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P07979 (GUB_NICPL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lichenase

EC=3.2.1.73
Alternative name(s):
Endo-beta-1,3-1,4 glucanase
Gene names
Name:GN1
OrganismNicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)
Taxonomic identifier4092 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds.

Pathway

Glycan metabolism; beta-D-glucan degradation.

Miscellaneous

The expression of beta-glucanase is influenced by auxins and cytokinins.

Sequence similarities

Belongs to the glycosyl hydrolase 17 family.

Ontologies

Keywords
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionlicheninase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3030 Potential
Chain31 – 370340Lichenase
PRO_0000011898

Sites

Active site2711Nucleophile By similarity
Active site3281Proton donor By similarity

Experimental info

Sequence conflict1641S → T in AAA34078. Ref.2
Sequence conflict1991R → G in AAA34078. Ref.2
Sequence conflict2501S → L in AAA34078. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P07979 [UniParc].

Last modified November 1, 1997. Version 3.
Checksum: CB359DFD188F84C1

FASTA37040,599
        10         20         30         40         50         60 
MDTSHKHIAL QMAAIILLGL LVSSTEIVGA QSVGVCYGML GNNLPPASQV VQLYKSKNIR 

        70         80         90        100        110        120 
RMRLYDPNQA ALQALRGSNI EVMLGVPNSD LQNIAANPSN ANNWVQRNVR NFWPAVKFRY 

       130        140        150        160        170        180 
IAVGNEVSPV TGTSSLTRYL LPAMRNIRNA ISSAGLQNNI KVSSSVDMTL IGNSFPPSQG 

       190        200        210        220        230        240 
SFRNDVRSFI DPIIGFVRRI NSPLLVNIYP YFSYAGNPRD ISLPYALFTA PNVVVQDGSL 

       250        260        270        280        290        300 
GYRNLFDAMS DAVYAALSRA GGGSIEIVVS ESGWPSAGAF AATTNNAATY YKNLIQHVKR 

       310        320        330        340        350        360 
GSPRRPNKVI ETYLFAMFDE NNKNPELEKH FGLFSPNKQP KYPLSFGFSD RYWDISAENN 

       370 
ATAASLISEM 

« Hide

References

[1]"Primary structure of a hormonally regulated beta-glucanase of Nicotiana plumbaginifolia."
de Loose M., Alliotte T., Gheysen G., Genetello C., Gielen J., Soetaert P., van Montagu M., Inze D.
Gene 70:13-23(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. P2.
[2]"Tissue-specific and pathogen-induced regulation of a Nicotiana plumbaginifolia beta-1,3-glucanase gene."
Castresana C., de Carvalho F., Gheysen G., Habets M., Inze D., van Montagu M.
Plant Cell 2:1131-1143(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X07280 mRNA. Translation: CAA30261.1.
M63634 Genomic DNA. Translation: AAA34078.1.
PIRJQ0982.
S03209.

3D structure databases

ProteinModelPortalP07979.
SMRP07979. Positions 33-346.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH17. Glycoside Hydrolase Family 17.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00350.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR000490. Glyco_hydro_17.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00332. Glyco_hydro_17. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00587. GLYCOSYL_HYDROL_F17. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUB_NICPL
AccessionPrimary (citable) accession number: P07979
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: November 1, 1997
Last modified: February 19, 2014
This is version 80 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries