USG-1 protein - Escherichia coli (strain K12)

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P08390 (USG_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 97. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
USG-1 protein

Gene names

Name:	usg
Ordered Locus Names:	b2319, JW2316

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family.

Ontologies

Keywords
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	isoleucine biosynthetic process Inferred from electronic annotation. Source: InterPro lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro methionine biosynthetic process Inferred from electronic annotation. Source: InterPro threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro NADP binding Inferred from electronic annotation. Source: InterPro aspartate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: InterPro protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
def	P0A6K3	1	EBI-548921,EBI-548913

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 337

337

USG-1 protein

PRO_0000141402

Sequences

Sequence

Length

Mass (Da)

Tools

P08390 [UniParc].

Last modified August 1, 1988. Version 1.
Checksum: DF399045C50AE3C5
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FASTA

337

36,364

        10         20         30         40         50         60 
MSEGWNIAVL GATGAVGEAL LETLAERQFP VGEIYALARN ESAGEQLRFG GKTITVQDAA 

        70         80         90        100        110        120 
EFDWTQAQLA FFVAGKEATA AWVEEATNSG CLVIDSSGLF ALEPDVPLVV PEVNPFVLTD 

       130        140        150        160        170        180 
YRNRNVIAVP DSLTSQLLAA LKPLIDQGGL SRISVTSLIS ASAQGKKAVD ALAGQSAKLL 

       190        200        210        220        230        240 
NGIPIDEEDF FGRQLAFNML PLLPDSEGSV REERRIVDEV RKILQDEGLM ISASVVQAPV 

       250        260        270        280        290        300 
FYGHAQMVNF EALRPLAAEE ARDAFVQGED IVLSEENEFP TQVGDASGTP HLSVGCVRND 

       310        320        330 
YGMPEQVQFW SVADNVRFGG ALMAVKIAEK LVQEYLY

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural features of the hisT operon of Escherichia coli K-12." Arps P.J., Marvel C.C., Rubin B.C., Tolan D.A., Penhoet E.E., Winkler M.E. Nucleic Acids Res. 13:5297-5315(1985) [PubMed: 2991861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T. Horiuchi T. DNA Res. 4:91-113(1997) [PubMed: 9205837] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]	"Structural analysis of the Escherichia coli K-12 hisT operon by using a kanamycin resistance cassette." Arps P.J., Winkler M.E. J. Bacteriol. 169:1061-1070(1987) [PubMed: 3029016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-13 AND 329-337. Strain: K12.
[6]	"Divergent transcription of pdxB and homology between the pdxB and serA gene products in Escherichia coli K-12." Schoenlein P.V., Roa B.B., Winkler M.E. J. Bacteriol. 171:6084-6092(1989) [PubMed: 2681152] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-27. Strain: K12.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X02743 Genomic DNA. Translation: CAA26521.1. U00096 Genomic DNA. Translation: AAC75379.1. AP009048 Genomic DNA. Translation: BAA16176.1. M15541 Genomic DNA. Translation: AAA24311.1. M15542 Genomic DNA. Translation: AAA24312.1. M29962 Genomic DNA. Translation: AAA24309.1.
PIR	QQECH3. A23792.
RefSeq	NP_416822.1. NC_000913.2.
3D structure databases
ProteinModelPortal	P08390.
SMR	P08390. Positions 2-335.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-11095N.
IntAct	P08390. 16 interactions.
MINT	MINT-1222362.
Proteomic databases
PRIDE	P08390.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000003753; EBESCP00000003753; EBESCG00000003068. EBESCT00000003754; EBESCP00000003754; EBESCG00000003068. EBESCT00000015858; EBESCP00000015149; EBESCG00000014918.
GeneID	946797.
GenomeReviews	Gene locus JW2316 in contig AP009048_GR. Gene locus b2319 in contig U00096_GR.
KEGG	ecj:JW2316. eco:b2319.
PATRIC	32120009. VBIEscCol129921_2414.
Organism-specific databases
EchoBASE	EB1052.
EcoGene	EG11059. usg.
Phylogenomic databases
eggNOG	COG0136.
GeneTree	EBGT00050000011013.
HOGENOM	HBG518238.
OMA	LELWLCG.
PhylomeDB	P08390.
ProtClustDB	PRK08040.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11059-MONOMER.
Gene expression databases
Genevestigator	P08390.
Family and domain databases
InterPro	IPR012080. Asp_semialdehyde_DH. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00133.
Pfam	PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view]
PIRSF	PIRSF000148. ASA_dh. 1 hit.
SMART	SM00859. Semialdhyde_dh. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

USG_ECOLI

Accession

Primary (citable) accession number: P08390

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1988
Last sequence update:	August 1, 1988
Last modified:	January 25, 2012
This is version 97 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

Sequence annotation (Features)

Molecule processing

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents