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P09007 (SRD1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pre-rRNA-processing protein SRD1
Alternative name(s):
Suppressor of rRNA-processing defect protein 1
Gene names
Name:SRD1
Ordered Locus Names:YCR018C
ORF Names:YCR18C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plays a direct or indirect role in pre-rRNA processing. Ref.5

Subcellular location

Cytoplasm. Nucleus Ref.7.

Miscellaneous

Present with 2100 molecules/cell in log phase SD medium.

Sequence similarities

Contains 1 GATA-type zinc finger.

Sequence caution

The sequence CAA29638.1 differs from that shown. Reason: Frameshift at position 218.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221Pre-rRNA-processing protein SRD1
PRO_0000083482

Regions

Zinc finger168 – 19326GATA-type

Experimental info

Sequence conflict1061T → I in CAA29638. Ref.1
Sequence conflict1921P → R in CAA30298. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P09007 [UniParc].

Last modified March 15, 2004. Version 2.
Checksum: D9519E6564546687

FASTA22125,514
        10         20         30         40         50         60 
MRYNNYDNSG SSFLTRVVKK SDMEKTLLLN REIDDWKSND KKKAYKERGR VYASCSFIEV 

        70         80         90        100        110        120 
SFSQIRAVDV EKKIENAEQL RDLTRNIVKN KTSSLNEITP SKNRVTSACN SERRTTSQEA 

       130        140        150        160        170        180 
NNLEGYHSCA QGTSRSASIT KKYSKKTTSR PKREKRQTIL PNGEIKECSK CKDTWTIQWR 

       190        200        210        220 
SGPDQNRELC SPCGLAYGKR LKKENEKKRQ AADKRIDRNN P 

« Hide

References

« Hide 'large scale' references
[1]"Polymorphisms on the right arm of yeast chromosome III associated with Ty transposition and recombination events."
Warmington J.R., Green R.P., Newlon C.S., Oliver S.G.
Nucleic Acids Res. 15:8963-8982(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: CN31C and S288c / GRF88.
[2]"The complete DNA sequence of yeast chromosome III."
Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M. expand/collapse author list , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Valles G., Volckaerts G.
Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
Cited for: SEQUENCE REVISION TO 106 AND C-TERMINUS.
[4]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"SRD1, a Saccharomyces cerevisiae suppressor of the temperature-sensitive pre-rRNA processing defect of rrp1-1."
Fabian G.R., Hess S.M., Hopper A.K.
Genetics 124:497-504(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[6]"SRD1, a S. cerevisiae gene affecting pre-rRNA processing contains a C2/C2 zinc finger motif."
Hess S.M., Stanford D.R., Hopper A.K.
Nucleic Acids Res. 22:1265-1271(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
[7]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[8]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X06322 Genomic DNA. Translation: CAA29638.1. Frameshift.
X07388 Genomic DNA. Translation: CAA30298.1. Sequence problems.
X59720 Genomic DNA. Translation: CAA42309.2.
BK006937 Genomic DNA. Translation: DAA07495.1.
PIRS07396.
S19428.
RefSeqNP_009944.2. NM_001178731.1.

3D structure databases

ProteinModelPortalP09007.
SMRP09007. Positions 164-201.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid30997. 9 interactions.
MINTMINT-4478353.

Proteomic databases

PaxDbP09007.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYCR018C; YCR018C; YCR018C.
GeneID850377.
KEGGsce:YCR018C.

Organism-specific databases

CYGDYCR018c.
SGDS000000611. SRD1.

Phylogenomic databases

eggNOGNOG311416.
GeneTreeENSGT00530000068273.
KOK14858.
OMACNSERRT.
OrthoDBEOG7ZPNX9.

Enzyme and pathway databases

BioCycYEAST:G3O-29333-MONOMER.

Gene expression databases

GenevestigatorP09007.

Family and domain databases

Gene3D3.30.50.10. 1 hit.
InterProIPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamPF00320. GATA. 1 hit.
[Graphical view]
SMARTSM00401. ZnF_GATA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio965878.

Entry information

Entry nameSRD1_YEAST
AccessionPrimary (citable) accession number: P09007
Secondary accession number(s): D6VR26, P09008, Q06989
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: March 15, 2004
Last modified: March 19, 2014
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome III

Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families