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Protein

Transcriptional repressor protein KorB

Gene

korB

Organism
Escherichia coli
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

In conjunction with KorA, inhibits the transcription of the kilA, trfA and korAB operons. Is also involved in the negative control of the kilB operon.

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • protein homodimerization activity Source: CAFA

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor protein KorB
Gene namesi
Name:korB
Encoded oniPlasmid IncP-alpha RK20 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

GO - Cellular componenti

  • protein-containing complex Source: CAFA

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001786991 – 358Transcriptional repressor protein KorBAdd BLAST358

Proteomic databases

PRIDEiP07674

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
trfBP030522EBI-6405482,EBI-6405477

GO - Molecular functioni

  • protein homodimerization activity Source: CAFA

Protein-protein interaction databases

DIPiDIP-17007N
IntActiP07674, 1 interactor

Structurei

Secondary structure

1358
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi141 – 148Combined sources8
Helixi154 – 166Combined sources13
Helixi171 – 178Combined sources8
Helixi182 – 189Combined sources8
Helixi190 – 192Combined sources3
Helixi196 – 203Combined sources8
Helixi210 – 222Combined sources13
Helixi224 – 232Combined sources9
Helixi240 – 251Combined sources12
Beta strandi308 – 313Combined sources6
Beta strandi316 – 320Combined sources5
Beta strandi331 – 336Combined sources6
Turni337 – 339Combined sources3
Beta strandi342 – 346Combined sources5
Helixi347 – 349Combined sources3
Beta strandi351 – 356Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IGQX-ray1.70A/B/C/D297-358[»]
1IGUX-ray2.20A/B297-358[»]
1R71X-ray2.20A/B/C/D117-294[»]
DisProtiDP00656
ProteinModelPortaliP07674
SMRiP07674
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP07674

Family & Domainsi

Sequence similaritiesi

Belongs to the ParB family.Curated

Family and domain databases

Gene3Di2.30.30.150, 1 hit
InterProiView protein in InterPro
IPR010575 KorB_C
IPR037048 KorB_C_sf
IPR013741 KorB_domain
IPR004437 ParB/RepB/Spo0J
IPR003115 ParB/Sulfiredoxin_dom
IPR036086 ParB/Sulfiredoxin_sf
IPR008988 Transcriptional_repressor_C
PfamiView protein in Pfam
PF08535 KorB, 1 hit
PF06613 KorB_C, 1 hit
PF02195 ParBc, 1 hit
SMARTiView protein in SMART
SM00470 ParB, 1 hit
SUPFAMiSSF110849 SSF110849, 1 hit
SSF50037 SSF50037, 1 hit
TIGRFAMsiTIGR00180 parB_part, 1 hit

Sequencei

Sequence statusi: Complete.

P07674-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAAQAKTTK KNTAAAAQEA AGAAQPSGLG LDSIGDLSSL LDAPAASQGG
60 70 80 90 100
SGPIELDLDL IDEDPHQPRT ADNPGFSPES IAEIGATIKE RGVKSPISVR
110 120 130 140 150
ENQEQPGRYI INHGARRYRG SKWAGKKSIP AFIDNDYNEA DQVIENLQRN
160 170 180 190 200
ELTPREIADF IGRELAKGKK KGDIAKEIGK SPAFITQHVT LLDLPEKIAD
210 220 230 240 250
AFNTGRVRDV TVVNELVTAF KKRPEEVEAW LDDDTQEITR GTVKLLREFL
260 270 280 290 300
DEKGRDPNTV DAFNGQTDAE RDAEAGDGQD GEDGDQDGKD AKEKGAKEPD
310 320 330 340 350
PDKLKKAIVQ VEHDERPARL ILNRRPPAEG YAWLKYEDDG QEFEANLADV

KLVALIEG
Length:358
Mass (Da):39,011
Last modified:April 1, 1988 - v1
Checksum:i52F49477363F2279
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y00448 Genomic DNA Translation: CAA68503.1
X03962 Genomic DNA Translation: CAA27598.1
X06543 Genomic DNA Translation: CAA29790.1
PIRiA26837 RPECKB
RefSeqiWP_011205828.1, NZ_NJTR01000055.1

Similar proteinsi

Entry informationi

Entry nameiKORB2_ECOLX
AccessioniPrimary (citable) accession number: P07674
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Plasmid

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