SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P09007

- SRD1_YEAST

UniProt

P09007 - SRD1_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Pre-rRNA-processing protein SRD1

Gene
SRD1, YCR018C, YCR18C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Plays a direct or indirect role in pre-rRNA processing.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri168 – 19326GATA-typeAdd
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. rRNA processing Source: SGD
Complete GO annotation...

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-29333-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pre-rRNA-processing protein SRD1
Alternative name(s):
Suppressor of rRNA-processing defect protein 1
Gene namesi
Name:SRD1
Ordered Locus Names:YCR018C
ORF Names:YCR18C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome III

Organism-specific databases

CYGDiYCR018c.
SGDiS000000611. SRD1.

Subcellular locationi

Cytoplasm. Nucleus 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 221221Pre-rRNA-processing protein SRD1PRO_0000083482Add
BLAST

Proteomic databases

PaxDbiP09007.

Expressioni

Gene expression databases

GenevestigatoriP09007.

Interactioni

Protein-protein interaction databases

BioGridi30997. 9 interactions.
MINTiMINT-4478353.

Structurei

3D structure databases

ProteinModelPortaliP09007.
SMRiP09007. Positions 167-203.

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri168 – 19326GATA-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG311416.
GeneTreeiENSGT00530000068273.
KOiK14858.
OMAiCNSERRT.
OrthoDBiEOG7ZPNX9.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiIPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00320. GATA. 1 hit.
[Graphical view]
SMARTiSM00401. ZnF_GATA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P09007-1 [UniParc]FASTAAdd to Basket

« Hide

MRYNNYDNSG SSFLTRVVKK SDMEKTLLLN REIDDWKSND KKKAYKERGR    50
VYASCSFIEV SFSQIRAVDV EKKIENAEQL RDLTRNIVKN KTSSLNEITP 100
SKNRVTSACN SERRTTSQEA NNLEGYHSCA QGTSRSASIT KKYSKKTTSR 150
PKREKRQTIL PNGEIKECSK CKDTWTIQWR SGPDQNRELC SPCGLAYGKR 200
LKKENEKKRQ AADKRIDRNN P 221
Length:221
Mass (Da):25,514
Last modified:March 15, 2004 - v2
Checksum:iD9519E6564546687
GO

Sequence cautioni

The sequence CAA29638.1 differs from that shown. Reason: Frameshift at position 218.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti106 – 1061T → I in CAA29638. 1 Publication
Sequence conflicti192 – 1921P → R in CAA30298. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X06322 Genomic DNA. Translation: CAA29638.1. Frameshift.
X07388 Genomic DNA. Translation: CAA30298.1. Sequence problems.
X59720 Genomic DNA. Translation: CAA42309.2.
BK006937 Genomic DNA. Translation: DAA07495.1.
PIRiS07396.
S19428.
RefSeqiNP_009944.2. NM_001178731.1.

Genome annotation databases

EnsemblFungiiYCR018C; YCR018C; YCR018C.
GeneIDi850377.
KEGGisce:YCR018C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X06322 Genomic DNA. Translation: CAA29638.1 . Frameshift.
X07388 Genomic DNA. Translation: CAA30298.1 . Sequence problems.
X59720 Genomic DNA. Translation: CAA42309.2 .
BK006937 Genomic DNA. Translation: DAA07495.1 .
PIRi S07396.
S19428.
RefSeqi NP_009944.2. NM_001178731.1.

3D structure databases

ProteinModelPortali P09007.
SMRi P09007. Positions 167-203.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 30997. 9 interactions.
MINTi MINT-4478353.

Proteomic databases

PaxDbi P09007.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YCR018C ; YCR018C ; YCR018C .
GeneIDi 850377.
KEGGi sce:YCR018C.

Organism-specific databases

CYGDi YCR018c.
SGDi S000000611. SRD1.

Phylogenomic databases

eggNOGi NOG311416.
GeneTreei ENSGT00530000068273.
KOi K14858.
OMAi CNSERRT.
OrthoDBi EOG7ZPNX9.

Enzyme and pathway databases

BioCyci YEAST:G3O-29333-MONOMER.

Miscellaneous databases

NextBioi 965878.

Gene expression databases

Genevestigatori P09007.

Family and domain databases

Gene3Di 3.30.50.10. 1 hit.
InterProi IPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view ]
Pfami PF00320. GATA. 1 hit.
[Graphical view ]
SMARTi SM00401. ZnF_GATA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Polymorphisms on the right arm of yeast chromosome III associated with Ty transposition and recombination events."
    Warmington J.R., Green R.P., Newlon C.S., Oliver S.G.
    Nucleic Acids Res. 15:8963-8982(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: CN31C and S288c / GRF88.
  2. "The complete DNA sequence of yeast chromosome III."
    Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
    , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
    Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Valles G., Volckaerts G.
    Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION TO 106 AND C-TERMINUS.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. "SRD1, a Saccharomyces cerevisiae suppressor of the temperature-sensitive pre-rRNA processing defect of rrp1-1."
    Fabian G.R., Hess S.M., Hopper A.K.
    Genetics 124:497-504(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  6. "SRD1, a S. cerevisiae gene affecting pre-rRNA processing contains a C2/C2 zinc finger motif."
    Hess S.M., Stanford D.R., Hopper A.K.
    Nucleic Acids Res. 22:1265-1271(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.
  7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  8. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSRD1_YEAST
AccessioniPrimary (citable) accession number: P09007
Secondary accession number(s): D6VR26, P09008, Q06989
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: March 15, 2004
Last modified: June 11, 2014
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2100 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

External Data

Dasty 3

Similar proteinsi