ID   LUXA1_PHOLE             Reviewed;         354 AA.
AC   P09140;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   16-JUN-2009, entry version 55.
DE   RecName: Full=Alkanal monooxygenase alpha chain;
DE            EC=1.14.14.3;
DE   AltName: Full=Bacterial luciferase alpha chain;
GN   Name=luxA;
OS   Photobacterium leiognathi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Photobacterium.
OX   NCBI_TaxID=658;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=554;
RX   MEDLINE=89041570; PubMed=3186447; DOI=10.1093/nar/16.20.9855;
RA   Illiarinov B.A., Protopopova M.V., Karginov V.A., Mertvetsov N.P.,
RA   Gitelson J.I.;
RT   "Nucleotide sequence of part of Photobacterium leiognathi lux
RT   region.";
RL   Nucleic Acids Res. 16:9855-9855(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=554;
RX   MEDLINE=88251495; PubMed=3382442;
RA   Illarionov B.A., Protopopova M.V., Karginov V.A., Mertvetsov N.P.,
RA   Gitelson J.I.;
RT   "Nucleotide sequence of genes for alpha- and beta-subunits of
RT   luciferase from Photobacterium leiognathi.";
RL   Bioorg. Khim. 14:412-415(1988).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=554;
RX   MEDLINE=90185252; PubMed=2311938; DOI=10.1016/0378-1119(90)90117-A;
RA   Illarionov B.A., Blinov V.M., Donchenko A.P., Protopopova M.V.,
RA   Karginov V.A., Mertvetsov N.P., Gitelson J.I.;
RT   "Isolation of bioluminescent functions from Photobacterium leiognathi:
RT   analysis of luxA, luxB, luxG and neighboring genes.";
RL   Gene 86:89-94(1990).
CC   -!- FUNCTION: Light-emitting reaction in luminous bacteria.
CC   -!- CATALYTIC ACTIVITY: RCHO + reduced FMN + O(2) = RCOOH + FMN +
CC       H(2)O + light.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SIMILARITY: Belongs to the bacterial luciferase oxidoreductase
CC       family.
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DR   EMBL; X08036; CAA30831.1; -; Genomic_DNA.
DR   PIR; JQ0413; JQ0413.
DR   HSSP; P07740; 1BRL.
DR   BRENDA; 1.14.14.3; 349.
DR   GO; GO:0047646; F:alkanal monooxygenase (FMN-linked) activity; IEA:EC.
DR   GO; GO:0008218; P:bioluminescence; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR018235; Bacterial_luciferase_CS.
DR   InterPro; IPR011251; Luciferase-like.
DR   InterPro; IPR016048; Luciferase-like_sub.
DR   InterPro; IPR002103; Luciferase_bac.
DR   Gene3D; G3DSA:3.20.20.30; Luciferase_like; 1.
DR   Pfam; PF00296; Bac_luciferase; 1.
DR   PRINTS; PR00089; LUCIFERASE.
DR   PROSITE; PS00494; BACTERIAL_LUCIFERASE; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; Luminescence; Monooxygenase; Oxidoreductase;
KW   Photoprotein.
FT   CHAIN         1    354       Alkanal monooxygenase alpha chain.
FT                                /FTId=PRO_0000220164.
SQ   SEQUENCE   354 AA;  40371 MW;  569F6EEB903C7B90 CRC64;
     MKFGNICFSY QPPGESHKEV MDRFVRLGVA SEELNFDTFW TLEHHFTEFG LTGNLYVACA
     NILGRTKKLN VGTMGIVLPT AHPARQMEDL LLLDQMSKGR FNFGVVRGLY HKDFRVFGVT
     MEDSRSITED FHKMIMDGSK SGVLHTDGKN IEFPDVNVYP EAYLDKIPTC MTAESAATTT
     WLAERGLPMV LSWIITTSEK KAQMELYNEI AAEHGHDIHN IDHSMTFICS VNEDPEKAES
     VCRDFLSNWY ESYTNATNIF KDSNQTRGYD YHKGQWRDFV LQGHTDTRRR LDYSNNLNPV
     GTPEKCIEII QRDIDATGIN NITLGFEANG SEQEIIASME RFMTQVAPYL KDPK
//