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P07732

- GTHB2_ONCTS

UniProt

P07732 - GTHB2_ONCTS

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Protein
Gonadotropin subunit beta-2
Gene
cgbb
Organism
Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in gametogenesis and steroidogenesis.

Keywords - Molecular functioni

Hormone

Names & Taxonomyi

Protein namesi
Recommended name:
Gonadotropin subunit beta-2
Alternative name(s):
GTH-II-beta
Gonadotropin beta-II chain
Gene namesi
Name:cgbb
OrganismiOncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)
Taxonomic identifieri74940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeOncorhynchus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323
Add
BLAST
Chaini24 – 142119Gonadotropin subunit beta-2
PRO_0000011703Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi29 ↔ 77 By similarity
Glycosylationi33 – 331N-linked (GlcNAc...) Inferred
Disulfide bondi43 ↔ 92 By similarity
Disulfide bondi46 ↔ 130 By similarity
Disulfide bondi54 ↔ 108 By similarity
Disulfide bondi58 ↔ 110 By similarity
Disulfide bondi113 ↔ 120 By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta chain.

Structurei

3D structure databases

ProteinModelPortaliP07732.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG006698.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiIPR029034. Cystine-knot_cytokine.
IPR006208. Glyco_hormone_CN.
IPR001545. Gonadotropin_bsu.
IPR018245. Gonadotropin_bsu_CS.
[Graphical view]
PANTHERiPTHR11515. PTHR11515. 1 hit.
PfamiPF00007. Cys_knot. 1 hit.
[Graphical view]
SMARTiSM00068. GHB. 1 hit.
[Graphical view]
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiPS00261. GLYCO_HORMONE_BETA_1. 1 hit.
PS00689. GLYCO_HORMONE_BETA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P07732-1 [UniParc]FASTAAdd to Basket

« Hide

MLGLHVGTLI SLFLCILLEP IEGSLMQPCQ PINQTVSLEK EGCPTCLVIR    50
APICSGHCVT KEPVFKSPFS TVYQHVCTYR DVRYEMIRLP DCPPWSDPHV 100
TYPVALSCDC SLCNMDTSDC TIESLQPDFC ITQRVLTDGD MW 142
Length:142
Mass (Da):15,903
Last modified:April 1, 1988 - v1
Checksum:iBEAEBEBFFD1292F8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X04404 mRNA. Translation: CAA27992.1.
PIRiA25800.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X04404 mRNA. Translation: CAA27992.1 .
PIRi A25800.

3D structure databases

ProteinModelPortali P07732.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG006698.

Family and domain databases

Gene3Di 2.10.90.10. 1 hit.
InterProi IPR029034. Cystine-knot_cytokine.
IPR006208. Glyco_hormone_CN.
IPR001545. Gonadotropin_bsu.
IPR018245. Gonadotropin_bsu_CS.
[Graphical view ]
PANTHERi PTHR11515. PTHR11515. 1 hit.
Pfami PF00007. Cys_knot. 1 hit.
[Graphical view ]
SMARTi SM00068. GHB. 1 hit.
[Graphical view ]
SUPFAMi SSF57501. SSF57501. 1 hit.
PROSITEi PS00261. GLYCO_HORMONE_BETA_1. 1 hit.
PS00689. GLYCO_HORMONE_BETA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning and sequencing of salmon gonadotropin beta subunit."
    Trinh K.-Y., Wang N.C., Hew C.-L., Crim L.W.
    Eur. J. Biochem. 159:619-624(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiGTHB2_ONCTS
AccessioniPrimary (citable) accession number: P07732
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: June 11, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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