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Protein

Protein FimG

Gene

fimG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei166Required for stability and transportBy similarity1

GO - Biological processi

Enzyme and pathway databases

BioCyciEcoCyc:EG10314-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FimG
Gene namesi
Name:fimG
Ordered Locus Names:b4319, JW4282
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10314 fimG

Subcellular locationi

GO - Cellular componenti

  • pilus Source: UniProtKB-SubCell

Keywords - Cellular componenti

Fimbrium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000000921024 – 167Protein FimGAdd BLAST144

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi39 ↔ 77Curated

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP08190
PRIDEiP08190

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
fimCP316975EBI-1785843,EBI-1028005

Protein-protein interaction databases

BioGridi4262750, 9 interactors
DIPiDIP-9615N
IntActiP08190, 1 interactor
STRINGi316407.85677062

Structurei

Secondary structure

1167
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi26 – 34Combined sources9
Beta strandi40 – 42Combined sources3
Beta strandi44 – 53Combined sources10
Helixi55 – 57Combined sources3
Beta strandi68 – 75Combined sources8
Beta strandi83 – 89Combined sources7
Beta strandi96 – 99Combined sources4
Beta strandi108 – 112Combined sources5
Beta strandi114 – 116Combined sources3
Beta strandi124 – 128Combined sources5
Turni131 – 134Combined sources4
Beta strandi135 – 145Combined sources11
Beta strandi147 – 149Combined sources3
Beta strandi153 – 166Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BFQX-ray1.34G36-167[»]
3BFWX-ray1.80A/C36-167[»]
3JWNX-ray2.69G/M24-167[»]
4J3OX-ray3.80G24-167[»]
4XO9X-ray1.14B24-37[»]
4XOAX-ray2.54B/D/F/H24-37[»]
4XODX-ray1.14B24-37[»]
5IQMX-ray1.50A/G36-167[»]
5IQNX-ray1.00A/G36-167[»]
5IQOX-ray1.30A/C36-167[»]
ProteinModelPortaliP08190
SMRiP08190
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP08190

Family & Domainsi

Sequence similaritiesi

Belongs to the fimbrial protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108T65 Bacteria
ENOG4111FMS LUCA
HOGENOMiHOG000260127
InParanoidiP08190
KOiK07349
OMAiQAVISVT
PhylomeDBiP08190

Family and domain databases

Gene3Di2.60.40.1090, 1 hit
InterProiView protein in InterPro
IPR036937 Adhesion_dom_fimbrial_sf
IPR008966 Adhesion_dom_sf
SUPFAMiSSF49401 SSF49401, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P08190-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWCKRGYVL AAILALASAT IQAADVTITV NGKVVAKPCT VSTTNATVDL
60 70 80 90 100
GDLYSFSLMS AGAASAWHDV ALELTNCPVG TSRVTASFSG AADSTGYYKN
110 120 130 140 150
QGTAQNIQLE LQDDSGNTLN TGATKTVQVD DSSQSAHFPL QVRALTVNGG
160
ATQGTIQAVI SITYTYS
Length:167
Mass (Da):17,317
Last modified:February 1, 1995 - v2
Checksum:i8C3EF95FD442E22C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti61A → S in CAA29155 (PubMed:2890081).Curated1
Sequence conflicti148 – 149NG → KV in CAA29155 (PubMed:2890081).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05672 Genomic DNA Translation: CAA29155.1
U14003 Genomic DNA Translation: AAA97215.1
U00096 Genomic DNA Translation: AAC77275.1
AP009048 Genomic DNA Translation: BAE78312.1
PIRiS56544
RefSeqiNP_418739.1, NC_000913.3
WP_000870592.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77275; AAC77275; b4319
BAE78312; BAE78312; BAE78312
GeneIDi948846
KEGGiecj:JW4282
eco:b4319
PATRICifig|1411691.4.peg.2373

Similar proteinsi

Entry informationi

Entry nameiFIMG_ECOLI
AccessioniPrimary (citable) accession number: P08190
Secondary accession number(s): Q2M5Z4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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