ID   USG_ECOLI               Reviewed;         337 AA.
AC   P08390;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   16-JUN-2009, entry version 73.
DE   RecName: Full=USG-1 protein;
GN   Name=usg; OrderedLocusNames=b2319, JW2316;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   MEDLINE=85269644; PubMed=2991861; DOI=10.1093/nar/13.14.5297;
RA   Arps P.J., Marvel C.C., Rubin B.C., Tolan D.A., Penhoet E.E.,
RA   Winkler M.E.;
RT   "Structural features of the hisT operon of Escherichia coli K-12.";
RL   Nucleic Acids Res. 13:5297-5315(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   MEDLINE=97349980; PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K.,
RA   Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N.,
RA   Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H.,
RA   Oshima T., Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S.,
RA   Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C.,
RA   Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-
RT   K12 genome corresponding to 50.0-68.8 min on the linkage map and
RT   analysis of its sequence features.";
RL   DNA Res. 4:91-113(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA   Mau B., Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1474(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains
RT   MG1655 and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-13 AND 329-337.
RC   STRAIN=K12;
RX   MEDLINE=87137258; PubMed=3029016;
RA   Arps P.J., Winkler M.E.;
RT   "Structural analysis of the Escherichia coli K-12 hisT operon by using
RT   a kanamycin resistance cassette.";
RL   J. Bacteriol. 169:1061-1070(1987).
RN   [6]
RP   PROTEIN SEQUENCE OF 1-27.
RC   STRAIN=K12;
RX   MEDLINE=90036695; PubMed=2681152;
RA   Schoenlein P.V., Roa B.B., Winkler M.E.;
RT   "Divergent transcription of pdxB and homology between the pdxB and
RT   serA gene products in Escherichia coli K-12.";
RL   J. Bacteriol. 171:6084-6092(1989).
CC   -!- INTERACTION:
CC       P0A6K3:def; NbExp=1; IntAct=EBI-548921, EBI-548913;
CC   -!- SIMILARITY: Belongs to the aspartate-semialdehyde dehydrogenase
CC       family.
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DR   EMBL; X02743; CAA26521.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75379.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA16176.1; -; Genomic_DNA.
DR   EMBL; M15541; AAA24311.1; -; Genomic_DNA.
DR   EMBL; M15542; AAA24312.1; -; Genomic_DNA.
DR   EMBL; M29962; AAA24309.1; -; Genomic_DNA.
DR   PIR; A23792; QQECH3.
DR   RefSeq; AP_002919.1; -.
DR   RefSeq; NP_416822.1; -.
DR   DIP; DIP:11095N; -.
DR   IntAct; P08390; 16.
DR   GeneID; 946797; -.
DR   GenomeReviews; AP009048_GR; JW2316.
DR   GenomeReviews; U00096_GR; b2319.
DR   KEGG; ecj:JW2316; -.
DR   KEGG; eco:b2319; -.
DR   EchoBASE; EB1052; -.
DR   EcoGene; EG11059; usg.
DR   HOGENOM; P08390; -.
DR   OMA; P08390; LELWLCG.
DR   BioCyc; EcoCyc:EG11059-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004073; F:aspartate-semialdehyde dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0051287; F:NAD or NADH binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP or NADPH binding; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0008652; P:amino acid biosynthetic process; IEA:InterPro.
DR   InterPro; IPR012080; Asp_semialdehyde_DH.
DR   InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR   InterPro; IPR012280; Semialdhyde_DH_C.
DR   Pfam; PF01118; Semialdhyde_dh; 1.
DR   Pfam; PF02774; Semialdhyde_dhC; 1.
DR   PIRSF; PIRSF000148; ASA_dh; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; Direct protein sequencing.
FT   CHAIN         1    337       USG-1 protein.
FT                                /FTId=PRO_0000141402.
SQ   SEQUENCE   337 AA;  36364 MW;  DF399045C50AE3C5 CRC64;
     MSEGWNIAVL GATGAVGEAL LETLAERQFP VGEIYALARN ESAGEQLRFG GKTITVQDAA
     EFDWTQAQLA FFVAGKEATA AWVEEATNSG CLVIDSSGLF ALEPDVPLVV PEVNPFVLTD
     YRNRNVIAVP DSLTSQLLAA LKPLIDQGGL SRISVTSLIS ASAQGKKAVD ALAGQSAKLL
     NGIPIDEEDF FGRQLAFNML PLLPDSEGSV REERRIVDEV RKILQDEGLM ISASVVQAPV
     FYGHAQMVNF EALRPLAAEE ARDAFVQGED IVLSEENEFP TQVGDASGTP HLSVGCVRND
     YGMPEQVQFW SVADNVRFGG ALMAVKIAEK LVQEYLY
//