P08523 (OMP_RAT) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 86.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Olfactory marker protein Alternative name(s): Olfactory neuronal-specific protein | ||
| Gene names |
| ||
| Organism | Rattus norvegicus (Rat) [Reference proteome] | ||
| Taxonomic identifier | 10116 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus![]() |
Protein attributes
| Sequence length | 163 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | May act as a modulator of the olfactory signal-transduction cascade. |
| Subunit structure | Interacts with BEX1 and BEX2 By similarity. |
| Subcellular location | |
| Tissue specificity | Uniquely associated with mature olfactory receptor neurons. |
| Sequence similarities | Belongs to the olfactory marker protein family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Olfaction Sensory transduction |
| Cellular component | Cytoplasm |
| PTM | Acetylation |
| Technical term | 3D-structure Complete proteome Direct protein sequencing Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | sensory perception of smell Non-traceable author statement Ref.4. Source: RGD |
| Cellular_component | cytosol Non-traceable author statement Ref.4. Source: RGD |
| Molecular_function | peptide binding Inferred from direct assay Ref.4. Source: RGD signal transducer activityNon-traceable author statement Ref.4. Source: RGD |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |||||||||||||||||||||||||||||||
Molecule processing | ||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Initiator methionine | 1 | 1 | Removed Ref.3 | |||||||||||||||||||||||||||||||||
| Chain | 2 – 163 | 162 | Olfactory marker protein | PRO_0000058046 | ||||||||||||||||||||||||||||||||
Amino acid modifications | ||||||||||||||||||||||||||||||||||||
| Modified residue | 2 | 1 | N-acetylalanine | |||||||||||||||||||||||||||||||||
Secondary structure | ||||||||||||||||||||||||||||||||||||
Helix Strand Turn | ||||||||||||||||||||||||||||||||||||
| Beta strand | 4 – 8 | 5 | ||||||||||||||||||||||||||||||||||
| Helix | 19 – 33 | 15 | ||||||||||||||||||||||||||||||||||
| Turn | 36 – 38 | 3 | ||||||||||||||||||||||||||||||||||
| Beta strand | 53 – 56 | 4 | ||||||||||||||||||||||||||||||||||
| Beta strand | 59 – 62 | 4 | ||||||||||||||||||||||||||||||||||
| Beta strand | 69 – 71 | 3 | ||||||||||||||||||||||||||||||||||
| Beta strand | 73 – 81 | 9 | ||||||||||||||||||||||||||||||||||
| Turn | 89 – 91 | 3 | ||||||||||||||||||||||||||||||||||
| Beta strand | 97 – 99 | 3 | ||||||||||||||||||||||||||||||||||
| Beta strand | 103 – 109 | 7 | ||||||||||||||||||||||||||||||||||
| Turn | 110 – 112 | 3 | ||||||||||||||||||||||||||||||||||
| Beta strand | 113 – 118 | 6 | ||||||||||||||||||||||||||||||||||
| Helix | 119 – 134 | 16 | ||||||||||||||||||||||||||||||||||
| Beta strand | 138 – 144 | 7 | ||||||||||||||||||||||||||||||||||
| Beta strand | 155 – 157 | 3 | ||||||||||||||||||||||||||||||||||
Sequences
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References
| [1] | "Molecular cloning and sequencing of a cDNA for olfactory marker protein." Rogers K.E., Dasgupta P., Gubler U., Grillo M., Khew-Goodall Y.S., Margolis F.L. Proc. Natl. Acad. Sci. U.S.A. 84:1704-1708(1987) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [2] | "Olfactory marker protein gene: its structure and olfactory neuron-specific expression in transgenic mice." Danciger E., Mettling C., Vidal M., Morris R., Margolis F.L. Proc. Natl. Acad. Sci. U.S.A. 86:8565-8569(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. |
| [3] | "Amino acid sequence of a unique neuronal protein: rat olfactory marker protein." Sydor W., Teitelbaum Z., Blacher R., Sun S., Benz W., Margolis F.L. Arch. Biochem. Biophys. 249:351-362(1986) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-163. |
| [4] | "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction." Baldisseri D.M., Margolis J.W., Weber D.J., Koo J.H., Margolis F.L. J. Mol. Biol. 319:823-837(2002) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY NMR. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | M15644 mRNA. Translation: AAA41757.1. M26926 Unassigned DNA. Translation: AAA03054.1. | ||||||||||||||||||
| IPI | IPI00231790. | ||||||||||||||||||
| PIR | A27450. | ||||||||||||||||||
| RefSeq | NP_036748.1. NM_012616.1. | ||||||||||||||||||
| UniGene | Rn.9720. | ||||||||||||||||||
3D structure databases | |||||||||||||||||||
| PDBe RCSB PDB PDBj |
| ||||||||||||||||||
| DisProt | DP00279. | ||||||||||||||||||
| ProteinModelPortal | P08523. | ||||||||||||||||||
| SMR | P08523. Positions 1-163. | ||||||||||||||||||
| ModBase | Search... | ||||||||||||||||||
2D gel databases | |||||||||||||||||||
| World-2DPAGE | 0004:P08523. | ||||||||||||||||||
Proteomic databases | |||||||||||||||||||
| PRIDE | P08523. | ||||||||||||||||||
Protocols and materials databases | |||||||||||||||||||
| StructuralBiologyKnowledgebase | Search... | ||||||||||||||||||
Genome annotation databases | |||||||||||||||||||
| GeneID | 24612. | ||||||||||||||||||
| KEGG | rno:24612. | ||||||||||||||||||
| UCSC | RGD:3231. rat. | ||||||||||||||||||
Organism-specific databases | |||||||||||||||||||
| CTD | 4975. | ||||||||||||||||||
| RGD | 3231. Omp. | ||||||||||||||||||
Phylogenomic databases | |||||||||||||||||||
| HOVERGEN | HBG007595. | ||||||||||||||||||
Gene expression databases | |||||||||||||||||||
| Genevestigator | P08523. | ||||||||||||||||||
Family and domain databases | |||||||||||||||||||
| Gene3D | 2.60.120.390. 1 hit. | ||||||||||||||||||
| InterPro | IPR009103. Olfactory_marker. [Graphical view] | ||||||||||||||||||
| PANTHER | PTHR15357. PTHR15357. 1 hit. | ||||||||||||||||||
| Pfam | PF06554. Olfactory_mark. 1 hit. [Graphical view] | ||||||||||||||||||
| ProDom | PD022055. Olfactory_marker. 1 hit. [Graphical view] [Entries sharing at least one domain] | ||||||||||||||||||
| SUPFAM | SSF63697. Olfactory_marker. 1 hit. | ||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||
Other | |||||||||||||||||||
| EvolutionaryTrace | P08523. | ||||||||||||||||||
| NextBio | 603848. | ||||||||||||||||||
Entry information
| Entry name | OMP_RAT | ||||||||
| Accession | Primary (citable) accession number: P08523 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |

Clusters with
