Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Homeobox protein Hox-B5

Gene

hoxb5

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi155 – 214HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-B5
Alternative name(s):
Xhox-1B
XlHbox-4
Gene namesi
Name:hoxb5
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000200134‹1 – 230Homeobox protein Hox-B5Add BLAST›230

Proteomic databases

PRIDEiP09019

Expressioni

Developmental stagei

Embryo.

Structurei

3D structure databases

ProteinModelPortaliP09019
SMRiP09019
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi137 – 142Antp-type hexapeptide6

Sequence similaritiesi

Belongs to the Antp homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

HOVERGENiHBG016849

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017995 Homeobox_antennapedia
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00025 ANTENNAPEDIA
PR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Fragment.

P09019-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GGGGGNVSGS YREAGGNMQP GAYGSYNYTG MDLSISRTAA PTYGGDNSFP
60 70 80 90 100
GQESSRFRAN QNCPLSTPDP LPCAKSQKSE LSPADPATSS AHFTETEETS
110 120 130 140 150
ASSETDESTP RSGAPPRALQ DNCSPGAAGT DGQSPQIFPW MRKLHINHDM
160 170 180 190 200
AGPDGKRART AYTRYQTLEL EKEFHFNRYL TRRRRIEIAH TLCLSERQIK
210 220 230
IWFQNRRMKW KKDNKLKSMS LATGSSAFQP
Length:230
Mass (Da):25,276
Last modified:November 1, 1988 - v1
Checksum:iAD040C030F85532B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07104 mRNA Translation: CAA30125.1
M26883 Genomic DNA Translation: AAA49755.1
PIRiS00592
UniGeneiXl.19994

Similar proteinsi

Entry informationi

Entry nameiHXB5_XENLA
AccessioniPrimary (citable) accession number: P09019
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1988
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health