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Protein

Esterase-6

Gene

Est-6

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transferred from the ejaculatory bulbs of males to the female genitals upon copulation, plays an important role in the reproductive biology.

Catalytic activityi

A carboxylic ester + H2O = an alcohol + a carboxylate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei209Acyl-ester intermediatePROSITE-ProRule annotation1
Active sitei466Charge relay systemBy similarity1

GO - Molecular functioni

GO - Biological processi

  • courtship behavior Source: FlyBase
  • mating Source: FlyBase
  • modulation of synaptic transmission Source: GO_Central
  • multicellular organism reproduction Source: FlyBase
  • neuron cell-cell adhesion Source: GO_Central
  • ovulation Source: FlyBase
  • pheromone biosynthetic process Source: FlyBase
  • regulation of female receptivity, post-mating Source: FlyBase
  • regulation of oviposition Source: FlyBase
  • sperm storage Source: FlyBase
  • synapse assembly Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Serine esterase

Protein family/group databases

ESTHERidrome-este6. Carb_B_Arthropoda.
MEROPSiS09.947.

Names & Taxonomyi

Protein namesi
Recommended name:
Esterase-6 (EC:3.1.1.1)
Short name:
Est-6
Alternative name(s):
Carboxylic-ester hydrolase 6
Short name:
Carboxylesterase-6
Gene namesi
Name:Est-6
Synonyms:EST6
ORF Names:CG6917
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0000592. Est-6.

Subcellular locationi

GO - Cellular componenti

  • cell surface Source: GO_Central
  • extracellular space Source: FlyBase
  • integral component of plasma membrane Source: GO_Central
  • synapse Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Add BLAST21
ChainiPRO_000000856122 – 544Esterase-6Add BLAST523

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi42N-linked (GlcNAc...)1 Publication1
Disulfide bondi86 ↔ 105By similarity
Disulfide bondi261 ↔ 273By similarity
Glycosylationi420N-linked (GlcNAc...)1 Publication1
Glycosylationi456N-linked (GlcNAc...)1 Publication1
Glycosylationi506N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi514 ↔ 535Sequence analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiP08171.
PRIDEiP08171.

Expressioni

Tissue specificityi

Specifically expressed in the ejaculatory bulbs of male.

Gene expression databases

BgeeiFBgn0000592.
ExpressionAtlasiP08171. baseline.
GenevisibleiP08171. DM.

Interactioni

Subunit structurei

Monomer.

GO - Molecular functioni

Protein-protein interaction databases

BioGridi64746. 1 interactor.
DIPiDIP-21801N.
IntActiP08171. 1 interactor.
MINTiMINT-293517.
STRINGi7227.FBpp0305575.

Structurei

3D structure databases

ProteinModelPortaliP08171.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1516. Eukaryota.
COG2272. LUCA.
GeneTreeiENSGT00680000100015.
InParanoidiP08171.
KOiK01044.
OMAiIVLSCLW.
OrthoDBiEOG091G046C.
PhylomeDBiP08171.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
[Graphical view]
PfamiPF00135. COesterase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P08171-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYVGLGLII VLSCLWLGSN ASDTDDPLLV QLPQGKLRGR DNGSYYSYES
60 70 80 90 100
IPYAEPPTGD LRFEAPEPYK QKWSDIFDAT KTPVACLQWD QFTPGANKLV
110 120 130 140 150
GEEDCLTVSV YKPKNSKRNS FPVVAHIHGG AFMFGAAWQN GHENVMREGK
160 170 180 190 200
FILVKISYRL GPLGFVSTGD RDLPGNYGLK DQRLALKWIK QNIASFGGEP
210 220 230 240 250
QNVLLVGHSA GGASVHLQML REDFGQLARA AFSFSGNALD PWVIQKGARG
260 270 280 290 300
RAFELGRNVG CESAEDSTSL KKCLKSKPAS ELVTAVRKFL IFSYVPFAPF
310 320 330 340 350
SPVLEPSDAP DAIITQDPRD VIKSGKFGQV PWAVSYVTED GGYNAALLLK
360 370 380 390 400
ERKSGIVIDD LNERWLELAP YLLFYRDTKT KKDMDDYSRK IKQEYIGNQR
410 420 430 440 450
FDIESYSELQ RLFTDILFKN STQESLDLHR KYGKSPAYAY VYDNPAEKGI
460 470 480 490 500
AQVLANRTDY DFGTVHGDDY FLIFENFVRD VEMRPDEQII SRNFINMLAD
510 520 530 540
FASSDNGSLK YGECDFKDNV GSEKFQLLAI YIDGCQNRQH VEFP
Length:544
Mass (Da):61,125
Last modified:November 1, 1990 - v2
Checksum:i5D99B80DF588F268
GO

