Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serendipity locus protein beta

Gene

Sry-beta

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Binds to the consensus DNA sequence 5'-YCAGAGATGCGCA-3'.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri171 – 19323C2H2-type 1; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri201 – 22323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri229 – 25123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri257 – 27923C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri286 – 30823C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri315 – 33723C2H2-type 6PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Serendipity locus protein beta
Gene namesi
Name:Sry-beta
Synonyms:Sry-b
ORF Names:CG7938
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0003511. Sry-beta.

Subcellular locationi

  • Nucleus 1 Publication

GO - Cellular componenti

  • nucleus Source: UniProtKB
  • polytene chromosome interband Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 356356Serendipity locus protein betaPRO_0000047049Add
BLAST

Proteomic databases

PaxDbiP07665.

Expressioni

Developmental stagei

Expressed both maternally and zygotically. Abundant in early embryos and present in very low amounts at every stage of the life-cycle.2 Publications

Gene expression databases

BgeeiFBgn0003511.
GenevisibleiP07665. DM.

Interactioni

Subunit structurei

Binds chromatin; requires N-terminal regions to form protein-protein contacts, in addition to DNA specific recognition by the zinc fingers.

Protein-protein interaction databases

BioGridi68426. 6 interactions.
IntActiP07665. 4 interactions.
MINTiMINT-303581.
STRINGi7227.FBpp0084922.

Structurei

3D structure databases

ProteinModelPortaliP07665.
SMRiP07665. Positions 166-343.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 6 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri171 – 19323C2H2-type 1; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri201 – 22323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri229 – 25123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri257 – 27923C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri286 – 30823C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri315 – 33723C2H2-type 6PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000130160.
InParanoidiP07665.
OMAiECEEFMK.
OrthoDBiEOG091G0CLO.
PhylomeDBiP07665.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P07665-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSTRPFCFV CGKEKSVGVF QLIEGCIVPG TFKPIKDILK YFEKIINQRL
60 70 80 90 100
ELLPNSAACR DCLEYLFNYD RLVRNLSQVQ RQIADALLGC RQVEGKAETK
110 120 130 140 150
QQAAKRARVQ VPAFKIVQAT ALKEPERQPG EEDECEEFMK EEMLDEEFQF
160 170 180 190 200
SEPDDSMPSS EEEFFTETTE IPCHICGEMF SSQEVLERHI KADTCQKSEQ
210 220 230 240 250
ATCNVCGLKV KDDEVLDLHM NLHEGKTELE CRYCDKKFSH KRNVLRHMEV
260 270 280 290 300
HWDKKKYQCD KCGERFSLSW LMYNHLMRHD AEENALICEV CHQQFKTKRT
310 320 330 340 350
YKHHLRTHQT DRPRYPCPDC EKSFVDKYTL KVHKRVHQPV EKPESAEAKE

ATVTFF
Length:356
Mass (Da):41,709
Last modified:August 16, 2005 - v2
Checksum:i6B5F2206A20CE8D4
GO

Sequence cautioni

The sequence CAA26896 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03121 Genomic DNA. Translation: CAA26896.1. Sequence problems.
AE014297 Genomic DNA. Translation: AAF56998.1.
AY118322 mRNA. Translation: AAM48351.1.
PIRiA23351.
RefSeqiNP_001303451.1. NM_001316522.1.
NP_524579.1. NM_079840.3.
UniGeneiDm.1378.

Genome annotation databases

EnsemblMetazoaiFBtr0085556; FBpp0084922; FBgn0003511.
FBtr0346861; FBpp0312401; FBgn0003511.
GeneIDi43570.
KEGGidme:Dmel_CG7938.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03121 Genomic DNA. Translation: CAA26896.1. Sequence problems.
AE014297 Genomic DNA. Translation: AAF56998.1.
AY118322 mRNA. Translation: AAM48351.1.
PIRiA23351.
RefSeqiNP_001303451.1. NM_001316522.1.
NP_524579.1. NM_079840.3.
UniGeneiDm.1378.

3D structure databases

ProteinModelPortaliP07665.
SMRiP07665. Positions 166-343.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi68426. 6 interactions.
IntActiP07665. 4 interactions.
MINTiMINT-303581.
STRINGi7227.FBpp0084922.

Proteomic databases

PaxDbiP07665.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0085556; FBpp0084922; FBgn0003511.
FBtr0346861; FBpp0312401; FBgn0003511.
GeneIDi43570.
KEGGidme:Dmel_CG7938.

Organism-specific databases

CTDi43570.
FlyBaseiFBgn0003511. Sry-beta.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000130160.
InParanoidiP07665.
OMAiECEEFMK.
OrthoDBiEOG091G0CLO.
PhylomeDBiP07665.

Miscellaneous databases

GenomeRNAii43570.
PROiP07665.

Gene expression databases

BgeeiFBgn0003511.
GenevisibleiP07665. DM.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSRYB_DROME
AccessioniPrimary (citable) accession number: P07665
Secondary accession number(s): Q9VAB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: August 16, 2005
Last modified: September 7, 2016
This is version 149 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.