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P07938

- SIG1S_REOVL

UniProt

P07938 - SIG1S_REOVL

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Protein

Protein sigma-1-small

Gene

S1

Organism
Reovirus type 1 (strain Lang) (T1L) (Mammalian orthoreovirus 1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Biological processi

  1. suppression by virus of G2/M transition of host mitotic cell cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Host G2/M cell cycle arrest by virus, Host-virus interaction, Modulation of host cell cycle by virus

Names & Taxonomyi

Protein namesi
Recommended name:
Protein sigma-1-small
Short name:
Sigma1s
Alternative name(s):
Sigma-s
Sigma1NS
Sigma1bNS
p14
Gene namesi
Name:S1
OrganismiReovirus type 1 (strain Lang) (T1L) (Mammalian orthoreovirus 1)
Taxonomic identifieri10884 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSpinareovirinaeOrthoreovirus
Virus hostiMammalia [TaxID: 40674]
ProteomesiUP000007253: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 119119Protein sigma-1-smallPRO_0000222757Add
BLAST

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR003478. Capsid_sigma_1s.
[Graphical view]
PfamiPF02454. Sigma_1s. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P07938-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPSQKKSRK SRNKSRSTLM ISGLPILNST DLEDRLLTSA IASQPLSQDW
60 70 80 90 100
VRWIIDLWVS RVRSRNYLTQ VARTLRAYPH WVTESMLSNH ELTVWIRSRL
110
ISLDEHPLWR QMLEAYGQN
Length:119
Mass (Da):13,989
Last modified:August 1, 1988 - v1
Checksum:iD6EEE53353BC6190
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti71 – 711V → L in AAA47243. (PubMed:2430568)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M10260 Genomic RNA. Translation: AAA66878.1.
M14779 Genomic RNA. Translation: AAA47277.1.
M35963 Genomic RNA. Translation: AAA47243.1.
PIRiB26436. MNXR1B.
B34829.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M10260 Genomic RNA. Translation: AAA66878.1 .
M14779 Genomic RNA. Translation: AAA47277.1 .
M35963 Genomic RNA. Translation: AAA47243.1 .
PIRi B26436. MNXR1B.
B34829.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR003478. Capsid_sigma_1s.
[Graphical view ]
Pfami PF02454. Sigma_1s. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequences of the S1 genes of the three serotypes of reovirus."
    Cashdollar L.W., Chmelo R.A., Wiener J.R., Joklik W.K.
    Proc. Natl. Acad. Sci. U.S.A. 82:24-28(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Biosynthesis of reovirus-specified polypeptides. Molecular cDNA cloning and nucleotide sequence of the reovirus serotype 1 Lang strain bicistronic s1 mRNA which encodes the minor capsid polypeptide sigma 1a and the nonstructural polypeptide sigma 1bNS."
    Munemitsu S.M., Atwater J.A., Samuel C.E.
    Biochem. Biophys. Res. Commun. 140:508-514(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  3. "Structure of the reovirus cell-attachment protein: a model for the domain organization of sigma 1."
    Nibert M.L., Dermody T.S., Fields B.N.
    J. Virol. 64:2976-2989(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiSIG1S_REOVL
AccessioniPrimary (citable) accession number: P07938
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: October 1, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3