P09678 (SODC_BRAOC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn]
EC=1.15.1.1

Gene names

Name:

SODCC

Organism

Brassica oleracea var. capitata (Cabbage)

Taxonomic identifier

3716 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Brassiceae › Brassica › Brassica oleracea

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit. Binds 1 zinc ion per subunit.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.1
	Chain	2 – 152	151	Superoxide dismutase [Cu-Zn]		PRO_0000164134
Sites
	Metal binding	45	1	Copper; catalytic
	Metal binding	47	1	Copper; catalytic
	Metal binding	62	1	Copper; catalytic
	Metal binding	62	1	Zinc; structural
	Metal binding	70	1	Zinc; structural
	Metal binding	79	1	Zinc; structural
	Metal binding	82	1	Zinc; structural
	Metal binding	119	1	Copper; catalytic
Amino acid modifications
	Disulfide bond	56 ↔ 145

Sequences

	Sequence		Length	Mass (Da)
	P09678 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: A2CBB3748D508CF3	FASTA	152	15,172
	10 20 30 40 50 60 MAKGVAVLNS SEGVKGTIFF THEGNGATTV TGTVSGLRPG LHGFHVHALG DNTNGCMSTG 70 80 90 100 110 120 PHFNPDGKTH GAPEDANRHA GDLGNIIVGD DGTATFTITD SQIPLSGPNS IVGRAIVVHA 130 140 150 DPDDLGKGGH ELSLSTGNAG GRVACGIIGL QG

References

[1]

"Primary structure of Cu-Zn superoxide dismutase of Brassica oleracea proves homology with corresponding enzymes of animals, fungi and prokaryotes." Steffens G.J., Michelson A.M., Otting F., Puget K., Strassburger W., Flohe L. Biol. Chem. Hoppe-Seyler 367:1007-1016(1986) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-152.

Cross-references

Sequence databases
PIR	DSRPZC. A25569.
3D structure databases
ProteinModelPortal	P09678.
SMR	P09678. Positions 1-152.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODC_BRAOC

Accession

Primary (citable) accession number: P09678

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program