Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Xylulose kinase

Gene

xylB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • xylulokinase activity Source: EcoCyc

GO - Biological processi

  • D-xylose catabolic process Source: EcoCyc
  • xylulose catabolic process Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Xylose metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:XYLULOKIN-MONOMER.
ECOL316407:JW3536-MONOMER.
MetaCyc:XYLULOKIN-MONOMER.
BRENDAi2.7.1.17. 2026.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylulose kinase (EC:2.7.1.17)
Short name:
Xylulokinase
Gene namesi
Name:xylB
Ordered Locus Names:b3564, JW3536
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11075. xylB.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000595491 – 484Xylulose kinaseAdd BLAST484

Proteomic databases

PaxDbiP09099.
PRIDEiP09099.

Interactioni

Protein-protein interaction databases

BioGridi4262539. 5 interactors.
IntActiP09099. 1 interactor.
STRINGi511145.b3564.

Structurei

Secondary structure

1484
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 7Combined sources6
Beta strandi9 – 17Combined sources9
Beta strandi23 – 30Combined sources8
Helixi45 – 62Combined sources18
Beta strandi70 – 75Combined sources6
Beta strandi80 – 83Combined sources4
Helixi102 – 111Combined sources10
Helixi115 – 119Combined sources5
Helixi128 – 138Combined sources11
Helixi140 – 143Combined sources4
Beta strandi148 – 150Combined sources3
Helixi152 – 161Combined sources10
Beta strandi165 – 167Combined sources3
Helixi168 – 172Combined sources5
Turni173 – 175Combined sources3
Turni179 – 182Combined sources4
Helixi186 – 190Combined sources5
Turni191 – 193Combined sources3
Helixi196 – 198Combined sources3
Beta strandi201 – 203Combined sources3
Beta strandi207 – 211Combined sources5
Helixi214 – 219Combined sources6
Beta strandi226 – 228Combined sources3
Helixi233 – 241Combined sources9
Beta strandi249 – 262Combined sources14
Beta strandi271 – 273Combined sources3
Beta strandi275 – 278Combined sources4
Beta strandi285 – 291Combined sources7
Helixi294 – 304Combined sources11
Helixi310 – 316Combined sources7
Helixi317 – 319Combined sources3
Beta strandi328 – 333Combined sources6
Beta strandi345 – 353Combined sources9
Helixi358 – 381Combined sources24
Turni382 – 384Combined sources3
Beta strandi390 – 394Combined sources5
Helixi395 – 397Combined sources3
Helixi400 – 410Combined sources11
Beta strandi414 – 418Combined sources5
Helixi424 – 436Combined sources13
Helixi442 – 445Combined sources4
Beta strandi451 – 455Combined sources5
Helixi459 – 479Combined sources21
Helixi480 – 483Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ITMX-ray2.10A/B1-484[»]
2NLXX-ray2.70A/B1-484[»]
ProteinModelPortaliP09099.
SMRiP09099.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP09099.

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.Curated

Phylogenomic databases

eggNOGiENOG4105CMG. Bacteria.
COG1070. LUCA.
HOGENOMiHOG000222138.
InParanoidiP09099.
KOiK00854.
OMAiEITGNLM.
PhylomeDBiP09099.

