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Protein

Triplex capsid protein 2

Gene

TRX2

Organism
Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.UniRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Triplex capsid protein 2UniRule annotation
Gene namesi
Name:TRX2UniRule annotation
Ordered Locus Names:41
OrganismiVaricella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
Taxonomic identifieri10338 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeVaricellovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000002602 Componenti: Genome

Subcellular locationi

  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001157301 – 316Triplex capsid protein 2Add BLAST316

Interactioni

Subunit structurei

Interacts with TRX1 and major capisd protein/MCP.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae TRX2 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG090000IF.

Family and domain databases

HAMAPiMF_04019. HSV_TRX2. 1 hit.
InterProiView protein in InterPro
IPR002690. Herpes_capsid_2.
PfamiView protein in Pfam
PF01802. Herpes_V23. 1 hit.

Sequencei

Sequence statusi: Complete.

P09291-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMPFEIEVL LPGELSPAET SALQKCEGKI ITFSTLRHRA SLVDIALSSY
60 70 80 90 100
YINGAPPDTL SLLEAYRMRF AAVITRVIPG KLLAHAIGVG TPTPGLFIQN
110 120 130 140 150
TSPVDLCNGD YICLLPPVFG SADSIRLDSV GLEIVFPLTI PQTLMREIIA
160 170 180 190 200
KVVARAVERT AAGAQILPHE VLRGADVICY NGRRYELETN LQHRDGSDAA
210 220 230 240 250
IRTLVLNLMF SINEGCLLLL ALIPTLLVQG AHDGYVNLLI QTANCVRETG
260 270 280 290 300
QLINIPPMPR IQDGHRRFPI YETISSWIST SSRLGDTLGT RAILRVCVFD
310
GPSTVHPGDR TAVIQV
Length:316
Mass (Da):34,389
Last modified:July 1, 1989 - v1
Checksum:i096BD7A66122442B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04370 Genomic DNA. Translation: CAA27924.1.
PIRiF27341. WZBE41.

Similar proteinsi

Entry informationi

Entry nameiTRX2_VZVD
AccessioniPrimary (citable) accession number: P09291
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: February 15, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families