Reviewed, UniProtKB/Swiss-Prot P08540 (PHOX_KLULA)

Names and origin

Protein names

Recommended name:
    Probable acid phosphatase
    EC=3.1.3.2

Gene names

Ordered Locus Names:

KLLA0B14839g

Organism

Kluyveromyces lactis (Yeast) (Candida sphaerica) [Complete proteome]

Taxonomic identifier

28985 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces

Protein attributes

Sequence length	421 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 421	421	Probable acid phosphatase		PRO_0000114473
Sites
	Active site	229	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	P08540-1 [UniParc]. Last modified October 1, 1994. Version 2. Checksum: 2F7E614C943824E6	FASTA	421	47,194
	10 20 30 40 50 60 MKFSDFSVLG LGALALNAVT VSANTADTAL LRTYSTISPS LSEIESAASA TEVAEVVSDV 70 80 90 100 110 120 EGAAFKRFFI IFLENTDYDK AAGDESLSWL AEQGITLTNY WALTHPSEPN YLASVGGDYF 130 140 150 160 170 180 ALDDDRFISM PSNVSNIVDL LDTKGISWAE YQEHSPYAGF QGMNFSNQET YASDYVRKHN 190 200 210 220 230 240 PLILFDNVVN NDTRLANIKN FEDFNNDVEN EKLPQYAFIT PNMTNDGHDT TIQFAGKWSK 250 260 270 280 290 300 DFLAPLLEND YFMEDTLVLL TFDENETYGI KNKVFSILLG GVIPDELKGT KDDTFYDHYS 310 320 330 340 350 360 QLASVEANWD LPHLGRHDGD ANVLEIVANA TNITNVEVDT TYMINETYIG YLNDYNIELP 370 380 390 400 410 420 APNVTAINRN GQPILDSIKE TWEDEYSKQV SESYYTSTTT TVSADVTDAE TFSNFYRYRQ C

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Primary structure of the lactose permease gene from the yeast Kluyveromyces lactis. Presence of an unusual transcript structure." Chang Y.-D., Dickson R.C. J. Biol. Chem. 263:16696-16703(1988) [PubMed: 3053697] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37.
[2]	"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X06997 Genomic DNA. Translation: CAA30054.1. Different initiation. CR382122 Genomic DNA. Translation: CAH02585.1.
PIR	B31776.
RefSeq	XP_452192.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2897102.
KEGG	kla:KLLA0B14839g.
Phylogenomic databases
HOGENOM	P08540.
OMA	P08540. ISTIEAN.
Enzyme and pathway databases
BRENDA	3.1.3.2. 74088.
Family and domain databases
InterPro	IPR007312. Phosphoesterase. [Graphical view]
Pfam	PF04185. Phosphoesterase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHOX_KLULA

Accession

Primary (citable) accession number: P08540

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1988
Last sequence update:	October 1, 1994
Last modified:	June 16, 2009
This is version 56 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)