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P08754

- GNAI3_HUMAN

UniProt

P08754 - GNAI3_HUMAN

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Protein

Guanine nucleotide-binding protein G(k) subunit alpha

Gene
GNAI3
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi47 – 471Magnesium By similarity
Metal bindingi181 – 1811Magnesium By similarity
Binding sitei326 – 3261GTP; via amide nitrogen By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi40 – 478GTP By similarity
Nucleotide bindingi175 – 1817GTP By similarity
Nucleotide bindingi200 – 2045GTP By similarity
Nucleotide bindingi269 – 2724GTP By similarity

GO - Molecular functioni

  1. G-protein beta/gamma-subunit complex binding Source: RefGenome
  2. G-protein coupled serotonin receptor binding Source: RefGenome
  3. GTPase activity Source: InterPro
  4. GTP binding Source: UniProtKB-KW
  5. metal ion binding Source: UniProtKB-KW
  6. signal transducer activity Source: UniProtKB-KW

GO - Biological processi

  1. adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Source: Reactome
  2. adenylate cyclase-modulating G-protein coupled receptor signaling pathway Source: InterPro
  3. blood coagulation Source: Reactome
  4. cell cycle Source: UniProtKB-KW
  5. cell division Source: UniProtKB
  6. negative regulation of adenylate cyclase activity Source: ProtInc
  7. platelet activation Source: Reactome
  8. synaptic transmission Source: Reactome
  9. transport Source: ProtInc
  10. vesicle fusion Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Transducer

Keywords - Biological processi

Cell cycle, Cell division

Keywords - Ligandi

GTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_15333. Adenylate cyclase inhibitory pathway.
REACT_15426. PLC beta mediated events.
REACT_15457. G-protein activation.
REACT_19231. G alpha (i) signalling events.
REACT_19327. G alpha (s) signalling events.
REACT_19333. G alpha (z) signalling events.
REACT_20653. ADP signalling through P2Y purinoceptor 12.
SignaLinkiP08754.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanine nucleotide-binding protein G(k) subunit alpha
Alternative name(s):
G(i) alpha-3
Gene namesi
Name:GNAI3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:4387. GNAI3.

Subcellular locationi

Cytoplasm. Cell membrane. Cytoplasmcytoskeletonmicrotubule organizing centercentrosome
Note: Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody.1 Publication

GO - Cellular componenti

  1. centrosome Source: UniProtKB
  2. cytoplasm Source: UniProtKB
  3. extracellular vesicular exosome Source: UniProt
  4. extrinsic component of cytoplasmic side of plasma membrane Source: RefGenome
  5. Golgi apparatus Source: Ensembl
  6. heterotrimeric G-protein complex Source: RefGenome
  7. lysosomal membrane Source: UniProtKB
  8. membrane raft Source: Ensembl
  9. midbody Source: UniProtKB
  10. plasma membrane Source: Ensembl
  11. zymogen granule Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Cytoskeleton, Membrane

Pathology & Biotechi

Involvement in diseasei

Auriculocondylar syndrome 1 (ARCND1) [MIM:602483]: An autosomal dominant craniofacial malformation syndrome characterized by variable mandibular anomalies, including mild to severe micrognathia, temporomandibular joint ankylosis, cleft palate, and a characteristic ear malformation that consists of separation of the lobule from the external ear, giving the appearance of a question mark (question-mark ear). Other frequently described features include prominent cheeks, cupped and posteriorly rotated ears, preauricular tags, and microstomia.
Note: The disease is caused by mutations affecting the gene represented in this entry.1 Publication
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti40 – 401G → R in ARCND1. 1 Publication
VAR_068558

Keywords - Diseasei

Disease mutation

Organism-specific databases

MIMi602483. phenotype.
Orphaneti137888. Auriculocondylar syndrome.
PharmGKBiPA173.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 354353Guanine nucleotide-binding protein G(k) subunit alphaPRO_0000203692Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycine By similarity
Lipidationi3 – 31S-palmitoyl cysteine By similarity
Modified residuei178 – 1781ADP-ribosylarginine; by cholera toxin By similarity
Modified residuei351 – 3511ADP-ribosylcysteine; by pertussis toxin By similarity

Keywords - PTMi

ADP-ribosylation, Lipoprotein, Myristate, Palmitate

Proteomic databases

MaxQBiP08754.
PaxDbiP08754.
PeptideAtlasiP08754.
PRIDEiP08754.

PTM databases

PhosphoSiteiP08754.

Expressioni

Gene expression databases

ArrayExpressiP08754.
BgeeiP08754.
CleanExiHS_GNAI3.
GenevestigatoriP08754.

Organism-specific databases

HPAiCAB022099.

Interactioni

Subunit structurei

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1. Interacts (via active GTP- or inactive GDP-bound form) with RGS14 By similarity.

Protein-protein interaction databases

BioGridi109035. 59 interactions.
IntActiP08754. 21 interactions.
MINTiMINT-1146232.
STRINGi9606.ENSP00000358867.

