Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P07804

- GLNA_ACIFR

UniProt

P07804 - GLNA_ACIFR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine synthetase

Gene

glnA

Organism
Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Enzyme regulationi

The activity of this enzyme is controlled by adenylation under conditions of abundant glutamine. The fully adenylated enzyme complex is inactive (By similarity).By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
  2. nitrogen fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
OrganismiAcidithiobacillus ferrooxidans (Thiobacillus ferrooxidans)
Taxonomic identifieri920 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 468468Glutamine synthetasePRO_0000153274Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei397 – 3971O-AMP-tyrosineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP07804.

Interactioni

Subunit structurei

Oligomer of 12 subunits arranged in the form of two hexagons.

Structurei

3D structure databases

ProteinModelPortaliP07804.
SMRiP07804. Positions 4-468.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Family and domain databases

Gene3Di3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR001637. Gln_synth_I_adenylation_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
TIGRFAMsiTIGR00653. GlnA. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00182. GLNA_ADENYLATION. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P07804-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGYSPSDVVK LIQEKDIKFI DFRFTDTKGK EQHVSVPGHV IEEDTFTEGK
60 70 80 90 100
AFDGSSIAGW KGINESDMIL LPDPDSAVLD PFMDETTLLL RCDVIEPATG
110 120 130 140 150
QGYERDPRSV AKRAEIYLKS TGIADTSFFG PEFFVFDSVT WNIDMSGCAY
160 170 180 190 200
KVDAEEAAWN SGKEYESGNM GHRLGVKGGY FPVPPVDSAQ DLRSAMCLAM
210 220 230 240 250
EEMGLKVEVH HHEVATAGQH EIGVGFNTLT PRRMRCKILK YVVHNVAAVR
260 270 280 290 300
QTATFMPKPV VGDNGSGMHV HQSLGKDGKN IFAGDLYGGL SEIALYYIGG
310 320 330 340 350
IIKHAKAVNA LTNPSTNSYK RLVPHFEAPV LLAYSAKNRS ASIRIPYVNS
360 370 380 390 400
PKARRIEVRF PDSTANPYLA FSAMLMAGLD GIQNKIHPAT AMDKNLYDLP
410 420 430 440 450
AEEQANIPGV AASLEEALRA LEADHDFLMK GGVFSESWLE GYLDVKWAEV
460
QTLRVTTHPV EFQMYYSL
Length:468
Mass (Da):51,614
Last modified:August 1, 1988 - v1
Checksum:i24710B272B3A7054
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M16626 Genomic DNA. Translation: AAA27370.1.
PIRiA29460. AJBCQF.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M16626 Genomic DNA. Translation: AAA27370.1 .
PIRi A29460. AJBCQF.

3D structure databases

ProteinModelPortali P07804.
SMRi P07804. Positions 4-468.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P07804.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR001637. Gln_synth_I_adenylation_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
TIGRFAMsi TIGR00653. GlnA. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00182. GLNA_ADENYLATION. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence of the glutamine synthetase gene and its controlling region from the acidophilic autotroph Thiobacillus ferrooxidans."
    Rawlings D.E., Jones W.A., O'Neill E.G., Woods D.R.
    Gene 53:211-217(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiGLNA_ACIFR
AccessioniPrimary (citable) accession number: P07804
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3