Sequence cautioni

The sequence AAM11419 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti519N → S in AAA28517 (PubMed:3106966).Curated1
Sequence conflicti534 – 544GCQNRQHVEFP → AARIGSMWNFRKLHE in AAA28517 (PubMed:3106966).CuratedAdd BLAST11

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti10I → T in strain: 178.7, 357F, 517S, Bar-F-77F, Bar-F-79F, Bar-F-96S, DPF-13, DPF-30, DPF-82.1, EM-10, F-274F, F-517F, F-1461S, MA-4.4 and Zim-F-H31. 1
Natural varianti24T → I in strain: 178.7, 377F, 357F, 517S, Bar-F-79F, DPF-13, DPF-30, DPF-82.1, EM-10, F-274F, F-517F, F-775F, F-1461S, MA-4.4, Ven-S-13F, Zim-F-H27, Zim-F-H31, Zim-F-S11, Zim-F-S18, Zim-F-S53, Zim-S-S2, Zim-S-S30 and Zim-S-S34. 1
Natural varianti33P → S in strain: Zim-S-H13. 1
Natural varianti58T → I in strain: 178.7, 357F, 517S, Bar-F-77F, Bar-F-79F, Bar-F-96S, DPF-13, DPF-30, DPF-82.1, EM-10, F-274F, F-1461S, MA-4.2, VC-805, Ven-S-1F, Ven-S-2F, Ven-S-3F, Ven-S-11F, Ven-S-21F, Zim-F-H31, Zim-F-S18 and Zim-S-S10. 1
Natural varianti120S → T in strain: DPF-2 and 521S. 1
Natural varianti258N → D in strain: 178.7, 357F, 517S, 709.6, Bar-F-7F, Bar-F-77F, Bar-F-79F, Bar-F-93F, Bar-F-96S, DPF-13, DPF-30, DPF-46, DPF-77, DPF-82.1, EM-10, F-96S, F-274F, F-517F, F-531F, F-611F, F-775F, F-1461S, MA-4.2, Zim-F-H27, Zim-F-H31, Zim-F-S11, Zim-F-S18 and Zim-F-S53. 1
Natural varianti268T → A in strain: 174F, 178.7, 357F, 517S, 709.6, Bar-F-7F, Bar-F-77F, Bar-F-79F, Bar-F-93F, Bar-F-96S, Bar-S-24F, Bar-S-60F, Bar-S-78F, Bar-S-89F, Bar-S-99F, Bar-S-95F, DPF-13, DPF-30, DPF-46, DPF-77, DPF-82.1, EM-10, F-96S, F-274F, F-517F, F-531F, S-549S, F-611F, F-775F, F-1461S, MA-4.2, S-114S, S-2588S, VC-815, Ven-S-1F, Ven-S-2F, Ven-S-3F, Ven-S-4F, Ven-S-11F, Ven-S-21F, Zim-F-H27, Zim-F-H31, Zim-F-S11, Zim-F-S18, Zim-F-S53, Zim-S-S34 and Zim-S-44F. 1
Natural varianti276S → P in strain: VC-805. 1
Natural varianti309A → V in strain: Ven-S-13F. 1
Natural varianti356I → T in strain: F-775F. 1
Natural varianti363E → D in strain: F-775F. 1
Natural varianti371Y → H in strain: F-775F. 1
Natural varianti376R → G in strain: Zim-S-S34. 1
Natural varianti394E → D in strain: Ven-S-13F and Zim-F-S18. 1
Natural varianti397G → R in strain: US-255F. 1
Natural varianti409L → V in strain: 357F, 517S, Bar-F-7F, Bar-F-77F, Bar-F-79F, Bar-F-93F, Bar-F-96S, DPF-13, DPF-30, F-96S, F-274F, F-517F, F-1461S, S-114S, S-549S, S-2588S, VC-805, Ven-S-4F, Zim-S-S2, Zim-S-S30 and Zim-S-S34. 1
Natural varianti441V → I in strain: Zim-F-S53. 1
Natural varianti492R → K in strain: 94F, 174F, Bar-S-24F, Bar-S-89F, Bar-S-99F, Bar-S-95F, Bar-S-60F, F-531F, F-611F, MA-4.2, Zim-F-H27, Zim-F-S18 and Zim-S-44F. 1