Family and domain databases

InterProiIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR006000. Xylulokinase.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000538. GlpK. 1 hit.
TIGRFAMsiTIGR01312. XylB. 1 hit.
PROSITEiPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P09099-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYIGIDLGTS GVKVILLNEQ GEVVAAQTEK LTVSRPHPLW SEQDPEQWWQ
60 70 80 90 100
ATDRAMKALG DQHSLQDVKA LGIAGQMHGA TLLDAQQRVL RPAILWNDGR
110 120 130 140 150
CAQECTLLEA RVPQSRVITG NLMMPGFTAP KLLWVQRHEP EIFRQIDKVL
160 170 180 190 200
LPKDYLRLRM TGEFASDMSD AAGTMWLDVA KRDWSDVMLQ ACDLSRDQMP
210 220 230 240 250
ALYEGSEITG ALLPEVAKAW GMATVPVVAG GGDNAAGAVG VGMVDANQAM
260 270 280 290 300
LSLGTSGVYF AVSEGFLSKP ESAVHSFCHA LPQRWHLMSV MLSAASCLDW
310 320 330 340 350
AAKLTGLSNV PALIAAAQQA DESAEPVWFL PYLSGERTPH NNPQAKGVFF
360 370 380 390 400
GLTHQHGPNE LARAVLEGVG YALADGMDVV HACGIKPQSV TLIGGGARSE
410 420 430 440 450
YWRQMLADIS GQQLDYRTGG DVGPALGAAR LAQIAANPEK SLIELLPQLP
460 470 480
LEQSHLPDAQ RYAAYQPRRE TFRRLYQQLL PLMA
Length:484
Mass (Da):52,618
Last modified:July 1, 1989 - v1
Checksum:i8CC62CBD546AFCA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K01996 Genomic DNA. Translation: AAA24769.1.
X04691 Genomic DNA. Translation: CAA28395.1.
U00039 Genomic DNA. Translation: AAB18541.1.
U00096 Genomic DNA. Translation: AAC76588.1.
AP009048 Genomic DNA. Translation: BAE77729.1.
PIRiA30266. KIECXY.
RefSeqiNP_418021.1. NC_000913.3.
WP_000275334.1. NZ_CP014272.1.

Genome annotation databases

EnsemblBacteriaiAAC76588; AAC76588; b3564.
BAE77729; BAE77729; BAE77729.
GeneIDi948133.
KEGGiecj:JW3536.
eco:b3564.
PATRICi32122604. VBIEscCol129921_3679.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K01996 Genomic DNA. Translation: AAA24769.1.
X04691 Genomic DNA. Translation: CAA28395.1.
U00039 Genomic DNA. Translation: AAB18541.1.
U00096 Genomic DNA. Translation: AAC76588.1.
AP009048 Genomic DNA. Translation: BAE77729.1.
PIRiA30266. KIECXY.
RefSeqiNP_418021.1. NC_000913.3.
WP_000275334.1. NZ_CP014272.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ITMX-ray2.10A/B1-484[»]
2NLXX-ray2.70A/B1-484[»]
ProteinModelPortaliP09099.
SMRiP09099.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262539. 5 interactors.
IntActiP09099. 1 interactor.
STRINGi511145.b3564.

Proteomic databases

PaxDbiP09099.
PRIDEiP09099.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76588; AAC76588; b3564.
BAE77729; BAE77729; BAE77729.
GeneIDi948133.
KEGGiecj:JW3536.
eco:b3564.
PATRICi32122604. VBIEscCol129921_3679.

Organism-specific databases

EchoBASEiEB1068.
EcoGeneiEG11075. xylB.

Phylogenomic databases

eggNOGiENOG4105CMG. Bacteria.
COG1070. LUCA.
HOGENOMiHOG000222138.
InParanoidiP09099.
KOiK00854.
OMAiEITGNLM.
PhylomeDBiP09099.

Enzyme and pathway databases

BioCyciEcoCyc:XYLULOKIN-MONOMER.
ECOL316407:JW3536-MONOMER.
MetaCyc:XYLULOKIN-MONOMER.
BRENDAi2.7.1.17. 2026.

Miscellaneous databases

EvolutionaryTraceiP09099.
PROiP09099.

Family and domain databases

InterProiIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR006000. Xylulokinase.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000538. GlpK. 1 hit.
TIGRFAMsiTIGR01312. XylB. 1 hit.
PROSITEiPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiXYLB_ECOLI
AccessioniPrimary (citable) accession number: P09099
Secondary accession number(s): Q2M7M7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: November 2, 2016
This is version 125 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.