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P08745 (COX3_OENBE) Reviewed, UniProtKB/Swiss-Prot

Last modified March 6, 2013. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3
EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Synonyms:COXIII
Encoded onMitochondrion
OrganismOenothera berteriana (Bertero's evening primrose) (Oenothera berteroana)
Taxonomic identifier3950 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Myrtales › Onagraceae › Oenothera

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

mitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Cytochrome c oxidase subunit 3
PRO_0000183815

Regions

Transmembrane16 – 3621Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane84 – 10421Helical; Potential
Transmembrane137 – 15721Helical; Potential
Transmembrane162 – 18221Helical; Potential
Transmembrane200 – 22021Helical; Potential
Transmembrane245 – 26521Helical; Potential

Experimental info

Sequence conflict1021W → R in CAA28459. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P08745 [UniParc].

Last modified November 1, 1995. Version 2.
Checksum: E0C0AF91D9F6E49E

FASTA26529,527
        10         20         30         40         50         60 
MIESQRHSYH LVDPSPWPIS GSLGALATTV GGVMYMHPFQ GGATLLSLGL IFLLYTMFVW 

        70         80         90        100        110        120 
WRDVLRESTL EGHHTKVVQL GLRYGSILFI VSEVMFLFAF FWASSHSSLA PTVEIGGIWP 

       130        140        150        160        170        180 
PKGIGVLDPW EIPFLNTPIL LSSGAAVTWA HHAILAGKEK RAVYALVATV SLAIVFTGFQ 

       190        200        210        220        230        240 
GMEYYQAPPT ISDSIYGSTF YLATGFHGFH VIIGTLFSII CGIRQYLGHL TKEHHVGFEA 

       250        260 
AAWYWHFVDV VRLFLFVSIY WWGGI

« Hide

References

[1]"The cytochrome oxidase subunit I and subunit III genes in Oenothera mitochondria are transcribed from identical promoter sequences."
Hiesel R., Schobel W., Schuster W., Brennicke A.
EMBO J. 6:29-34(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Munzia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X04764 Genomic DNA. Translation: CAA28459.1.
PIROTOB3M. B26170.

3D structure databases

ProteinModelPortalP08745.
SMRP08745. Positions 5-263.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. CytC_oxdse_III. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_OENBE
AccessionPrimary (citable) accession number: P08745
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: November 1, 1995
Last modified: March 6, 2013
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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