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P09188

- PGK_PENCH

UniProt

P09188 - PGK_PENCH

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Protein

Phosphoglycerate kinase

Gene
PGKA, PGK
Organism
Penicillium chrysogenum (Penicillium notatum)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401Substrate By similarity
Binding sitei123 – 1231Substrate By similarity
Binding sitei170 – 1701Substrate By similarity
Binding sitei219 – 2191ATP By similarity
Binding sitei311 – 3111ATP; via carbonyl oxygen By similarity
Binding sitei342 – 3421ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi371 – 3744ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:PGKA
Synonyms:PGK
OrganismiPenicillium chrysogenum (Penicillium notatum)
Taxonomic identifieri5076 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 415415Phosphoglycerate kinaseUniRule annotationPRO_0000145884Add
BLAST

Proteomic databases

PRIDEiP09188.

Interactioni

Subunit structurei

Monomer.

Structurei

3D structure databases

ProteinModelPortaliP09188.
SMRiP09188. Positions 2-414.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate binding By similarity
Regioni64 – 674Substrate binding By similarity

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P09188-1 [UniParc]FASTAAdd to Basket

« Hide

MSLSNKLPVT DVDLKGKRVL IRVDFNVPLD ENENVTNPQR IVGALPTIKY    50
AIDNGRKAVV LMSHLGRPDG KVNPKYSLKP VVPVLEELLG KSVTFTEDCI 100
GPQTEETVNK ASDGQVILLE NLRFHAEEEG SSKDAEGKKV KADKADVDRS 150
ASLTALGDVY VNDAFGTAQR AHSSMVGVDL PQKAAGFLVK KELEYFAKAL 200
ESPARPFLAI LGGAKVSDKI PVIDNLLPKV NSLIIIGGMA LTFKKTLENV 250
KIGNSLFDEA GSKILGEIVE KAKKHNVEIV LPVDYVTADK FSADATVGSA 300
TTQRIPDGYM GSDVGPESVK LYQKTIAEAK TILWNGPPGV FELKPSPRPT 350
EATLDAAVKA AESGSIVIIG GGDTATVAAK YKAEDKISHV STGGGASLEL 400
LEGKELPGVA ALSSK 415
Length:415
Mass (Da):44,022
Last modified:July 1, 1989 - v1
Checksum:i508AC3F76CE35E81
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X13379 Genomic DNA. Translation: CAA31756.1.
S71096 Genomic DNA. Translation: AAB30809.1.
PIRiS02040. TVPLGC.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X13379 Genomic DNA. Translation: CAA31756.1 .
S71096 Genomic DNA. Translation: AAB30809.1 .
PIRi S02040. TVPLGC.

3D structure databases

ProteinModelPortali P09188.
SMRi P09188. Positions 2-414.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P09188.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence of the Penicillium chrysogenum phosphoglycerate kinase gene."
    van Solingen P., Muurling H., Koekman B., van den Berg J.
    Nucleic Acids Res. 16:11823-11823(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: GB 533.
  2. "Expression of the 3-phosphoglycerate kinase gene (pgkA) of Penicillium chrysogenum."
    Hoskins I.C., Roberts C.F.
    Mol. Gen. Genet. 243:270-276(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-22.
    Strain: ATCC 9480 / CBS 307.48 / NRRL 1951 / GB8 / QM 941.

Entry informationi

Entry nameiPGK_PENCH
AccessioniPrimary (citable) accession number: P09188
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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