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Protein

Odorant-binding protein

Gene

Obp1f

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

This protein is found in nasal epithelium and it binds a wide variety of chemical odorants.

GO - Molecular functioni

  • odorant binding Source: RGD
  • transporter activity Source: InterPro

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Olfaction, Sensory transduction, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Odorant-binding protein
Short name:
OBP
Gene namesi
Name:Obp1f
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi621639. Obp1f.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 151 PublicationAdd BLAST15
ChainiPRO_000001793616 – 172Odorant-binding proteinAdd BLAST157

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi60 ↔ 641 Publication
Disulfide bondi79 ↔ 1701 Publication

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP08937.
PRIDEiP08937.

Expressioni

Gene expression databases

BgeeiENSRNOG00000049515.
GenevisibleiP08937. RN.

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064887.

Structurei

Secondary structure

1172
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi25 – 28Combined sources4
Beta strandi33 – 41Combined sources9
Helixi42 – 44Combined sources3
Beta strandi54 – 60Combined sources7
Helixi62 – 64Combined sources3
Beta strandi66 – 75Combined sources10
Beta strandi78 – 88Combined sources11
Beta strandi94 – 109Combined sources16
Beta strandi111 – 121Combined sources11
Beta strandi127 – 137Combined sources11
Helixi141 – 153Combined sources13
Helixi158 – 160Combined sources3
Helixi165 – 167Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3FIQX-ray1.60A/B17-172[»]
ProteinModelPortaliP08937.
SMRiP08937.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP08937.

Family & Domainsi

Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JFBS. Eukaryota.
ENOG41116JK. LUCA.
GeneTreeiENSGT00730000111347.
HOGENOMiHOG000231354.
HOVERGENiHBG098951.
InParanoidiP08937.
OMAiWHSILMA.
OrthoDBiEOG091G0RS1.
TreeFamiTF338197.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR022272. Lipocalin_CS.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
IPR002448. Odour-bd.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR01173. ODORANTBNDNG.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00213. LIPOCALIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P08937-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKFLLIVLA LGVSCAHHEN LDISPSEVNG DWRTLYIVAD NVEKVAEGGS
60 70 80 90 100
LRAYFQHMEC GDECQELKII FNVKLDSECQ THTVVGQKHE DGRYTTDYSG
110 120 130 140 150
RNYFHVLKKT DDIIFFHNVN VDESGRRQCD LVAGKREDLN KAQKQELRKL
160 170
AEEYNIPNEN TQHLVPTDTC NQ
Length:172
Mass (Da):19,699
Last modified:November 1, 1988 - v1
Checksum:i9DAFFDEF67F724DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03093 mRNA. Translation: AAA41736.1.
PIRiA28713.
RefSeqiNP_620258.1. NM_138903.1.
UniGeneiRn.9718.

Genome annotation databases

EnsembliENSRNOT00000073734; ENSRNOP00000064887; ENSRNOG00000049515.
GeneIDi192267.
KEGGirno:192267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03093 mRNA. Translation: AAA41736.1.
PIRiA28713.
RefSeqiNP_620258.1. NM_138903.1.
UniGeneiRn.9718.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3FIQX-ray1.60A/B17-172[»]
ProteinModelPortaliP08937.
SMRiP08937.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064887.

Proteomic databases

PaxDbiP08937.
PRIDEiP08937.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000073734; ENSRNOP00000064887; ENSRNOG00000049515.
GeneIDi192267.
KEGGirno:192267.

Organism-specific databases

CTDi192267.
RGDi621639. Obp1f.

Phylogenomic databases

eggNOGiENOG410JFBS. Eukaryota.
ENOG41116JK. LUCA.
GeneTreeiENSGT00730000111347.
HOGENOMiHOG000231354.
HOVERGENiHBG098951.
InParanoidiP08937.
OMAiWHSILMA.
OrthoDBiEOG091G0RS1.
TreeFamiTF338197.

Miscellaneous databases

EvolutionaryTraceiP08937.
PROiP08937.

Gene expression databases

BgeeiENSRNOG00000049515.
GenevisibleiP08937. RN.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR022272. Lipocalin_CS.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
IPR002448. Odour-bd.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR01173. ODORANTBNDNG.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00213. LIPOCALIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOBP_RAT
AccessioniPrimary (citable) accession number: P08937
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1988
Last modified: November 2, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.