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P09591 (EFTU_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tufA
Ordered Locus Names:PA4265
AND
Name:tufB
Ordered Locus Names:PA4277
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000091365

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding81 – 855GTP By similarity
Nucleotide binding136 – 1394GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
P09591 [UniParc].

Last modified December 8, 2000. Version 2.
Checksum: A019D5BF8EBAB942

FASTA39743,370
        10         20         30         40         50         60 
MAKEKFERNK PHVNVGTIGH VDHGKTTLTA ALTKVCSDTW GGSARAFDQI DNAPEEKARG 

        70         80         90        100        110        120 
ITINTSHVEY DSAVRHYAHV DCPGHADYVK NMITGAAQMD GAILVCSAAD GPMPQTREHI 

       130        140        150        160        170        180 
LLSRQVGVPY IVVFLNKADM VDDAELLELV EMEVRDLLNT YDFPGDDTPI IIGSALMALE 

       190        200        210        220        230        240 
GKDDNGIGVS AVQKLVETLD SYIPEPVRAI DQPFLMPIED VFSISGRGTV VTGRVERGII 

       250        260        270        280        290        300 
KVQEEVEIVG IKATTKTTCT GVEMFRKLLD EGRAGENVGI LLRGTKREDV ERGQVLAKPG 

       310        320        330        340        350        360 
TIKPHTKFEC EVYVLSKEEG GRHTPFFKGY RPQFYFRTTD VTGNCELPEG VEMVMPGDNI 

       370        380        390 
KMVVTLIAPI AMEDGLRFAI REGGRTVGAG VVAKIIE 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004091 Genomic DNA. Translation: AAG07653.1.
AE004091 Genomic DNA. Translation: AAG07665.1.
X07950 Genomic DNA. Translation: CAA30775.1.
PIRF83111.
S01222.
RefSeqNP_252955.1. NC_002516.2.
NP_252967.1. NC_002516.2.

3D structure databases

ProteinModelPortalP09591.
SMRP09591. Positions 11-397.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA4277.

Proteomic databases

PRIDEP09591.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG07653; AAG07653; PA4265.
AAG07665; AAG07665; PA4277.
GeneID881697.
881718.
KEGGpae:PA4265.
pae:PA4277.
PATRIC19843221. VBIPseAer58763_4466.

Organism-specific databases

PseudoCAPPA4265.
PA4277.

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMAISAPAAC.
OrthoDBEOG6R5C6X.
PhylomeDBP09591.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_PSEAE
AccessionPrimary (citable) accession number: P09591
Secondary accession number(s): Q9HWD3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: December 8, 2000
Last modified: July 9, 2014
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families