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P08611

- TKN_KASSE

UniProt

P08611 - TKN_KASSE

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Protein

Kassinin

Gene
N/A
Organism
Kassina senegalensis (Senegal running frog)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

GO - Biological processi

  1. defense response Source: UniProtKB-KW
  2. neuropeptide signaling pathway Source: UniProtKB-KW
  3. synaptic transmission Source: InterPro
  4. tachykinin receptor signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Amphibian defense peptide, Neuropeptide

Names & Taxonomyi

Protein namesi
Recommended name:
Kassinin
OrganismiKassina senegalensis (Senegal running frog)
Taxonomic identifieri8415 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaMicrohyloideaHyperoliidaeKassina

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Peptidei1 – 1212KassininPRO_0000044397Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei12 – 121Methionine amide1 Publication

Keywords - PTMi

Amidation

Expressioni

Tissue specificityi

Expressed by the skin glands.

Structurei

Secondary structure

1
12
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi4 – 118Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1MYUNMR-A1-12[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP08611.

Family & Domainsi

Sequence similaritiesi

Belongs to the tachykinin family.Curated

Family and domain databases

InterProiIPR002040. Neurokinin/Substance-P.
IPR013055. Tachy_Neuro_lke_CS.
[Graphical view]
PfamiPF02202. Tachykinin. 1 hit.
[Graphical view]
PROSITEiPS00267. TACHYKININ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P08611-1 [UniParc]FASTAAdd to Basket

« Hide

        10 
DVPKSDQFVG LM
Length:12
Mass (Da):1,336
Last modified:August 1, 1988 - v1
Checksum:i91757AB89DD6DAB5
GO

Sequence databases

PIRiS07206.

Cross-referencesi

Sequence databases

PIRi S07206.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1MYU NMR - A 1-12 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P08611.

Family and domain databases

InterProi IPR002040. Neurokinin/Substance-P.
IPR013055. Tachy_Neuro_lke_CS.
[Graphical view ]
Pfami PF02202. Tachykinin. 1 hit.
[Graphical view ]
PROSITEi PS00267. TACHYKININ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Amino acid composition and sequence of kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis."
    Anastasi A., Montecucchi P.C., Erspamer V., Visser J.
    Experientia 33:857-858(1977) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
    Tissue: Skin secretion.

Entry informationi

Entry nameiTKN_KASSE
AccessioniPrimary (citable) accession number: P08611
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: November 26, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3