Natural varianti500D → N in strain: Zim-F-S18, Zim-S-H32 and Zim-S-S2. 1
Natural varianti508S → A in strain: 357F, 517S, Bar-F-79F, Bar-S-78F, DPF-13, DPF-30, F-96S, F-517F, F-1461S, MA-4.2, VC-805, Ven-S-1F, Ven-S-2F, Ven-S-3F, Ven-S-11F, Ven-S-21F and Zim-F-S11. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33780 Genomic DNA. Translation: AAA28519.1.
J04167 Genomic DNA. Translation: AAA28518.1.
M15961 mRNA. Translation: AAA28517.1.
AF147095 Genomic DNA. Translation: AAD39958.1.
AF147096 Genomic DNA. Translation: AAD39959.1.
AF147097 Genomic DNA. Translation: AAD39960.1.
AF147098 Genomic DNA. Translation: AAD39961.1.
AF147099 Genomic DNA. Translation: AAD39962.1.
AF147100 Genomic DNA. Translation: AAD39963.1.
AF147101 Genomic DNA. Translation: AAD39964.1.
AF147102 Genomic DNA. Translation: AAD39965.1.
AF217624 Genomic DNA. Translation: AAF61043.1.
AF217625 Genomic DNA. Translation: AAF61044.1.
AF217626 Genomic DNA. Translation: AAF61045.1.
AF217627 Genomic DNA. Translation: AAF61046.1.
AF217628 Genomic DNA. Translation: AAF61047.1.
AF217629 Genomic DNA. Translation: AAF61048.1.
AF217630 Genomic DNA. Translation: AAF61049.1.
AF217631 Genomic DNA. Translation: AAF61050.1.
AF217632 Genomic DNA. Translation: AAF61051.1.
AF217633 Genomic DNA. Translation: AAF61052.1.
AF217634 Genomic DNA. Translation: AAF61053.1.
AF217635 Genomic DNA. Translation: AAF61054.1.
AF217636 Genomic DNA. Translation: AAF61055.1.
AF217637 Genomic DNA. Translation: AAF61056.1.
AF217638 Genomic DNA. Translation: AAF61057.1.
AF217639 Genomic DNA. Translation: AAF61058.1.
AF217640 Genomic DNA. Translation: AAF61059.1.
AF217641 Genomic DNA. Translation: AAF61060.1.
AF217642 Genomic DNA. Translation: AAF61061.1.
AF217643 Genomic DNA. Translation: AAF61062.1.
AF217644 Genomic DNA. Translation: AAF61063.1.
AF217645 Genomic DNA. Translation: AAF61064.1.
AY247664 Genomic DNA. Translation: AAP20953.1.
AY247665 Genomic DNA. Translation: AAP20954.1.
AY247666 Genomic DNA. Translation: AAP20955.1.
AY247667 Genomic DNA. Translation: AAP20956.1.
AY247668 Genomic DNA. Translation: AAP20957.1.
AY247669 Genomic DNA. Translation: AAP20958.1.
AY247670 Genomic DNA. Translation: AAP20959.1.
AY247671 Genomic DNA. Translation: AAP20960.1.
AY247672 Genomic DNA. Translation: AAP20961.1.
AY247673 Genomic DNA. Translation: AAP20962.1.
AY247674 Genomic DNA. Translation: AAP20963.1.
AY247675 Genomic DNA. Translation: AAP20964.1.
AY247676 Genomic DNA. Translation: AAP20965.1.
AY247677 Genomic DNA. Translation: AAP20966.1.
AY247678 Genomic DNA. Translation: AAP20967.1.