Structurei

Secondary structure

1
354
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi34 – 396
Helixi46 – 5712
Helixi63 – 686
Helixi70 – 9122
Helixi100 – 11011
Turni111 – 1166
Helixi121 – 13111
Helixi134 – 1418
Helixi142 – 1454
Helixi152 – 1576
Helixi159 – 1624
Helixi171 – 1755
Beta strandi183 – 1919
Beta strandi194 – 2018
Helixi205 – 21410
Beta strandi219 – 2268
Helixi227 – 2315
Beta strandi237 – 2415
Helixi242 – 25413
Helixi257 – 2593
Beta strandi262 – 2698
Helixi271 – 2788
Helixi283 – 2853
Helixi296 – 30813
Turni314 – 3163
Beta strandi319 – 3235
Helixi329 – 34618

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IHBX-ray2.71A32-354[»]
2ODEX-ray1.90A/C4-350[»]
2V4ZX-ray2.80A4-350[»]
4G5OX-ray2.90A/B/C/D25-354[»]
4G5RX-ray3.48A/B/C/D25-354[»]
4G5SX-ray3.62A/B/C/D25-354[»]
ProteinModelPortaliP08754.
SMRiP08754. Positions 5-348.

Miscellaneous databases

EvolutionaryTraceiP08754.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG322962.
HOGENOMiHOG000038730.
HOVERGENiHBG063184.
InParanoidiP08754.
KOiK04630.
OMAiGEAARAX.
OrthoDBiEOG72C50B.
PhylomeDBiP08754.
TreeFamiTF300673.

Family and domain databases

Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001408. Gprotein_alpha_I.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00318. GPROTEINA.
PR00441. GPROTEINAI.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P08754-1 [UniParc]FASTAAdd to Basket

« Hide

MGCTLSAEDK AAVERSKMID RNLREDGEKA AKEVKLLLLG AGESGKSTIV    50
KQMKIIHEDG YSEDECKQYK VVVYSNTIQS IIAIIRAMGR LKIDFGEAAR 100
ADDARQLFVL AGSAEEGVMT PELAGVIKRL WRDGGVQACF SRSREYQLND 150
SASYYLNDLD RISQSNYIPT QQDVLRTRVK TTGIVETHFT FKDLYFKMFD 200
VGGQRSERKK WIHCFEGVTA IIFCVALSDY DLVLAEDEEM NRMHESMKLF 250
DSICNNKWFT ETSIILFLNK KDLFEEKIKR SPLTICYPEY TGSNTYEEAA 300
AYIQCQFEDL NRRKDTKEIY THFTCATDTK NVQFVFDAVT DVIIKNNLKE 350
CGLY 354
Length:354
Mass (Da):40,532
Last modified:January 23, 2007 - v3
Checksum:iEAB6B4DD3646BC01
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti40 – 401G → R in ARCND1. 1 Publication
VAR_068558

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti21 – 211R → C no nucleotide entry 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M27543 mRNA. Translation: AAA52579.1.
J03005 mRNA. Translation: AAA52557.1.
M20604
, M20597, M20598, M20599, M20600, M20601, M20602, M20603 Genomic DNA. Translation: AAA35895.1.
J03198 mRNA. Translation: AAA35896.1.
J03238 mRNA. Translation: AAA35939.1.
AF493907 mRNA. Translation: AAM12621.1.
BT019973 mRNA. Translation: AAV38776.1.
BT019974 mRNA. Translation: AAV38777.1.
AK312252 mRNA. Translation: BAG35184.1.
CH471122 Genomic DNA. Translation: EAW56393.1.
BC025285 mRNA. Translation: AAH25285.1.
CCDSiCCDS802.1.
PIRiS02348. RGHUI3.
RefSeqiNP_006487.1. NM_006496.3.
UniGeneiHs.73799.
Hs.741171.

Genome annotation databases

EnsembliENST00000369851; ENSP00000358867; ENSG00000065135.
GeneIDi2773.
KEGGihsa:2773.
UCSCiuc001dxz.3. human.

Polymorphism databases

DMDMi120996.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M27543 mRNA. Translation: AAA52579.1 .
J03005 mRNA. Translation: AAA52557.1 .
M20604
, M20597 , M20598 , M20599 , M20600 , M20601 , M20602 , M20603 Genomic DNA. Translation: AAA35895.1 .
J03198 mRNA. Translation: AAA35896.1 .
J03238 mRNA. Translation: AAA35939.1 .
AF493907 mRNA. Translation: AAM12621.1 .
BT019973 mRNA. Translation: AAV38776.1 .
BT019974 mRNA. Translation: AAV38777.1 .
AK312252 mRNA. Translation: BAG35184.1 .
CH471122 Genomic DNA. Translation: EAW56393.1 .
BC025285 mRNA. Translation: AAH25285.1 .
CCDSi CCDS802.1.
PIRi S02348. RGHUI3.
RefSeqi NP_006487.1. NM_006496.3.
UniGenei Hs.73799.
Hs.741171.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2IHB X-ray 2.71 A 32-354 [» ]
2ODE X-ray 1.90 A/C 4-350 [» ]
2V4Z X-ray 2.80 A 4-350 [» ]
4G5O X-ray 2.90 A/B/C/D 25-354 [» ]
4G5R X-ray 3.48 A/B/C/D 25-354 [» ]
4G5S X-ray 3.62 A/B/C/D 25-354 [» ]
ProteinModelPortali P08754.
SMRi P08754. Positions 5-348.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 109035. 59 interactions.
IntActi P08754. 21 interactions.
MINTi MINT-1146232.
STRINGi 9606.ENSP00000358867.

