Reviewed, UniProtKB/Swiss-Prot P08287 (H11L_CHICK)

Names and origin

Protein names	Recommended name:     Histone H1.11L
Organism	Gallus gallus (Chicken)
Taxonomic identifier	9031 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	225 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.
Subcellular location	Nucleus.
Sequence similarities	Belongs to the histone H1/H5 family.

Ontologies

Keywords
Cellular component	Chromosomal protein Nucleus
Ligand	DNA-binding
PTM	Acetylation
Technical term	3D-structure
Gene Ontology (GO)
Biological process	nucleosome assembly Inferred from electronic annotation. Source: InterPro
Cellular component	nucleosome Inferred from electronic annotation. Source: InterPro nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

1

1

Removed

Chain

2 – 225

224

Histone H1.11L

PRO_0000195931

Regions

Region

41 – 114

74

Globular

Amino acid modifications

Modified residue

2

1

N-acetylserine By similarity

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

225

Helix Strand Turn

Details...

Beta strand

41 – 43

3

Helix

44 – 54

11

Beta strand

56 – 59

4

Helix

66 – 68

3

Beta strand

69 – 74

6

Beta strand

77 – 80

4

Helix

81 – 87

7

Turn

88 – 90

3

Helix

91 – 94

4

Sequences

	Sequence		Length	Mass (Da)
	P08287-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: BFDA6897A7D5599F	FASTA	225	22,528
	10 20 30 40 50 60 MSETAPAPAA EAAPAAAPAP AKAAAKKPKK AAGGAKARKP AGPSVTELIT KAVSASKERK 70 80 90 100 110 120 GLSLAALKKA LAAGGYDVEK NNSRIKLGLK SLVSKGTLVQ TKGTGASGSF RLSKKPGEVK 130 140 150 160 170 180 EKAPKKKASA AKPKKPAAKK PAAAAKKPKK AVAVKKSPKK AKKPAASATK KSAKSPKKVT 190 200 210 220 KAVKPKKAVA AKSPAKAKAV KPKAAKPKAA KPKAAKAKKA AAKKK

References

[1]	"Characterization of the chicken histone H1 gene complement. Generation of a complete set of vertebrate H1 protein sequences." Coles L.S., Robins A.J., Madley L.K., Wells J.R.E. J. Biol. Chem. 262:9656-9663(1987) [PubMed: 3597432] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: sequential assignment and secondary structure." Cerf C., Lippens G., Muyldermans S., Segers A., Ramakrishnan V., Wodak S.J., Hallenga K., Wyns L. Biochemistry 32:11345-11351(1993) [PubMed: 8218199] [Abstract] Cited for: STRUCTURE BY NMR OF 41-114.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

M17019 Genomic DNA. Translation: AAA48789.1.

IPI

IPI00581595.

PIR

B28456.

RefSeq

NP_001035733.1.

UniGene

Gga.41653

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1GHC	NMR	-	A	41-113	[»]

ModBase

Search...

Protein-protein interaction databases

STRING

P08287.

Genome annotation databases

Ensembl

ENSGALT00000038058; ENSGALP00000037266; ENSGALG00000011759; Gallus gallus. [Genome view]

GeneID

427892.

KEGG

gga:427892.

Organism-specific databases

CTD

427892.

Phylogenomic databases

HOGENOM

HBG446956.

HOVERGEN

P08287.

InParanoid

P08287.

OMA

VKPKKAV.

Family and domain databases

InterPro

IPR005818. Histone_H1/H5.
IPR005819. Histone_H5.
IPR011991. WHTH_trsnscrt_rep_DNA-bd.
[Graphical view]

Gene3D

G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.

Pfam

PF00538. Linker_histone. 1 hit.
[Graphical view]

PRINTS

PR00624. HISTONEH5.

SMART

SM00526. H15. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

H11L_CHICK

Accession

Primary (citable) accession number: P08287

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1988
Last sequence update:	January 23, 2007
Last modified:	February 9, 2010
This is version 74 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)