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Protein

Spore coat protein A

Gene

cotA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in brown pigmentation during sporogenesis.

GO - Molecular functioni

  • copper ion binding Source: GO_Central
  • hydroquinone:oxygen oxidoreductase activity Source: CACAO
  • oxidoreductase activity, oxidizing metal ions Source: GO_Central

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sporulation

Enzyme and pathway databases

BioCyciBSUB:BSU06300-MONOMER.
BRENDAi1.3.3.5. 658.
SABIO-RKP07788.

Names & Taxonomyi

Protein namesi
Recommended name:
Spore coat protein A
Gene namesi
Name:cotA
Synonyms:pig
Ordered Locus Names:BSU06300
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 513513Spore coat protein APRO_0000079257Add
BLAST

Proteomic databases

PaxDbiP07788.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100003538.

Structurei

Secondary structure

1
513
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi19 – 213Combined sources
Beta strandi26 – 3712Combined sources
Beta strandi46 – 516Combined sources
Beta strandi54 – 563Combined sources
Beta strandi59 – 635Combined sources
Beta strandi68 – 747Combined sources
Helixi86 – 883Combined sources
Beta strandi104 – 1074Combined sources
Helixi113 – 1153Combined sources
Helixi125 – 1273Combined sources
Beta strandi128 – 1303Combined sources
Beta strandi137 – 1415Combined sources
Beta strandi148 – 1547Combined sources
Turni157 – 1593Combined sources
Helixi160 – 1667Combined sources
Beta strandi169 – 1757Combined sources
Helixi177 – 1826Combined sources
Helixi187 – 1893Combined sources
Beta strandi190 – 20011Combined sources
Beta strandi210 – 2145Combined sources
Beta strandi231 – 2355Combined sources
Beta strandi238 – 2403Combined sources
Beta strandi242 – 2443Combined sources
Beta strandi247 – 25610Combined sources
Beta strandi263 – 2675Combined sources
Beta strandi273 – 2786Combined sources
Beta strandi281 – 29414Combined sources
Beta strandi299 – 3057Combined sources
Helixi307 – 3093Combined sources
Beta strandi313 – 3186Combined sources
Beta strandi322 – 3254Combined sources
Turni328 – 3325Combined sources
Beta strandi333 – 3386Combined sources
Helixi359 – 3613Combined sources
Beta strandi366 – 37813Combined sources
Beta strandi384 – 3885Combined sources
Beta strandi406 – 4138Combined sources
Beta strandi415 – 4173Combined sources
Beta strandi419 – 4257Combined sources
Beta strandi428 – 4369Combined sources
Helixi438 – 4447Combined sources
Beta strandi449 – 4513Combined sources
Helixi458 – 4603Combined sources
Beta strandi464 – 4696Combined sources
Beta strandi473 – 4808Combined sources
Beta strandi486 – 4938Combined sources
Helixi495 – 4984Combined sources
Turni499 – 5013Combined sources
Beta strandi503 – 5097Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1GSKX-ray1.70A1-513[»]
1OF0X-ray2.45A1-513[»]
1W6LX-ray2.00A1-513[»]
1W6WX-ray2.20A1-513[»]
1W8EX-ray2.20A1-513[»]
2BHFX-ray2.50A1-513[»]
2WSDX-ray1.60A1-513[»]
2X87X-ray2.00A1-513[»]
2X88X-ray1.80A1-513[»]
3ZDWX-ray2.45A1-513[»]
4A66X-ray1.95A1-513[»]
4A67X-ray2.10A1-513[»]
4A68X-ray2.00A1-513[»]
4AKOX-ray1.70A1-513[»]
4AKPX-ray2.00A1-513[»]
4AKQX-ray2.10A1-513[»]
4Q89X-ray2.31A/B1-513[»]
4Q8BX-ray1.91A/B1-513[»]
4YVNX-ray2.30A1-513[»]
4YVUX-ray2.30A1-513[»]
ProteinModelPortaliP07788.
SMRiP07788. Positions 2-511.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP07788.

Family & Domainsi

Sequence similaritiesi

To S.antibioticus phenoxazinone synthase (PhsA).Curated

Phylogenomic databases

eggNOGiENOG4107STQ. Bacteria.
COG2132. LUCA.
HOGENOMiHOG000096435.
InParanoidiP07788.
KOiK06324.
OMAiPYSGRYV.
PhylomeDBiP07788.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR008972. Cupredoxin.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 2 hits.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.

Sequencei

Sequence statusi: Complete.

