcus mutans superoxide dismutase that is active with either manganese or iron as a cofactor."
    Martin M.E., Byers B.R., Olson M.O.J., Salin M.L., Arceneaux J.E.L., Tolbert C.
    J. Biol. Chem. 261:9361-9367(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-23.

Entry informationi

Entry nameiSODM_STRMU
AccessioniPrimary (citable) accession number: P09738
Secondary accession number(s): Q59791
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: January 23, 2007
Last modified: November 26, 2014
This is version 110 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3