Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P09007

- SRD1_YEAST

UniProt

P09007 - SRD1_YEAST

Protein

Pre-rRNA-processing protein SRD1

Gene

SRD1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 109 (01 Oct 2014)
      Sequence version 2 (15 Mar 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Plays a direct or indirect role in pre-rRNA processing.1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri168 – 19326GATA-typeAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. rRNA processing Source: SGD

    Keywords - Biological processi

    rRNA processing

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciYEAST:G3O-29333-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pre-rRNA-processing protein SRD1
    Alternative name(s):
    Suppressor of rRNA-processing defect protein 1
    Gene namesi
    Name:SRD1
    Ordered Locus Names:YCR018C
    ORF Names:YCR18C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome III

    Organism-specific databases

    CYGDiYCR018c.
    SGDiS000000611. SRD1.

    Subcellular locationi

    Cytoplasm 1 Publication. Nucleus 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221Pre-rRNA-processing protein SRD1PRO_0000083482Add
    BLAST

    Proteomic databases

    PaxDbiP09007.

    Expressioni

    Gene expression databases

    GenevestigatoriP09007.

    Interactioni

    Protein-protein interaction databases

    BioGridi30997. 9 interactions.
    MINTiMINT-4478353.

    Structurei

    3D structure databases

    ProteinModelPortaliP09007.
    SMRiP09007. Positions 167-203.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 GATA-type zinc finger.Curated

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri168 – 19326GATA-typeAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG311416.
    GeneTreeiENSGT00530000068273.
    KOiK14858.
    OMAiCNSERRT.
    OrthoDBiEOG7ZPNX9.

    Family and domain databases

    Gene3Di3.30.50.10. 1 hit.
    InterProiIPR000679. Znf_GATA.
    IPR013088. Znf_NHR/GATA.
    [Graphical view]
    PfamiPF00320. GATA. 1 hit.
    [Graphical view]
    SMARTiSM00401. ZnF_GATA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P09007-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRYNNYDNSG SSFLTRVVKK SDMEKTLLLN REIDDWKSND KKKAYKERGR    50
    VYASCSFIEV SFSQIRAVDV EKKIENAEQL RDLTRNIVKN KTSSLNEITP 100
    SKNRVTSACN SERRTTSQEA NNLEGYHSCA QGTSRSASIT KKYSKKTTSR 150
    PKREKRQTIL PNGEIKECSK CKDTWTIQWR SGPDQNRELC SPCGLAYGKR 200
    LKKENEKKRQ AADKRIDRNN P 221
    Length:221
    Mass (Da):25,514
    Last modified:March 15, 2004 - v2
    Checksum:iD9519E6564546687
    GO

    Sequence cautioni

    The sequence CAA29638.1 differs from that shown. Reason: Frameshift at position 218.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti106 – 1061T → I in CAA29638. (PubMed:2825123)Curated
    Sequence conflicti192 – 1921P → R in CAA30298. (PubMed:2825123)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X06322 Genomic DNA. Translation: CAA29638.1. Frameshift.
    X07388 Genomic DNA. Translation: CAA30298.1. Sequence problems.
    X59720 Genomic DNA. Translation: CAA42309.2.
    BK006937 Genomic DNA. Translation: DAA07495.1.
    PIRiS07396.
    S19428.
    RefSeqiNP_009944.2. NM_001178731.1.

    Genome annotation databases

    EnsemblFungiiYCR018C; YCR018C; YCR018C.
    GeneIDi850377.
    KEGGisce:YCR018C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X06322 Genomic DNA. Translation: CAA29638.1 . Frameshift.
    X07388 Genomic DNA. Translation: CAA30298.1 . Sequence problems.
    X59720 Genomic DNA. Translation: CAA42309.2 .
    BK006937 Genomic DNA. Translation: DAA07495.1 .
    PIRi S07396.
    S19428.
    RefSeqi NP_009944.2. NM_001178731.1.

    3D structure databases

    ProteinModelPortali P09007.
    SMRi P09007. Positions 167-203.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 30997. 9 interactions.
    MINTi MINT-4478353.

    Proteomic databases

    PaxDbi P09007.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YCR018C ; YCR018C ; YCR018C .
    GeneIDi 850377.
    KEGGi sce:YCR018C.

    Organism-specific databases

    CYGDi YCR018c.
    SGDi S000000611. SRD1.

    Phylogenomic databases

    eggNOGi NOG311416.
    GeneTreei ENSGT00530000068273.
    KOi K14858.
    OMAi CNSERRT.
    OrthoDBi EOG7ZPNX9.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-29333-MONOMER.

    Miscellaneous databases

    NextBioi 965878.

    Gene expression databases

    Genevestigatori P09007.

    Family and domain databases

    Gene3Di 3.30.50.10. 1 hit.
    InterProi IPR000679. Znf_GATA.
    IPR013088. Znf_NHR/GATA.
    [Graphical view ]
    Pfami PF00320. GATA. 1 hit.
    [Graphical view ]
    SMARTi SM00401. ZnF_GATA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Polymorphisms on the right arm of yeast chromosome III associated with Ty transposition and recombination events."
      Warmington J.R., Green R.P., Newlon C.S., Oliver S.G.
      Nucleic Acids Res. 15:8963-8982(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: CN31C and S288c / GRF88.
    2. "The complete DNA sequence of yeast chromosome III."
      Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
      , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
      Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Valles G., Volckaerts G.
      Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION TO 106 AND C-TERMINUS.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. "SRD1, a Saccharomyces cerevisiae suppressor of the temperature-sensitive pre-rRNA processing defect of rrp1-1."
      Fabian G.R., Hess S.M., Hopper A.K.
      Genetics 124:497-504(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    6. "SRD1, a S. cerevisiae gene affecting pre-rRNA processing contains a C2/C2 zinc finger motif."
      Hess S.M., Stanford D.R., Hopper A.K.
      Nucleic Acids Res. 22:1265-1271(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: CHARACTERIZATION.
    7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    8. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSRD1_YEAST
    AccessioniPrimary (citable) accession number: P09007
    Secondary accession number(s): D6VR26, P09008, Q06989
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1988
    Last sequence update: March 15, 2004
    Last modified: October 1, 2014
    This is version 109 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2100 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome III
      Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

    External Data

    Dasty 3