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Protein

Putative non-structural protein 3b

Gene

3b

Organism
Porcine transmissible gastroenteritis coronavirus (strain Purdue) (TGEV)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Could be the product of a pseudogene.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Putative non-structural protein 3b
Short name:
ns3b
Alternative name(s):
Accessory protein 3b
Non-structural protein 3-1
X2b protein
Gene namesi
ORF Names:3b
OrganismiPorcine transmissible gastroenteritis coronavirus (strain Purdue) (TGEV)
Taxonomic identifieri11151 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageNidoviralesCoronaviridaeCoronavirinaeAlphacoronavirus
Virus hostiSus scrofa (Pig) [TaxID: 9823]
Proteomesi
  • UP000001440 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei47 – 67HelicalSequence analysisAdd BLAST21
Transmembranei75 – 95HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001060751 – 244Putative non-structural protein 3bAdd BLAST244

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi234 – 237Poly-Glu4

Sequence similaritiesi

Belongs to the coronaviruses NS3b protein family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090001QF

Family and domain databases

InterProiView protein in InterPro
IPR004293 Coronavirus_Orf3b
PfamiView protein in Pfam
PF03053 Corona_NS3b, 1 hit

Sequencei

Sequence statusi: Complete.

P09047-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGGLFLSTL SFVIVSNHSI VNNTANVHHI QQERVIVQQH QVVSARTQNY
60 70 80 90 100
YPEFSIAVLF VSFLALYRST NFKTCVGILM FKILSMTLLG PMLIAYGYYI
110 120 130 140 150
DGIVTTTVLS LRFVYLAYFW YVNSRFEFIL YNTTTLMFVH GRAAPFMRSS
160 170 180 190 200
HSSIYVTLYG GINYMFVNDL TLHFVDPMLV SIAIRGLAHA DLTVVRAVEL
210 220 230 240
LNGDFIYVFS QEPVVGVYNA AFSQAVLNEI DLKEEEEDHT YDVS
Length:244
Mass (Da):27,724
Last modified:April 17, 2007 - v2
Checksum:i61E53A5D3F8BFED8
GO

Sequence cautioni

The sequence CAA29671 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti8S → N (PubMed:2549745).Curated1
Sequence conflicti31Q → K (PubMed:2549745).Curated1
Sequence conflicti41Q → H (PubMed:10805807).Curated1
Sequence conflicti59L → P in CAA31287 (PubMed:2548340).Curated1
Sequence conflicti114V → A (PubMed:2549745).Curated1
Sequence conflicti147M → K (PubMed:2549745).Curated1
Sequence conflicti239H → R (PubMed:2549745).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X06371 Genomic RNA Translation: CAA29671.1 Different initiation.
X12800 Genomic DNA Translation: CAA31287.1
AJ271965 Genomic RNA No translation available.
PIRiS01740
S04890

Similar proteinsi

Entry informationi

Entry nameiNS3B_CVPPU
AccessioniPrimary (citable) accession number: P09047
Secondary accession number(s): Q85086
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: April 17, 2007
Last modified: February 15, 2017
This is version 55 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome