Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P09647 (RNPC_PENCH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanyl-specific ribonuclease Pc

Short name=RNase Pc
EC=3.1.27.3
OrganismPenicillium chrysogenum (Penicillium notatum)
Taxonomic identifier5076 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex

Protein attributes

Sequence length102 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.

Sequence similarities

Belongs to the ribonuclease N1/T1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 102102Guanyl-specific ribonuclease Pc
PRO_0000137373

Sites

Active site381 By similarity
Active site561Proton acceptor By similarity
Active site901Proton donor By similarity

Amino acid modifications

Disulfide bond2 ↔ 10 By similarity
Disulfide bond6 ↔ 101 By similarity

Sequences

Sequence LengthMass (Da)Tools
P09647 [UniParc].

Last modified July 1, 1989. Version 1.
Checksum: 49D8947B267D5506

FASTA10210,745
        10         20         30         40         50         60 
ACAATCGSVC YTSSAISAAQ EAGYDLYSAN DDVSNYPHEY RNYEGFDFPV SGTYYEFPIL 

        70         80         90        100 
RSGAVYSGNS PGADRVVFNG NDQLAGVITH TGASGNNFVA CD 

« Hide

References

[1]"Express analysis of protein amino acid sequences. Primary structure of Penicillium chrysogenum 152A guanyl-specific ribonuclease."
Shlyapnikov S.V., Bezborodova S.I., Kulikov V.A., Yakovlev G.I.
FEBS Lett. 196:29-33(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Strain: 152A.

Cross-references

Sequence databases

PIRA23620.

3D structure databases

ProteinModelPortalP09647.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.10.450.30. 1 hit.
InterProIPR000026. Gua-sp_ribonuclease_N1/T1.
IPR016191. Ribonuclease/ribotoxin.
[Graphical view]
PfamPF00545. Ribonuclease. 1 hit.
[Graphical view]
SUPFAMSSF53933. SSF53933. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNPC_PENCH
AccessionPrimary (citable) accession number: P09647
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families