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Protein

Pathogenesis-related protein 1A

Gene
N/A
Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Probably involved in the defense reaction of plants against pathogens.

GO - Biological processi

Keywordsi

Molecular functionPathogenesis-related protein
Biological processPlant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Pathogenesis-related protein 1A
Short name:
PR-1A
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Subcellular locationi

  • Vacuole 1 Publication

  • Note: Accumulates in within the vacuoles of specialized cells known as crystal idioblasts.

GO - Cellular componenti

Keywords - Cellular componenti

Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Add BLAST30
ChainiPRO_000000630031 – 168Pathogenesis-related protein 1AAdd BLAST138

Post-translational modificationi

Three disulfide bonds are present.By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Inductioni

Synthesized during pathogen infection or other stress-related responses.

Structurei

3D structure databases

ProteinModelPortaliP08299.
SMRiP08299.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 156SCPAdd BLAST119

Sequence similaritiesi

Belongs to the CRISP family.Curated

Keywords - Domaini

Signal

Family and domain databases

CDDicd05381. SCP_PR-1_like. 1 hit.
Gene3Di3.40.33.10. 1 hit.
InterProiView protein in InterPro
IPR001283. Allrgn_V5/Tpx1.
IPR018244. Allrgn_V5/Tpx1_CS.
IPR014044. CAP_domain.
IPR034111. SCP_PR1-like.
IPR002413. V5_allergen.
PANTHERiPTHR10334. PTHR10334. 1 hit.
PfamiView protein in Pfam
PF00188. CAP. 1 hit.
PRINTSiPR00838. V5ALLERGEN.
PR00837. V5TPXLIKE.
SMARTiView protein in SMART
SM00198. SCP. 1 hit.
SUPFAMiSSF55797. SSF55797. 1 hit.
PROSITEiView protein in PROSITE
PS01009. CRISP_1. 1 hit.
PS01010. CRISP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P08299-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFVLFSQLP SFLLVSTLLL FLVISHSCRA QNSQQDYLDA HNTARADVGV
60 70 80 90 100
EPLTWDDQVA AYAQNYASQL AADCNLVHSH GQYGENLAEG SGDFMTAAKA
110 120 130 140 150
VEMWVDEKQY YDHDSNTCAQ GQVCGHYTQV VWRNSVRVGC ARVQCNNGGY
160
VVSCNYDPPG NYRGESPY
Length:168
Mass (Da):18,574
Last modified:August 1, 1988 - v1
Checksum:i27375217031292E0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti5 – 6LF → VS in CAA31008 (PubMed:3186451).Curated2
Sequence conflicti57D → S AA sequence (PubMed:16453639).Curated1
Sequence conflicti68 – 69SQ → PS AA sequence (PubMed:16453639).Curated2
Sequence conflicti106D → N in CAA30017 (Ref. 3) Curated1
Sequence conflicti153S → T in CAA30017 (Ref. 3) Curated1
Sequence conflicti162Y → W AA sequence (PubMed:16453639).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05959 Genomic DNA. Translation: CAA29392.1.
X06361 Genomic DNA. Translation: CAA29660.1.
X12485 mRNA. Translation: CAA31008.1.
X06930 Genomic DNA. Translation: CAA30017.1.
PIRiA05264.
A24620.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05959 Genomic DNA. Translation: CAA29392.1.
X06361 Genomic DNA. Translation: CAA29660.1.
X12485 mRNA. Translation: CAA31008.1.
X06930 Genomic DNA. Translation: CAA30017.1.
PIRiA05264.
A24620.

3D structure databases

ProteinModelPortaliP08299.
SMRiP08299.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd05381. SCP_PR-1_like. 1 hit.
Gene3Di3.40.33.10. 1 hit.
InterProiView protein in InterPro
IPR001283. Allrgn_V5/Tpx1.
IPR018244. Allrgn_V5/Tpx1_CS.
IPR014044. CAP_domain.
IPR034111. SCP_PR1-like.
IPR002413. V5_allergen.
PANTHERiPTHR10334. PTHR10334. 1 hit.
PfamiView protein in Pfam
PF00188. CAP. 1 hit.
PRINTSiPR00838. V5ALLERGEN.
PR00837. V5TPXLIKE.
SMARTiView protein in SMART
SM00198. SCP. 1 hit.
SUPFAMiSSF55797. SSF55797. 1 hit.
PROSITEiView protein in PROSITE
PS01009. CRISP_1. 1 hit.
PS01010. CRISP_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPR1A_TOBAC
AccessioniPrimary (citable) accession number: P08299
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: February 15, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.