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Protein

Pre-rRNA-processing protein SRD1

Gene

SRD1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a direct or indirect role in pre-rRNA processing.1 Publication

Miscellaneous

Present with 2100 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri168 – 193GATA-typeAdd BLAST26

GO - Molecular functioni

GO - Biological processi

  • cell differentiation Source: GO_Central
  • rRNA processing Source: SGD

Keywordsi

Molecular functionDNA-binding
Biological processrRNA processing
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-29333-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Pre-rRNA-processing protein SRD1
Alternative name(s):
Suppressor of rRNA-processing defect protein 1
Gene namesi
Name:SRD1
Ordered Locus Names:YCR018C
ORF Names:YCR18C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCR018C
SGDiS000000611 SRD1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000834821 – 221Pre-rRNA-processing protein SRD1Add BLAST221

Proteomic databases

PaxDbiP09007
PRIDEiP09007

PTM databases

iPTMnetiP09007

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi30997, 10 interactors
STRINGi4932.YCR018C

Structurei

3D structure databases

ProteinModelPortaliP09007
SMRiP09007
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri168 – 193GATA-typeAdd BLAST26

Keywords - Domaini

Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00530000068273
InParanoidiP09007
KOiK14858
OrthoDBiEOG092C4UKR

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00320 GATA, 1 hit
SMARTiView protein in SMART
SM00401 ZnF_GATA, 1 hit

Sequencei

Sequence statusi: Complete.

P09007-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYNNYDNSG SSFLTRVVKK SDMEKTLLLN REIDDWKSND KKKAYKERGR
60 70 80 90 100
VYASCSFIEV SFSQIRAVDV EKKIENAEQL RDLTRNIVKN KTSSLNEITP
110 120 130 140 150
SKNRVTSACN SERRTTSQEA NNLEGYHSCA QGTSRSASIT KKYSKKTTSR
160 170 180 190 200
PKREKRQTIL PNGEIKECSK CKDTWTIQWR SGPDQNRELC SPCGLAYGKR
210 220
LKKENEKKRQ AADKRIDRNN P
Length:221
Mass (Da):25,514
Last modified:March 15, 2004 - v2
Checksum:iD9519E6564546687
GO

Sequence cautioni

The sequence CAA29638 differs from that shown. Reason: Frameshift at position 218.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti106T → I in CAA29638 (PubMed:2825123).Curated1
Sequence conflicti192P → R in CAA30298 (PubMed:2825123).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X06322 Genomic DNA Translation: CAA29638.1 Frameshift.
X07388 Genomic DNA Translation: CAA30298.1 Sequence problems.
X59720 Genomic DNA Translation: CAA42309.2
BK006937 Genomic DNA Translation: DAA07495.1
PIRiS07396
S19428
RefSeqiNP_009944.2, NM_001178731.1

Genome annotation databases

EnsemblFungiiCAA42309; CAA42309; CAA42309
YCR018C; YCR018C; YCR018C
GeneIDi850377
KEGGisce:YCR018C

Similar proteinsi

Entry informationi

Entry nameiSRD1_YEAST
AccessioniPrimary (citable) accession number: P09007
Secondary accession number(s): D6VR26, P09008, Q06989
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: March 15, 2004
Last modified: June 20, 2018
This is version 135 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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