P08593 (MSS18_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein MSS18

Gene names

Name:	MSS18
Ordered Locus Names:	YPR134W
ORF Names:	P9659.8

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in splicing of intron aI5-beta of the mitochondrial COX1 transcript. Ref.1
Subcellular location	Mitochondrion Ref.4 Ref.6.
Miscellaneous	Present with 861 molecules/cell in log phase SD medium. Ref.5
Sequence similarities	To baculovirus occlusion-derived virus envelope protein E27 (ODV-E27).

Ontologies

Keywords
Biological process	mRNA processing mRNA splicing
Cellular component	Mitochondrion
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	Group I intron splicing Inferred from mutant phenotype Ref.1. Source: SGD mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrion Inferred from direct assay Ref.6. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 268	268	Protein MSS18		PRO_0000096602

Sequences

	Sequence		Length	Mass (Da)
	P08593 [UniParc]. Last modified August 1, 1988. Version 1. Checksum: 4D0288A25FAF6F4E	FASTA	268	30,957
	10 20 30 40 50 60 MGLPEVNFLR KNCILVELKL FYQTVYPPKE LYWNNRITAE LSTFSNIKYA RPTFAVNNGT 70 80 90 100 110 120 FQRTRPKLDL VLASSDIRKL ATVLFNLKAL IMNTKGEEPT LTTMTSVQTN EEKNDNLEQK 130 140 150 160 170 180 YSSLLDRWNG KVEVHDSPFL QLQRDSNLLF AERPVRYVST TEGEGVDISS EEFFRLEEEQ 190 200 210 220 230 240 CRRNYDVLVD EHSTPSVGMK DGQYGPNIIH FEPSLYHTYS SLPMSMKFWL NGLEDDETTM 250 260 MNIDEKSAEN LDILLHGFKG FSNKRVKG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"MSS18, a yeast nuclear gene involved in the splicing of intron aI5 beta of the mitochondrial cox1 transcript." Seraphin B., Simon M., Faye G. EMBO J. 7:1455-1464(1988) [PubMed: 2842150] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION. Strain: ATCC 204510 / AB320.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]	"The proteome of Saccharomyces cerevisiae mitochondria." Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed: 14576278] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY. Strain: ATCC 76625 / YPH499.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X07650 Genomic DNA. Translation: CAA30490.1. U40829 Genomic DNA. Translation: AAB68275.1. BK006949 Genomic DNA. Translation: DAA11547.1.
PIR	S00553.
RefSeq	NP_015460.1. NM_001184231.1.
3D structure databases
ProteinModelPortal	P08593.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-5396N.
MINT	MINT-485510.
STRING	P08593.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YPR134W; YPR134W; YPR134W.
GeneID	856253.
KEGG	sce:YPR134W.
NMPDR	fig|4932.3.peg.6597.
Organism-specific databases
CYGD	YPR134w.
SGD	S000006338. MSS18.
Phylogenomic databases
OrthoDB	EOG4Q2HRG.
Gene expression databases
ArrayExpress	P08593.
Genevestigator	P08593.
GermOnline	YPR134W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	981534.

Entry information

Entry name

MSS18_YEAST

Accession

Primary (citable) accession number: P08593
Secondary accession number(s): D6W4D1

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1988
Last sequence update:	August 1, 1988
Last modified:	December 14, 2011
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program