P07788-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLEKFVDAL PIPDTLKPVQ QSKEKTYYEV TMEECTHQLH RDLPPTRLWG
60 70 80 90 100
YNGLFPGPTI EVKRNENVYV KWMNNLPSTH FLPIDHTIHH SDSQHEEPEV
110 120 130 140 150
KTVVHLHGGV TPDDSDGYPE AWFSKDFEQT GPYFKREVYH YPNQQRGAIL
160 170 180 190 200
WYHDHAMALT RLNVYAGLVG AYIIHDPKEK RLKLPSDEYD VPLLITDRTI
210 220 230 240 250
NEDGSLFYPS APENPSPSLP NPSIVPAFCG ETILVNGKVW PYLEVEPRKY
260 270 280 290 300
RFRVINASNT RTYNLSLDNG GDFIQIGSDG GLLPRSVKLN SFSLAPAERY
310 320 330 340 350
DIIIDFTAYE GESIILANSA GCGGDVNPET DANIMQFRVT KPLAQKDESR
360 370 380 390 400
KPKYLASYPS VQHERIQNIR TLKLAGTQDE YGRPVLLLNN KRWHDPVTET
410 420 430 440 450
PKVGTTEIWS IINPTRGTHP IHLHLVSFRV LDRRPFDIAR YQESGELSYT
460 470 480 490 500
GPAVPPPPSE KGWKDTIQAH AGEVLRIAAT FGPYSGRYVW HCHILEHEDY
510
DMMRPMDITD PHK
Length:513
Mass (Da):58,499
Last modified:May 30, 2000 - v4
Checksum:i836B83B458D75F87
GO

Sequence cautioni

The sequence BAA22774 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAA29165 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti347 – 36721DESRK…HERIQ → TKAESRSTSPHTLRYSMKDT in AAB62305 (PubMed:8969499).CuratedAdd
BLAST
Sequence conflicti414 – 4207PTRGTHP → RHAEHIL in AAB62305 (PubMed:8969499).Curated
Sequence conflicti451 – 4588GPAVPPPP → VRCPAAA in AAB62305 (PubMed:8969499).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51115 Genomic DNA. Translation: AAB62305.1.
AB007638 Genomic DNA. Translation: BAA22774.1. Different initiation.
AL009126 Genomic DNA. Translation: CAB12449.1.
X05678 Genomic DNA. Translation: CAA29165.1. Different initiation.
X07512 Genomic DNA. Translation: CAA30392.1.
U31756 Genomic DNA. Translation: AAC44642.1.
PIRiF69604.
RefSeqiNP_388511.1. NC_000964.3.
WP_003243170.1. NZ_JNCM01000032.1.

Genome annotation databases

EnsemblBacteriaiCAB12449; CAB12449; BSU06300.
GeneIDi936023.
KEGGibsu:BSU06300.
PATRICi18972900. VBIBacSub10457_0664.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51115 Genomic DNA. Translation: AAB62305.1.
AB007638 Genomic DNA. Translation: BAA22774.1. Different initiation.
AL009126 Genomic DNA. Translation: CAB12449.1.
X05678 Genomic DNA. Translation: CAA29165.1. Different initiation.
X07512 Genomic DNA. Translation: CAA30392.1.
U31756 Genomic DNA. Translation: AAC44642.1.
PIRiF69604.
RefSeqiNP_388511.1. NC_000964.3.
WP_003243170.1. NZ_JNCM01000032.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1GSKX-ray1.70A1-513[»]
1OF0X-ray2.45A1-513[»]
1W6LX-ray2.00A1-513[»]
1W6WX-ray2.20A1-513[»]
1W8EX-ray2.20A1-513[»]
2BHFX-ray2.50A1-513[»]
2WSDX-ray1.60A1-513[»]
2X87X-ray2.00A1-513[»]
2X88X-ray1.80A1-513[»]
3ZDWX-ray2.45A1-513[»]
4A66X-ray1.95A1-513[»]
4A67X-ray2.10A1-513[»]
4A68X-ray2.00A1-513[»]
4AKOX-ray1.70A1-513[»]
4AKPX-ray2.00A1-513[»]
4AKQX-ray2.10A1-513[»]
4Q89X-ray2.31A/B1-513[»]
4Q8BX-ray1.91A/B1-513[»]
4YVNX-ray2.30A1-513[»]
4YVUX-ray2.30A1-513[»]
ProteinModelPortaliP07788.
SMRiP07788. Positions 2-511.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100003538.

Proteomic databases

PaxDbiP07788.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12449; CAB12449; BSU06300.
GeneIDi936023.
KEGGibsu:BSU06300.
PATRICi18972900. VBIBacSub10457_0664.

Phylogenomic databases

eggNOGiENOG4107STQ. Bacteria.
COG2132. LUCA.
HOGENOMiHOG000096435.
InParanoidiP07788.
KOiK06324.
OMAiPYSGRYV.
PhylomeDBiP07788.

Enzyme and pathway databases

BioCyciBSUB:BSU06300-MONOMER.
BRENDAi1.3.3.5. 658.
SABIO-RKP07788.

Miscellaneous databases

EvolutionaryTraceiP07788.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR008972. Cupredoxin.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 2 hits.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiCOTA_BACSU
AccessioniPrimary (citable) accession number: P07788
Secondary accession number(s): O24818
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: May 30, 2000
Last modified: September 7, 2016
This is version 121 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.