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Protein

Fructose-bisphosphate aldolase, cytoplasmic isozyme

Gene
N/A
Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei52 – 521Substrate
Binding sitei142 – 1421Substrate
Active sitei183 – 1831Proton acceptorBy similarity
Active sitei225 – 2251Schiff-base intermediate with dihydroxyacetone-P
Sitei355 – 3551Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphate

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

SABIO-RKP08440.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase, cytoplasmic isozyme (EC:4.1.2.13)
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea
ProteomesiUP000007305 Componenti: Unplaced

Organism-specific databases

GrameneiP08440.
MaizeGDBi24903.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 355355Fructose-bisphosphate aldolase, cytoplasmic isozymePRO_0000216921Add
BLAST

Proteomic databases

PRIDEiP08440.
ProMEXiP08440.

Structurei

3D structure databases

ProteinModelPortaliP08440.
SMRiP08440. Positions 9-337.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000220876.
KOiK01623.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR029768. Aldolase_I_AS.
IPR013785. Aldolase_TIM.
IPR029769. FBA_euk-type.
IPR000741. FBA_I.
[Graphical view]
PANTHERiPTHR11627. PTHR11627. 1 hit.
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]
PROSITEiPS00158. ALDOLASE_CLASS_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P08440-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAYCGKYKD ELIKNAAYIG TPGKGILAAD ESTGTIGKRL SSINVENVEE
60 70 80 90 100
NRRALRELLF CCPGALQYIS GVILFEETLY QKTKDGKPFV DVLKEGGVLP
110 120 130 140 150
GIKVDKGTIE VVGTDKETTT QGHDDLGKRC AKYYEAGARF AKWRAVLKIG
160 170 180 190 200
PNEPSQLAID LNAQGLARYA IICQENGLVP IVEPEILVDG PHDIDRCAYV
210 220 230 240 250
TETVLAACYK ALNEHHVLLE GTLLKPNMVT PGSDSKKVTP EVIAEYTVRT
260 270 280 290 300
LQRTVPAAVP AVLFLSGGQS EEEATRNLNA MNKLSTKKPW SLSFSFGRAL
310 320 330 340 350
QASTLKAWAG KVENLEKARA AFLARCKANS EATLGTYKGD AAADTESLHV

KDYKY
Length:355
Mass (Da):38,604
Last modified:August 1, 1988 - v1
Checksum:i54B480978ECD1470
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X12872 Genomic DNA. Translation: CAA31366.1.
M16220 mRNA. Translation: AAA33435.1.
PIRiS07789. ADZM.
RefSeqiNP_001105336.1. NM_001111866.1.
UniGeneiZm.72659.

Genome annotation databases

GeneIDi542261.
KEGGizma:542261.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X12872 Genomic DNA. Translation: CAA31366.1.
M16220 mRNA. Translation: AAA33435.1.
PIRiS07789. ADZM.
RefSeqiNP_001105336.1. NM_001111866.1.
UniGeneiZm.72659.

3D structure databases

ProteinModelPortaliP08440.
SMRiP08440. Positions 9-337.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP08440.
ProMEXiP08440.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi542261.
KEGGizma:542261.

Organism-specific databases

GrameneiP08440.
MaizeGDBi24903.

Phylogenomic databases

HOGENOMiHOG000220876.
KOiK01623.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00183.
SABIO-RKP08440.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR029768. Aldolase_I_AS.
IPR013785. Aldolase_TIM.
IPR029769. FBA_euk-type.
IPR000741. FBA_I.
[Graphical view]
PANTHERiPTHR11627. PTHR11627. 1 hit.
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]
PROSITEiPS00158. ALDOLASE_CLASS_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Anaerobically regulated aldolase gene of maize. A chimaeric origin?"
    Dennis E.S., Gerlach W.L., Walker J.C., Lavin M., Peacock W.J.
    J. Mol. Biol. 202:759-767(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The complete amino acid sequence for the anaerobically induced aldolase from maize derived from cDNA clones."
    Kelley P.M., Tolan D.R.
    Plant Physiol. 82:1076-1080(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiALF_MAIZE
AccessioniPrimary (citable) accession number: P08440
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: May 27, 2015
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.