AY247679 Genomic DNA. Translation: AAP20968.1.
AY247680 Genomic DNA. Translation: AAP20969.1.
AY247681 Genomic DNA. Translation: AAP20970.1.
AY247682 Genomic DNA. Translation: AAP20971.1.
AY247683 Genomic DNA. Translation: AAP20972.1.
AY247684 Genomic DNA. Translation: AAP20973.1.
AY247685 Genomic DNA. Translation: AAP20974.1.
AY247686 Genomic DNA. Translation: AAP20975.1.
AY247687 Genomic DNA. Translation: AAP20976.1.
AY247688 Genomic DNA. Translation: AAP20977.1.
AY247689 Genomic DNA. Translation: AAP20978.1.
AY247690 Genomic DNA. Translation: AAP20979.1.
AY247691 Genomic DNA. Translation: AAP20980.1.
AY247692 Genomic DNA. Translation: AAP20981.1.
AY247693 Genomic DNA. Translation: AAP20982.1.
AY247694 Genomic DNA. Translation: AAP20983.1.
AY247695 Genomic DNA. Translation: AAP20984.1.
AY247696 Genomic DNA. Translation: AAP20985.1.
AY247697 Genomic DNA. Translation: AAP20986.1.
AY247698 Genomic DNA. Translation: AAP20987.1.
AY247699 Genomic DNA. Translation: AAP20988.1.
AY247700 Genomic DNA. Translation: AAP20989.1.
AY247701 Genomic DNA. Translation: AAP20990.1.
AY247702 Genomic DNA. Translation: AAP20991.1.
AY247703 Genomic DNA. Translation: AAP20992.1.
AY247704 Genomic DNA. Translation: AAP20993.1.
AY247705 Genomic DNA. Translation: AAP20994.1.
AY247706 Genomic DNA. Translation: AAP20995.1.
AY247707 Genomic DNA. Translation: AAP20996.1.
AY247708 Genomic DNA. Translation: AAP20997.1.
AY247709 Genomic DNA. Translation: AAP20998.1.
AY247710 Genomic DNA. Translation: AAP20999.1.
AY247711 Genomic DNA. Translation: AAP21000.1.
AY247712 Genomic DNA. Translation: AAP21001.1.
AY247713 Genomic DNA. Translation: AAP21002.1.
AE014296 Genomic DNA. Translation: AAF49946.1.
AY095091 mRNA. Translation: AAM11419.1. Sequence problems.
U57474 Genomic DNA. Translation: AAB46692.1.
U57475 Genomic DNA. Translation: AAB46693.1.
U57476 Genomic DNA. Translation: AAB46694.1.
U57477 Genomic DNA. Translation: AAB46695.1.
U57478 Genomic DNA. Translation: AAB46696.1.
U57479 Genomic DNA. Translation: AAB46697.1.
U57480 Genomic DNA. Translation: AAB46698.1.
U57481 Genomic DNA. Translation: AAB46699.1.
U57482 Genomic DNA. Translation: AAB46700.1.
U57483 Genomic DNA. Translation: AAB46701.1.
U57484 Genomic DNA. Translation: AAB46702.1.
U57485 Genomic DNA. Translation: AAB46703.1.
U57486 Genomic DNA. Translation: AAB46704.1.
U57487 Genomic DNA. Translation: AAB46705.1.
U57488 Genomic DNA. Translation: AAB46706.1.
PIRiA28022.
A34089.
A40122.
A41426.
B40122.
B41426.
C41426.
D41426.
E41426.
F41426.
G41426.
H41426.
I41426.
RefSeqiNP_001261749.1. NM_001274820.1.
NP_788500.1. NM_176322.3.
UniGeneiDm.2828.

