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P08440 (ALF_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Fructose-bisphosphate aldolase, cytoplasmic isozyme

EC=4.1.2.13
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the class I fructose-bisphosphate aldolase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

response to cadmium ion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to salt stress

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentcytosol

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

mitochondrion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasma membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasmodesma

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functioncopper ion binding

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

fructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 355355Fructose-bisphosphate aldolase, cytoplasmic isozyme
PRO_0000216921

Sites

Active site1831Proton acceptor By similarity
Active site2251Schiff-base intermediate with dihydroxyacetone-P
Binding site521Substrate
Binding site1421Substrate
Site3551Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphate

Sequences

Sequence LengthMass (Da)Tools
P08440 [UniParc].

Last modified August 1, 1988. Version 1.
Checksum: 54B480978ECD1470

FASTA35538,604
        10         20         30         40         50         60 
MSAYCGKYKD ELIKNAAYIG TPGKGILAAD ESTGTIGKRL SSINVENVEE NRRALRELLF 

        70         80         90        100        110        120 
CCPGALQYIS GVILFEETLY QKTKDGKPFV DVLKEGGVLP GIKVDKGTIE VVGTDKETTT 

       130        140        150        160        170        180 
QGHDDLGKRC AKYYEAGARF AKWRAVLKIG PNEPSQLAID LNAQGLARYA IICQENGLVP 

       190        200        210        220        230        240 
IVEPEILVDG PHDIDRCAYV TETVLAACYK ALNEHHVLLE GTLLKPNMVT PGSDSKKVTP 

       250        260        270        280        290        300 
EVIAEYTVRT LQRTVPAAVP AVLFLSGGQS EEEATRNLNA MNKLSTKKPW SLSFSFGRAL 

       310        320        330        340        350 
QASTLKAWAG KVENLEKARA AFLARCKANS EATLGTYKGD AAADTESLHV KDYKY 

« Hide

References

[1]"Anaerobically regulated aldolase gene of maize. A chimaeric origin?"
Dennis E.S., Gerlach W.L., Walker J.C., Lavin M., Peacock W.J.
J. Mol. Biol. 202:759-767(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"The complete amino acid sequence for the anaerobically induced aldolase from maize derived from cDNA clones."
Kelley P.M., Tolan D.R.
Plant Physiol. 82:1076-1080(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X12872 Genomic DNA. Translation: CAA31366.1.
M16220 mRNA. Translation: AAA33435.1.
PIRADZM. S07789.
RefSeqNP_001105336.1. NM_001111866.1.
UniGeneZm.72659.

3D structure databases

ProteinModelPortalP08440.
SMRP08440. Positions 9-337.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP08440.
ProMEXP08440.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID542261.
KEGGzma:542261.

Organism-specific databases

GrameneP08440.
MaizeGDB24903.

Phylogenomic databases

HOGENOMHOG000220876.
KOK01623.

Enzyme and pathway databases

SABIO-RKP08440.
UniPathwayUPA00109; UER00183.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR000741. Aldolase_I.
IPR013785. Aldolase_TIM.
[Graphical view]
PANTHERPTHR11627. PTHR11627. 1 hit.
PfamPF00274. Glycolytic. 1 hit.
[Graphical view]
PROSITEPS00158. ALDOLASE_CLASS_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALF_MAIZE
AccessionPrimary (citable) accession number: P08440
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: July 9, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways