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Protein

Colicin V production protein

Gene

cvpA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Required for colicin V production from plasmid IncFI ColV3-K30.

GO - Biological processi

  • toxin biosynthetic process Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG10169-MONOMER.
ECOL316407:JW2310-MONOMER.

Protein family/group databases

TCDBi9.B.160.1.16. the colicin v production (cvpa) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Colicin V production protein
Alternative name(s):
Protein DedE
Pur regulon 18 kDa protein
Gene namesi
Name:cvpA
Synonyms:dedE
Ordered Locus Names:b2313, JW2310
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10169. cvpA.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalSequence analysisAdd BLAST21
Topological domaini22 – 31CytoplasmicSequence analysis10
Transmembranei32 – 52HelicalSequence analysisAdd BLAST21
Topological domaini53 – 63PeriplasmicSequence analysisAdd BLAST11
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Topological domaini85 – 98CytoplasmicSequence analysisAdd BLAST14
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Topological domaini120 – 162PeriplasmicSequence analysisAdd BLAST43

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000795811 – 162Colicin V production proteinAdd BLAST162

Proteomic databases

PaxDbiP08550.
PRIDEiP08550.

Interactioni

Protein-protein interaction databases

BioGridi4260527. 13 interactors.
DIPiDIP-9354N.
IntActiP08550. 1 interactor.
MINTiMINT-1289958.
STRINGi511145.b2313.

Structurei

3D structure databases

ProteinModelPortaliP08550.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E96. Bacteria.
COG1286. LUCA.
HOGENOMiHOG000162044.
InParanoidiP08550.
KOiK03558.
OMAiAPNTDWW.
PhylomeDBiP08550.

Family and domain databases

InterProiIPR003825. Colicin-V_CvpA.
[Graphical view]
PfamiPF02674. Colicin_V. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P08550-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVWIDYAIIA VIAFSSLVSL IRGFVREALS LVTWGCAFFV ASHYYTYLSV
60 70 80 90 100
WFTGFEDELV RNGIAIAVLF IATLIVGAIV NFVIGQLVEK TGLSGTDRVL
110 120 130 140 150
GVCFGALRGV LIVAAILFFL DSFTGVSKSE DWSKSQLIPQ FSFIIRCFFD
160
YLQSSSSFLP RA
Length:162
Mass (Da):17,907
Last modified:August 1, 1988 - v1
Checksum:i856B4216782A837E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01666 Genomic DNA. Translation: AAA24451.1.
M68934 Genomic DNA. Translation: AAA23968.1.
U00096 Genomic DNA. Translation: AAC75373.1.
AP009048 Genomic DNA. Translation: BAA16159.1.
PIRiA29803. XMECED.
RefSeqiNP_416816.1. NC_000913.3.
WP_000262111.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75373; AAC75373; b2313.
BAA16159; BAA16159; BAA16159.
GeneIDi945055.
KEGGiecj:JW2310.
eco:b2313.
PATRICi32119997. VBIEscCol129921_2408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01666 Genomic DNA. Translation: AAA24451.1.
M68934 Genomic DNA. Translation: AAA23968.1.
U00096 Genomic DNA. Translation: AAC75373.1.
AP009048 Genomic DNA. Translation: BAA16159.1.
PIRiA29803. XMECED.
RefSeqiNP_416816.1. NC_000913.3.
WP_000262111.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP08550.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260527. 13 interactors.
DIPiDIP-9354N.
IntActiP08550. 1 interactor.
MINTiMINT-1289958.
STRINGi511145.b2313.

Protein family/group databases

TCDBi9.B.160.1.16. the colicin v production (cvpa) family.

Proteomic databases

PaxDbiP08550.
PRIDEiP08550.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75373; AAC75373; b2313.
BAA16159; BAA16159; BAA16159.
GeneIDi945055.
KEGGiecj:JW2310.
eco:b2313.
PATRICi32119997. VBIEscCol129921_2408.

Organism-specific databases

EchoBASEiEB0167.
EcoGeneiEG10169. cvpA.

Phylogenomic databases

eggNOGiENOG4105E96. Bacteria.
COG1286. LUCA.
HOGENOMiHOG000162044.
InParanoidiP08550.
KOiK03558.
OMAiAPNTDWW.
PhylomeDBiP08550.

Enzyme and pathway databases

BioCyciEcoCyc:EG10169-MONOMER.
ECOL316407:JW2310-MONOMER.

Miscellaneous databases

PROiP08550.

Family and domain databases

InterProiIPR003825. Colicin-V_CvpA.
[Graphical view]
PfamiPF02674. Colicin_V. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCVPA_ECOLI
AccessioniPrimary (citable) accession number: P08550
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: November 2, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.