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Protein

Lysine/arginine/ornithine-binding periplasmic protein

Gene

argT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP (By similarity).By similarity

GO - Biological processi

  • cellular response to nitrogen starvation Source: EcoCyc
  • cellular response to starvation Source: EcoCyc
  • cellular response to zinc ion Source: EcoCyc
  • L-lysine transport Source: EcoCyc
  • ornithine transport Source: EcoCyc

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:ARGT-MONOMER

Protein family/group databases

TCDBi3.A.1.3.1 the atp-binding cassette (abc) superfamily
3.A.1.3.29 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine/arginine/ornithine-binding periplasmic protein
Short name:
LAO-binding protein
Gene namesi
Name:argT
Ordered Locus Names:b2310, JW2307
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10072 argT

Subcellular locationi

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 221 PublicationAdd BLAST22
ChainiPRO_000003174923 – 260Lysine/arginine/ornithine-binding periplasmic proteinAdd BLAST238

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi60 ↔ 67By similarity

Keywords - PTMi

Disulfide bond, Phosphoprotein

Proteomic databases

EPDiP09551
PaxDbiP09551
PRIDEiP09551

2D gel databases

SWISS-2DPAGEiP09551

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (HisP), two transmembrane proteins (HisM and HisQ) and a solute-binding protein (ArgT).By similarity

Protein-protein interaction databases

BioGridi4260525, 19 interactors
DIPiDIP-9148N
IntActiP09551, 1 interactor
STRINGi316385.ECDH10B_2472

Structurei

3D structure databases

ProteinModelPortaliP09551
SMRiP09551
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105E89 Bacteria
COG0834 LUCA
HOGENOMiHOG000031896
InParanoidiP09551
KOiK10013
OMAiLYPTSYH
PhylomeDBiP09551

Family and domain databases

InterProiView protein in InterPro
IPR005768 Lys_Arg_Orn-bd
IPR018313 SBP_3_CS
IPR001638 Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF00497 SBP_bac_3, 1 hit
SMARTiView protein in SMART
SM00062 PBPb, 1 hit
TIGRFAMsiTIGR01096 3A0103s03R, 1 hit
PROSITEiView protein in PROSITE
PS01039 SBP_BACTERIAL_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P09551-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKSILALSL LVGLSTAASS YAALPETVRI GTDTTYAPFS SKDAKGDFVG
60 70 80 90 100
FDIDLGNEMC KRMQVKCTWV ASDFDALIPS LKAKKIDAII SSLSITDKRQ
110 120 130 140 150
QEIAFSDKLY AADSRLIAAK GSPIQPTLDS LKGKHVGVLQ GSTQEAYANE
160 170 180 190 200
TWRSKGVDVV AYANQDLVYS DLAAGRLDAA LQDEVAASEG FLKQPAGKDF
210 220 230 240 250
AFAGSSVKDK KYFGDGTGVG LRKDDAELTA AFNKALGELR QDGTYDKMAK
260
KYFDFNVYGD
Length:260
Mass (Da):27,992
Last modified:July 15, 1998 - v3
Checksum:iE9BF1ECF0BB8A6FD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti23A → P in AAA23971 (PubMed:3040734).Curated1
Sequence conflicti86 – 87ID → ST (PubMed:3040734).Curated2
Sequence conflicti95I → V (PubMed:3040734).Curated1
Sequence conflicti200 – 201FA → SP in AAA85768 (Ref. 5) Curated2
Sequence conflicti213F → L in AAA85768 (Ref. 5) Curated1
Sequence conflicti237 – 239GEL → ACV in AAA85768 (Ref. 5) Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75370.1
AP009048 Genomic DNA Translation: BAA16156.1
M68935 Genomic DNA Translation: AAA23971.1
U47027 Genomic DNA Translation: AAA85768.1
PIRiD65003 JKECT
RefSeqiNP_416813.1, NC_000913.3
WP_000748271.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75370; AAC75370; b2310
BAA16156; BAA16156; BAA16156
GeneIDi949030
KEGGiecj:JW2307
eco:b2310
PATRICifig|1411691.4.peg.4424

Entry informationi

Entry nameiARGT_ECOLI
AccessioniPrimary (citable) accession number: P09551
Secondary accession number(s): P77476
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 15, 1998
Last modified: March 28, 2018
This is version 137 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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