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Protein

Protein HemX

Gene

hemX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Was suggested to be a uroporphyrinogen-III methyltransferase, but the function of the protein has not been experimentally determined.1 Publication

Enzyme and pathway databases

BioCyciEcoCyc:HEMX-MONOMER
MetaCyc:HEMX-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HemXCurated
Alternative name(s):
ORF XImported
Gene namesi
Name:hemX1 Publication
Ordered Locus Names:b3803, JW3775
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10433 hemX

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 57HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001352551 – 393Protein HemXAdd BLAST393

Proteomic databases

EPDiP09127
PaxDbiP09127
PRIDEiP09127

Interactioni

Subunit structurei

Homooligomer, possibly a homopentamer.1 Publication

Protein-protein interaction databases

BioGridi4259707, 160 interactors
DIPiDIP-9888N
IntActiP09127, 3 interactors
STRINGi316407.85676248

Structurei

3D structure databases

ProteinModelPortaliP09127
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105ECF Bacteria
COG2959 LUCA
HOGENOMiHOG000270899
InParanoidiP09127
KOiK02496
OMAiTRVRNLM
PhylomeDBiP09127

Family and domain databases

InterProiView protein in InterPro
IPR007470 HemX
PANTHERiPTHR38043 PTHR38043, 1 hit
PfamiView protein in Pfam
PF04375 HemX, 1 hit

Sequencei

Sequence statusi: Complete.

P09127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEQEKTSAV VEETREAVDT TSQPVATEKK SKNNTALILS AVAIAIALAA
60 70 80 90 100
GIGLYGWGKQ QAVNQTATSD ALANQLTALQ KAQESQKAEL EGIIKQQAAQ
110 120 130 140 150
LKQANRQQET LAKQLDEVQQ KVATISGSDA KTWLLAQADF LVKLAGRKLW
160 170 180 190 200
SDQDVTTAAA LLKSADASLA DMNDPSLITV RRAITDDIAS LSAVSQVDYD
210 220 230 240 250
GIILKLNQLS NQVDNLRLAD NDSDGSPMDS DGEELSSSIS EWRINLQKSW
260 270 280 290 300
QNFMDNFITI RRRDDTAVPL LAPNQDIYLR ENIRSRLLVA AQAVPRHQEE
310 320 330 340 350
TYRQALENVS TWVRAYYDTD DATTKAFLDE VDQLSQQNIS MDLPETLQSQ
360 370 380 390
AMLEKLMQTR VRNLLAQPAA GTTEAKPAPA PQADTPAAAP QGE
Length:393
Mass (Da):42,963
Last modified:July 1, 1989 - v1
Checksum:i9D272C6401D0E354
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13406 Genomic DNA Translation: CAA31772.1
X12614 Genomic DNA Translation: CAA31134.1
M87049 Genomic DNA Translation: AAA67599.1
U00096 Genomic DNA Translation: AAC76806.1
AP009048 Genomic DNA Translation: BAE77498.1
PIRiS02185
RefSeqiNP_418247.1, NC_000913.3
WP_000138997.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76806; AAC76806; b3803
BAE77498; BAE77498; BAE77498
GeneIDi948446
KEGGiecj:JW3775
eco:b3803
PATRICifig|1411691.4.peg.2905

Similar proteinsi

Entry informationi

Entry nameiHEMX_ECOLI
AccessioniPrimary (citable) accession number: P09127
Secondary accession number(s): Q2M8A8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: April 25, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health