Genome annotation databases

EnsemblMetazoaiFBtr0076003; FBpp0075735; FBgn0000592.
FBtr0333383; FBpp0305575; FBgn0000592.
GeneIDi39392.
KEGGidme:Dmel_CG6917.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33780 Genomic DNA. Translation: AAA28519.1.
J04167 Genomic DNA. Translation: AAA28518.1.
M15961 mRNA. Translation: AAA28517.1.
AF147095 Genomic DNA. Translation: AAD39958.1.
AF147096 Genomic DNA. Translation: AAD39959.1.
AF147097 Genomic DNA. Translation: AAD39960.1.
AF147098 Genomic DNA. Translation: AAD39961.1.
AF147099 Genomic DNA. Translation: AAD39962.1.
AF147100 Genomic DNA. Translation: AAD39963.1.
AF147101 Genomic DNA. Translation: AAD39964.1.
AF147102 Genomic DNA. Translation: AAD39965.1.
AF217624 Genomic DNA. Translation: AAF61043.1.
AF217625 Genomic DNA. Translation: AAF61044.1.
AF217626 Genomic DNA. Translation: AAF61045.1.
AF217627 Genomic DNA. Translation: AAF61046.1.
AF217628 Genomic DNA. Translation: AAF61047.1.
AF217629 Genomic DNA. Translation: AAF61048.1.
AF217630 Genomic DNA. Translation: AAF61049.1.
AF217631 Genomic DNA. Translation: AAF61050.1.
AF217632 Genomic DNA. Translation: AAF61051.1.
AF217633 Genomic DNA. Translation: AAF61052.1.
AF217634 Genomic DNA. Translation: AAF61053.1.
AF217635 Genomic DNA. Translation: AAF61054.1.
AF217636 Genomic DNA. Translation: AAF61055.1.
AF217637 Genomic DNA. Translation: AAF61056.1.
AF217638 Genomic DNA. Translation: AAF61057.1.
AF217639 Genomic DNA. Translation: AAF61058.1.
AF217640 Genomic DNA. Translation: AAF61059.1.
AF217641 Genomic DNA. Translation: AAF61060.1.
AF217642 Genomic DNA. Translation: AAF61061.1.
AF217643 Genomic DNA. Translation: AAF61062.1.
AF217644 Genomic DNA. Translation: AAF61063.1.
AF217645 Genomic DNA. Translation: AAF61064.1.
AY247664 Genomic DNA. Translation: AAP20953.1.
AY247665 Genomic DNA. Translation: AAP20954.1.
AY247666 Genomic DNA. Translation: AAP20955.1.
AY247667 Genomic DNA. Translation: AAP20956.1.
AY247668 Genomic DNA. Translation: AAP20957.1.
AY247669 Genomic DNA. Translation: AAP20958.1.
AY247670 Genomic DNA. Translation: AAP20959.1.
AY247671 Genomic DNA. Translation: AAP20960.1.
AY247672 Genomic DNA. Translation: AAP20961.1.
AY247673 Genomic DNA. Translation: AAP20962.1.
AY247674 Genomic DNA. Translation: AAP20963.1.
AY247675 Genomic DNA. Translation: AAP20964.1.
AY247676 Genomic DNA. Translation: AAP20965.1.
AY247677 Genomic DNA. Translation: AAP20966.1.
AY247678 Genomic DNA. Translation: AAP20967.1.
AY247679 Genomic DNA. Translation: AAP20968.1.
AY247680 Genomic DNA. Translation: AAP20969.1.
AY247681 Genomic DNA. Translation: AAP20970.1.
AY247682 Genomic DNA. Translation: AAP20971.1.
AY247683 Genomic DNA. Translation: AAP20972.1.
AY247684 Genomic DNA. Translation: AAP20973.1.
AY247685 Genomic DNA. Translation: AAP20974.1.
AY247686 Genomic DNA. Translation: AAP20975.1.
AY247687 Genomic DNA. Translation: AAP20976.1.
AY247688 Genomic DNA. Translation: AAP20977.1.
AY247689 Genomic DNA. Translation: AAP20978.1.
AY247690 Genomic DNA. Translation: AAP20979.1.
AY247691 Genomic DNA. Translation: AAP20980.1.
AY247692 Genomic DNA. Translation: AAP20981.1.
AY247693 Genomic DNA. Translation: AAP20982.1.
AY247694 Genomic DNA. Translation: AAP20983.1.
AY247695 Genomic DNA. Translation: AAP20984.1.
AY247696 Genomic DNA. Translation: AAP20985.1.
AY247697 Genomic DNA. Translation: AAP20986.1.
AY247698 Genomic DNA. Translation: AAP20987.1.
AY247699 Genomic DNA. Translation: AAP20988.1.
AY247700 Genomic DNA. Translation: AAP20989.1.
AY247701 Genomic DNA. Translation: AAP20990.1.
AY247702 Genomic DNA. Translation: AAP20991.1.
AY247703 Genomic DNA. Translation: AAP20992.1.
AY247704 Genomic DNA. Translation: AAP20993.1.
AY247705 Genomic DNA. Translation: AAP20994.1.
AY247706 Genomic DNA. Translation: AAP20995.1.
AY247707 Genomic DNA. Translation: AAP20996.1.
AY247708 Genomic DNA. Translation: AAP20997.1.
AY247709 Genomic DNA. Translation: AAP20998.1.
AY247710 Genomic DNA. Translation: AAP20999.1.
AY247711 Genomic DNA. Translation: AAP21000.1.
AY247712 Genomic DNA. Translation: AAP21001.1.
AY247713 Genomic DNA. Translation: AAP21002.1.
AE014296 Genomic DNA. Translation: AAF49946.1.
AY095091 mRNA. Translation: AAM11419.1. Sequence problems.
U57474 Genomic DNA. Translation: AAB46692.1.
U57475 Genomic DNA. Translation: AAB46693.1.
U57476 Genomic DNA. Translation: AAB46694.1.
U57477 Genomic DNA. Translation: AAB46695.1.
U57478 Genomic DNA. Translation: AAB46696.1.
U57479 Genomic DNA. Translation: AAB46697.1.
U57480 Genomic DNA. Translation: AAB46698.1.
U57481 Genomic DNA. Translation: AAB46699.1.
U57482 Genomic DNA. Translation: AAB46700.1.
U57483 Genomic DNA. Translation: AAB46701.1.
U57484 Genomic DNA. Translation: AAB46702.1.
U57485 Genomic DNA. Translation: AAB46703.1.
U57486 Genomic DNA. Translation: AAB46704.1.
U57487 Genomic DNA. Translation: AAB46705.1.
U57488 Genomic DNA. Translation: AAB46706.1.
PIRiA28022.
A34089.
A40122.
A41426.
B40122.
B41426.
C41426.
D41426.
E41426.
F41426.
G41426.
H41426.
I41426.
RefSeqiNP_001261749.1. NM_001274820.1.
NP_788500.1. NM_176322.3.
UniGeneiDm.2828.

