Reviewed, UniProtKB/Swiss-Prot P09637 (HXA5_SALSA)

Names and origin

Protein names

Recommended name:
    Homeobox protein Hox-A5
Alternative name(s):
    S12-B

Gene names

Name:

hoxa5

Organism

Salmo salar (Atlantic salmon)

Taxonomic identifier

8030 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Protacanthopterygii › Salmoniformes › Salmonidae › Salmoninae › Salmo

Protein attributes

Sequence length	78 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location	Nucleus.
Sequence similarities	Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Gene Ontology (GO)
Biological process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 78	›78	Homeobox protein Hox-A5		PRO_0000200065
Regions
	DNA binding	1 – 60	60	Homeobox
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P09637-1 [UniParc]. Last modified January 1, 1990. Version 2. Checksum: 828DEBDDF78AC820	FASTA	78	9,489
	10 20 30 40 50 60 GRGRGQTYTR YQTLELEKEF HFNRYLTRRR RIEMAHALCL SERQIKIWFQ NRRMKWKKDN 70 KLKSMSMAAA GGVGYHRP

References

[1]	"Molecular cloning and characterization of homeo-box-containing genes from Atlantic salmon." Fjose A., Molven A., Eiken H.G. Gene 62:141-152(1988) [PubMed: 2897318] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	M18904 Genomic DNA. Translation: AAA49560.1.
PIR	I51342.
3D structure databases
SMR	P09637. Positions 2-63.
ModBase	Search...
Phylogenomic databases
HOVERGEN	P09637.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_region. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
PROSITE	PS00032. ANTENNAPEDIA. Partial match. PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HXA5_SALSA

Accession

Primary (citable) accession number: P09637

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	January 1, 1990
Last modified:	November 24, 2009
This is version 64 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)