Reviewed, UniProtKB/Swiss-Prot P07920 (ACCO2_SOLLC)

Names and origin

Protein names

Recommended name:
    1-aminocyclopropane-1-carboxylate oxidase 2
      Short name=ACC oxidase 2
    EC=1.14.17.4
Alternative name(s):
    Ethylene-forming enzyme
      Short name=EFE
    Protein GTOMA

Gene names

Name:

ACO2

Organism

Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

Taxonomic identifier

4081 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	1-aminocyclopropane-1-carboxylate + ascorbate + O2 = ethylene + cyanide + dehydroascorbate + CO2 + 2 H2O.
Cofactor	Iron.
Pathway	Alkene biosynthesis; ethylene biosynthesis via S-adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 2/2.
Tissue specificity	Leaves.
Induction	By wounding.
Sequence similarities	Belongs to the iron/ascorbate-dependent oxidoreductase family.

Ontologies

Keywords
Biological process	Ethylene biosynthesis Fruit ripening
Ligand	Iron Metal-binding Vitamin C
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	ethylene biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW ripening Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	1-aminocyclopropane-1-carboxylate oxidase activity Inferred from electronic annotation. Source: EC L-ascorbic acid binding Inferred from electronic annotation. Source: UniProtKB-KW iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 316	316	1-aminocyclopropane-1-carboxylate oxidase 2		PRO_0000067262
Sites
	Metal binding	177	1	Iron By similarity
	Metal binding	179	1	Iron By similarity
	Metal binding	234	1	Iron By similarity

Sequences

	Sequence		Length	Mass (Da)
	P07920-1 [UniParc]. Last modified August 1, 1988. Version 1. Checksum: 7701CFF1955AABC9	FASTA	316	36,168
	10 20 30 40 50 60 MENFPIINLE KLNGAERVAT MEKINDACEN WGFFELVNHG IPHEVMDTVE KLTKGHYKKC 70 80 90 100 110 120 MEQRFKELVA KKGLEGVEVE VTDMDWESTF FLRHLPSSNI SQLPDLDDVY REVMRDFRKR 130 140 150 160 170 180 LEKLAEELLD LLCENLGLEK SYLKNTFYGS KGPNFGTKVS NYPPCPKPDL IKGLRAHTDA 190 200 210 220 230 240 GGIILLFQDD KVSGLQLLKD GRWIDVPPMR HSIVVNLGDQ LEVITNGKYK SVMHRVIAQK 250 260 270 280 290 300 DGTRMSLASF YNPGNDALIY PAPALVDKEA EEHNKQVYPK FMFDDYMKLY ANLKFQAKEP 310 RFEAMKAMES DPIAIA

References

[1]	"Nucleotide sequence of an ethylene-related gene from tomato." Holdsworth M.J., Schuch W., Grierson D. Nucleic Acids Res. 15:10600-10600(1987) [PubMed: 3697103] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Ailsa Craig.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y00478 Genomic DNA. Translation: CAA68538.1.
PIR	S00519.
3D structure databases
HSSP	HSSP built from PDB template 1GP5 based on UniProtKB Q96323.
SMR	P07920. Positions 2-308.
ModBase	Search...
Family and domain databases
InterPro	IPR005123. Oxoglutarate/Fe-dep_Oase. [Graphical view]
Pfam	PF03171. 2OG-FeII_Oxy. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACCO2_SOLLC

Accession

Primary (citable) accession number: P07920

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1988
Last sequence update:	August 1, 1988
Last modified:	May 5, 2009
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)