3D structure databases

ProteinModelPortaliP08171.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi64746. 1 interactor.
DIPiDIP-21801N.
IntActiP08171. 1 interactor.
MINTiMINT-293517.
STRINGi7227.FBpp0305575.

Protein family/group databases

ESTHERidrome-este6. Carb_B_Arthropoda.
MEROPSiS09.947.

Proteomic databases

PaxDbiP08171.
PRIDEiP08171.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0076003; FBpp0075735; FBgn0000592.
FBtr0333383; FBpp0305575; FBgn0000592.
GeneIDi39392.
KEGGidme:Dmel_CG6917.

Organism-specific databases

CTDi39392.
FlyBaseiFBgn0000592. Est-6.

Phylogenomic databases

eggNOGiKOG1516. Eukaryota.
COG2272. LUCA.
GeneTreeiENSGT00680000100015.
InParanoidiP08171.
KOiK01044.
OMAiIVLSCLW.
OrthoDBiEOG091G046C.
PhylomeDBiP08171.

Miscellaneous databases

GenomeRNAii39392.
PROiP08171.

Gene expression databases

BgeeiFBgn0000592.
ExpressionAtlasiP08171. baseline.
GenevisibleiP08171. DM.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
[Graphical view]
PfamiPF00135. COesterase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEST6_DROME
AccessioniPrimary (citable) accession number: P08171
Secondary accession number(s): P91646
, P91647, P91648, P91649, P91650, P92173, P92195, P92200, Q867G7, Q867V2, Q867Y9, Q868B8, Q86CX4, Q86CX5, Q86CX6, Q86CX7, Q86CX8, Q86CX9, Q86CY0, Q86CY1, Q86CY2, Q86CY3, Q86CY4, Q86CY5, Q86CY6, Q86CY7, Q8SWT4, Q9U797, Q9U798, Q9U799, Q9U7A0, Q9V3U8, Q9XTN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: November 1, 1990
Last modified: November 30, 2016
This is version 155 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.