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P07736 (RNU1_USTSP) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Guanyl-specific ribonuclease U1

Short name=RNase U1
EC=3.1.27.3
OrganismUstilago sphaerogena (Smut fungus)
Taxonomic identifier5271 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago

Protein attributes

Sequence length105 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.

Sequence similarities

Belongs to the ribonuclease N1/T1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 105105Guanyl-specific ribonuclease U1
PRO_0000137376

Sites

Active site371 By similarity
Active site571Proton acceptor By similarity
Active site921Proton donor By similarity

Amino acid modifications

Modified residue11Pyrrolidone carboxylic acid
Disulfide bond8 ↔ 103 Ref.1
Disulfide bond51 ↔ 87 Ref.1

Sequences

Sequence LengthMass (Da)Tools
P07736 [UniParc].

Last modified February 1, 1994. Version 2.
Checksum: 6AB6C3117A4B727A

FASTA10511,157
        10         20         30         40         50         60 
QGGVSVNCGG TYYSSTQVNR AINNAKSGQY SSTGYPHTYN NYEGFDFSDY CDGPYKEYPL 

        70         80         90        100 
KTSSSGYTGG SPGADRVVYD SNDGTFCGAI THTGASGNNF VQCSY 

« Hide

References

[1]"The amino acid sequence of ribonuclease U1, a guanine-specific ribonuclease from the fungus Ustilago sphaerogena."
Takahashi K., Hashimoto J.
J. Biochem. 103:313-320(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases

PIRA41445.

3D structure databases

ProteinModelPortalP07736.
SMRP07736. Positions 32-104.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.10.450.30. 1 hit.
InterProIPR000026. Gua-sp_ribonuclease_N1/T1.
IPR016191. Ribonuclease/ribotoxin.
[Graphical view]
PfamPF00545. Ribonuclease. 1 hit.
[Graphical view]
SUPFAMSSF53933. SSF53933. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNU1_USTSP
AccessionPrimary (citable) accession number: P07736
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: February 1, 1994
Last modified: April 16, 2014
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families