Chemistry

BindingDBi P08754.
ChEMBLi CHEMBL4221.

PTM databases

PhosphoSitei P08754.

Polymorphism databases

DMDMi 120996.

Proteomic databases

MaxQBi P08754.
PaxDbi P08754.
PeptideAtlasi P08754.
PRIDEi P08754.

Protocols and materials databases

DNASUi 2773.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000369851 ; ENSP00000358867 ; ENSG00000065135 .
GeneIDi 2773.
KEGGi hsa:2773.
UCSCi uc001dxz.3. human.

Organism-specific databases

CTDi 2773.
GeneCardsi GC01P110091.
HGNCi HGNC:4387. GNAI3.
HPAi CAB022099.
MIMi 139370. gene.
602483. phenotype.
neXtProti NX_P08754.
Orphaneti 137888. Auriculocondylar syndrome.
PharmGKBi PA173.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG322962.
HOGENOMi HOG000038730.
HOVERGENi HBG063184.
InParanoidi P08754.
KOi K04630.
OMAi GEAARAX.
OrthoDBi EOG72C50B.
PhylomeDBi P08754.
TreeFami TF300673.

Enzyme and pathway databases

Reactomei REACT_15333. Adenylate cyclase inhibitory pathway.
REACT_15426. PLC beta mediated events.
REACT_15457. G-protein activation.
REACT_19231. G alpha (i) signalling events.
REACT_19327. G alpha (s) signalling events.
REACT_19333. G alpha (z) signalling events.
REACT_20653. ADP signalling through P2Y purinoceptor 12.
SignaLinki P08754.

Miscellaneous databases

ChiTaRSi GNAI3. human.
EvolutionaryTracei P08754.
GeneWikii GNAI3.
GenomeRNAii 2773.
NextBioi 10906.
PROi P08754.
SOURCEi Search...

Gene expression databases

ArrayExpressi P08754.
Bgeei P08754.
CleanExi HS_GNAI3.
Genevestigatori P08754.

Family and domain databases

Gene3Di 1.10.400.10. 1 hit.
3.40.50.300. 2 hits.
InterProi IPR001408. Gprotein_alpha_I.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR10218. PTHR10218. 1 hit.
Pfami PF00503. G-alpha. 1 hit.
[Graphical view ]
PRINTSi PR00318. GPROTEINA.
PR00441. GPROTEINAI.
SMARTi SM00275. G_alpha. 1 hit.
[Graphical view ]
SUPFAMi SSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of a new human G protein. Evidence for two Gi alpha-like protein families."
    Didsbury J.R., Snyderman R.
    FEBS Lett. 219:259-263(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "A small multigene family encodes Gi signal-transduction proteins."
    Beals C.R., Wilson C.B., Perlmutter R.M.
    Proc. Natl. Acad. Sci. U.S.A. 84:7886-7890(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs."
    Itoh H., Toyama R., Kozasa T., Tsukamoto T., Matsuoka M., Kaziro Y.
    J. Biol. Chem. 263:6656-6664(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  4. "Alpha i-3 cDNA encodes the alpha subunit of Gk, the stimulatory G protein of receptor-regulated K+ channels."
    Codina J., Olate J., Abramowitz J., Mattera R., Cook R.G., Birnbaumer L.
    J. Biol. Chem. 263:6746-6750(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  5. "Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines."
    Kim S., Ang S.L., Bloch D.B., Bloch K.D., Kawahara Y., Tolman C., Lee R., Seidman J.G., Neer E.J.
    Proc. Natl. Acad. Sci. U.S.A. 85:4153-4157(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  6. "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
    Puhl H.L. III, Ikeda S.R., Aronstam R.S.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  7. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  8. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Liver.
  11. "The human genome encodes at least three non-allelic G proteins with alpha i-type subunits."
    Suki W.N., Abramowitz J., Mattera R., Codina J., Birnbaumer L.
    FEBS Lett. 220:187-192(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 21-354.
  12. "Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division."
    Cho H., Kehrl J.H.
    J. Cell Biol. 178:245-255(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. Cited for: VARIANT ARCND1 ARG-40.

Entry informationi

Entry nameiGNAI3_HUMAN
AccessioniPrimary (citable) accession number: P08754
Secondary accession number(s): P17539, Q5TZX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: January 23, 2007
Last modified: September 3, 2014
This is version 169 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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