ID   HBG4$HUMAN     STANDARD;      PRT;   206 AA.
AC   P08620;
DT   01-AUG-1988  (REL. 08, CREATED)
DT   01-AUG-1988  (REL. 08, LAST SEQUENCE UPDATE)
DT   01-NOV-1990  (REL. 16, LAST ANNOTATION UPDATE)
DE   TRANSFORMING PROTEIN HST/KS3 (HBGF-4) (GENE NAME: HST OR HSTF1 OR
DE   KS3).
OS   HUMAN (HOMO SAPIENS).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA;
OC   EUTHERIA; PRIMATES.
RN   [1] (HST, SEQUENCE FROM N.A.)
RA   YOSHIDA T., MIYAGAWA K., ODAGIRI H., SAKAMOTO H., LITTLE P.F.R.,
RA   TERADA M., SUGIMURA T.;
RL   PROC. NATL. ACAD. SCI. U.S.A. 84:7305-7309(1987).
RN   [2] (SEQUENCE FROM N.A.)
RA   TAIRA M., YOSHIDA T., MIYAGAWA K., SAKAMOTO H., TERADA M.,
RA   SUGIMURA T.;
RL   PROC. NATL. ACAD. SCI. U.S.A. 84:2980-2984(1987).
RN   [3] (KS3, SEQUENCE FROM N.A.)
RA   DELLI BOVI P., CURATOLA A.M., KERN F.G., GRECO A., ITTMANN M.,
RA   BASILICO C.;
RL   CELL 50:729-737(1987).
CC   -!- FUNCTION: HST/KS3 CAN TRANSFORM NIH 3T3 CELLS FROM A HUMAN STOMACH
CC       TUMOR (HST) AND FROM KARPOSI'S SARCOMA (KS3). IT HAS A MITOGENIC
CC       ACTIVITY.
CC   -!- SIMILARITY: BELONGS TO THE HEPARIN-BINDING GROWTH FACTORS FAMILY.
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DR   EMBL; J02986; HSHST.
DR   EMBL; M17446; HSKSGFA.
DR   PIR; A28417; TVHUHS.
DR   PIR; A29876; A29876.
DR   PIR; A29649; A29649.
DR   MIM; 164980; NINTH EDITION.
DR   PROSITE; PS00247; HBGF_FGF.
KW   TRANSFORMING PROTEIN; ONCOGENE; GROWTH FACTOR; MITOGEN.
SQ   SEQUENCE   206 AA;  22047 MW;  227954 CN;
     MSGPGTAAVA LLPAVLLALL APWAGRGGAA APTAPNGTLE AELERRWESL VALSLARLPV
     AAQPKEAAVQ SGAGDYLLGI KRLRRLYCNV GIGFHLQALP DGRIGGAHAD TRDSLLELSP
     VERGVVSIFG VASRFFVAMS SKGKLYGSPF FTDECTFKEI LLPNNYNAYE SYKYPGMFIA
     LSKNGKTKKG NRVSPTMKVT HFLPRL
//