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Protein

S-adenosyl-L-methionine hydrolase

Gene
N/A
Organism
Enterobacteria phage T3 (Bacteriophage T3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cleaves of S-adenosylmethionine and may therefore prevent both modification and degradation of viral DNA by the host restriction-modification complex.1 Publication

Catalytic activityi

S-adenosyl-L-methionine + H2O = L-homoserine + methylthioadenosine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processHost-virus interaction, Restriction-modification system evasion by virus
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
S-adenosyl-L-methionine hydrolase (EC:3.3.1.2)
Short name:
ADOMetase
Short name:
Adenosylmethionine hydrolase
Short name:
SAMase
OrganismiEnterobacteria phage T3 (Bacteriophage T3)
Taxonomic identifieri10759 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000002092 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001065481 – 152S-adenosyl-L-methionine hydrolaseAdd BLAST152

Structurei

3D structure databases

SMRiP07693.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiView protein in InterPro
IPR016290. S-AdoMet_hydrolase.
PIRSFiPIRSF001110. SAM_hydrolase. 1 hit.

Sequencei

Sequence statusi: Complete.

P07693-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIFTKEPAHV FYVLVSAFRS NLCDEVNMSR HRHMVSTLRA APGLYGSVES
60 70 80 90 100
TDLTGCYREA ISSAPTEEKT VRVRCKDKAQ ALNVARLACN EWEQDCVLVY
110 120 130 140 150
KSQTHTAGLV YAKGIDGYKA ERLPGSFQEV PKGAPLQGCF TIDEFGRRWQ

VQ
Length:152
Mass (Da):17,035
Last modified:April 1, 1988 - v1
Checksum:i0B28B872A91DD63C
GO

Sequence cautioni

The sequence CAA28478 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti9H → N in AGM10703 (Ref. 3) Curated1
Sequence conflicti9H → N in CAC86259 (PubMed:12079351).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04791 Genomic DNA. Translation: CAA28477.1.
X04791 Genomic DNA. Translation: CAA28478.1. Different initiation.
AJ318471 Genomic DNA. Translation: CAC86259.1.
KC960671 Genomic DNA. Translation: AGM10703.1.
PIRiA26441. DABPT3.
RefSeqiNP_523296.1. NC_003298.1.
NP_523297.1. NC_003298.1.

Genome annotation databases

GeneIDi927434.
927435.
KEGGivg:927434.
vg:927435.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiADOM_BPT3
AccessioniPrimary (citable) accession number: P07693
Secondary accession number(s): Q8W5V0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: May 10, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome