ID   PHOX_KLULA              Reviewed;         421 AA.
AC   P08540;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 2.
DT   16-JUN-2009, entry version 56.
DE   RecName: Full=Probable acid phosphatase;
DE            EC=3.1.3.2;
GN   OrderedLocusNames=KLLA0B14839g;
OS   Kluyveromyces lactis (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=28985;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37;
RX   MEDLINE=89034156; PubMed=3053697;
RA   Chang Y.-D., Dickson R.C.;
RT   "Primary structure of the lactose permease gene from the yeast
RT   Kluyveromyces lactis. Presence of an unusual transcript structure.";
RL   J. Biol. Chem. 263:16696-16703(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- CATALYTIC ACTIVITY: A phosphate monoester + H(2)O = an alcohol +
CC       phosphate.
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DR   EMBL; X06997; CAA30054.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CR382122; CAH02585.1; -; Genomic_DNA.
DR   PIR; B31776; B31776.
DR   RefSeq; XP_452192.1; -.
DR   GeneID; 2897102; -.
DR   KEGG; kla:KLLA0B14839g; -.
DR   HOGENOM; P08540; -.
DR   OMA; P08540; ISTIEAN.
DR   BRENDA; 3.1.3.2; 74088.
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:EC.
DR   InterPro; IPR007312; Phosphoesterase.
DR   Pfam; PF04185; Phosphoesterase; 1.
PE   4: Predicted;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    421       Probable acid phosphatase.
FT                                /FTId=PRO_0000114473.
FT   ACT_SITE    229    229       Proton donor (By similarity).
SQ   SEQUENCE   421 AA;  47194 MW;  2F7E614C943824E6 CRC64;
     MKFSDFSVLG LGALALNAVT VSANTADTAL LRTYSTISPS LSEIESAASA TEVAEVVSDV
     EGAAFKRFFI IFLENTDYDK AAGDESLSWL AEQGITLTNY WALTHPSEPN YLASVGGDYF
     ALDDDRFISM PSNVSNIVDL LDTKGISWAE YQEHSPYAGF QGMNFSNQET YASDYVRKHN
     PLILFDNVVN NDTRLANIKN FEDFNNDVEN EKLPQYAFIT PNMTNDGHDT TIQFAGKWSK
     DFLAPLLEND YFMEDTLVLL TFDENETYGI KNKVFSILLG GVIPDELKGT KDDTFYDHYS
     QLASVEANWD LPHLGRHDGD ANVLEIVANA TNITNVEVDT TYMINETYIG YLNDYNIELP
     APNVTAINRN GQPILDSIKE TWEDEYSKQV SESYYTSTTT TVSADVTDAE TFSNFYRYRQ
     C
//