P09634 (HXA7_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Homeobox protein Hox-A7

Alternative name(s):
Homeobox protein Hox-1.1
Homeobox protein R5

Gene names

Name:	Hoxa7
Synonyms:	Hoxa-7

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	105 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location	Nucleus.
Sequence similarities	Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 105	›105	Homeobox protein Hox-A7		PRO_0000200073
Regions
	DNA binding	5 – 64	60	Homeobox
	Compositional bias	91 – 105	15	Glu-rich (acidic)
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P09634 [UniParc]. Last modified July 1, 1989. Version 1. Checksum: 106C1DF938F2864B	FASTA	105	12,552
	10 20 30 40 50 60 LGPDGKRGRQ TYTRYQTLEL EKEFHFNRYL TRRRAVEIAH ALCLTERQIK IWFQNRRMKW 70 80 90 100 KKEHKDESQA PTAVPEDAVP SVSTAADKAD EEEEEEEEEE EEEEE

References

[1]	"Cloning and expression of rat homeo-box-containing sequences." Falzon M., Sanderson N., Chung S.Y. Gene 54:23-32(1987) [PubMed: 2886401] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Sprague-Dawley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M16807 Genomic DNA. No translation available.
IPI	IPI01016307.
PIR	A27471.
UniGene	Rn.203714.
3D structure databases
ProteinModelPortal	P09634.
SMR	P09634. Positions 6-69.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
RGD	1587253. Hoxa7.
Phylogenomic databases
eggNOG	roNOG12504.
GeneTree	ENSGT00600000084133.
HOVERGEN	HBG006088.
InParanoid	P09634.
OrthoDB	EOG4W9J4Z.
Gene expression databases
ArrayExpress	P09634.
Genevestigator	P09634.
GermOnline	ENSRNOG00000006544. Rattus norvegicus.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_eu. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00032. ANTENNAPEDIA. Partial match. PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HXA7_RAT

Accession

Primary (citable) accession number: P09634

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	July 1, 1989
Last modified:	December 14, 2011
This is version 100 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program