Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P07938

- SIG1S_REOVL

UniProt

P07938 - SIG1S_REOVL

Protein

Protein sigma-1-small

Gene

S1

Organism
Reovirus type 1 (strain Lang) (T1L) (Mammalian orthoreovirus 1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    GO - Biological processi

    1. suppression by virus of G2/M transition of host mitotic cell cycle Source: UniProtKB-KW

    Keywords - Biological processi

    Host G2/M cell cycle arrest by virus, Host-virus interaction, Modulation of host cell cycle by virus

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein sigma-1-small
    Short name:
    Sigma1s
    Alternative name(s):
    Sigma-s
    Sigma1NS
    Sigma1bNS
    p14
    Gene namesi
    Name:S1
    OrganismiReovirus type 1 (strain Lang) (T1L) (Mammalian orthoreovirus 1)
    Taxonomic identifieri10884 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesReoviridaeSpinareovirinaeOrthoreovirus
    Virus hostiMammalia [TaxID: 40674]
    ProteomesiUP000007253: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 119119Protein sigma-1-smallPRO_0000222757Add
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR003478. Capsid_sigma_1s.
    [Graphical view]
    PfamiPF02454. Sigma_1s. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P07938-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPSQKKSRK SRNKSRSTLM ISGLPILNST DLEDRLLTSA IASQPLSQDW    50
    VRWIIDLWVS RVRSRNYLTQ VARTLRAYPH WVTESMLSNH ELTVWIRSRL 100
    ISLDEHPLWR QMLEAYGQN 119
    Length:119
    Mass (Da):13,989
    Last modified:August 1, 1988 - v1
    Checksum:iD6EEE53353BC6190
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti71 – 711V → L in AAA47243. (PubMed:2430568)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M10260 Genomic RNA. Translation: AAA66878.1.
    M14779 Genomic RNA. Translation: AAA47277.1.
    M35963 Genomic RNA. Translation: AAA47243.1.
    PIRiB26436. MNXR1B.
    B34829.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M10260 Genomic RNA. Translation: AAA66878.1 .
    M14779 Genomic RNA. Translation: AAA47277.1 .
    M35963 Genomic RNA. Translation: AAA47243.1 .
    PIRi B26436. MNXR1B.
    B34829.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR003478. Capsid_sigma_1s.
    [Graphical view ]
    Pfami PF02454. Sigma_1s. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequences of the S1 genes of the three serotypes of reovirus."
      Cashdollar L.W., Chmelo R.A., Wiener J.R., Joklik W.K.
      Proc. Natl. Acad. Sci. U.S.A. 82:24-28(1985) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    2. "Biosynthesis of reovirus-specified polypeptides. Molecular cDNA cloning and nucleotide sequence of the reovirus serotype 1 Lang strain bicistronic s1 mRNA which encodes the minor capsid polypeptide sigma 1a and the nonstructural polypeptide sigma 1bNS."
      Munemitsu S.M., Atwater J.A., Samuel C.E.
      Biochem. Biophys. Res. Commun. 140:508-514(1986) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    3. "Structure of the reovirus cell-attachment protein: a model for the domain organization of sigma 1."
      Nibert M.L., Dermody T.S., Fields B.N.
      J. Virol. 64:2976-2989(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiSIG1S_REOVL
    AccessioniPrimary (citable) accession number: P07938
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1988
    Last sequence update: August 1, 1988
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3