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P07659

- RPOL_BPT3

UniProt

P07659 - RPOL_BPT3

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Protein
DNA-directed RNA polymerase
Gene
1
Organism
Enterobacteria phage T3 (Bacteriophage T3)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei538 – 5381 By similarity
Active sitei632 – 6321 By similarity
Active sitei813 – 8131 By similarity

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase (EC:2.7.7.6)
Gene namesi
Name:1
OrganismiEnterobacteria phage T3 (Bacteriophage T3)
Taxonomic identifieri10759 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7likevirus
Virus hostiEscherichia coli [TaxID: 562]

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 884884DNA-directed RNA polymerase
PRO_0000087748Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP07659.
SMRiP07659. Positions 6-884.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.1320.10. 1 hit.
1.10.287.260. 1 hit.
InterProiIPR024075. DNA-dir_RNA_pol_helix_hairpin.
IPR002092. DNA-dir_Rpol_phage-type.
IPR029262. RPOL_N.
[Graphical view]
PANTHERiPTHR10102. PTHR10102. 1 hit.
PfamiPF00940. RNA_pol. 1 hit.
PF14700. RPOL_N. 1 hit.
[Graphical view]
PROSITEiPS00900. RNA_POL_PHAGE_1. 1 hit.
PS00489. RNA_POL_PHAGE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P07659-1 [UniParc]FASTAAdd to Basket

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MNIIENIEKN DFSEIELAAI PFNTLADHYG SALAKEQLAL EHESYELGER    50
RFLKMLERQA KAGEIADNAA AKPLLATLLP KLTTRIVEWL EEYASKKGRK 100
PSAYAPLQLL KPEASAFITL KVILASLTST NMTTIQAAAG MLGKAIEDEA 150
RFGRIRDLEA KHFKKHVEEQ LNKRHGQVYK KAFMQVVEAD MIGRGLLGGE 200
AWSSWDKETT MHVGIRLIEM LIESTGLVEL QRHNAGNAGS DHEALQLAQE 250
YVDVLAKRAG ALAGISPMFQ PCVVPPKPWV AITGGGYWAN GRRPLALVRT 300
HSKKGLMRYE DVYMPEVYKA VNLAQNTAWK INKKVLAVVN EIVNWKNCPV 350
ADIPSLERQE LPPKPDDIDT NEAALKEWKK AAAGIYRLDK ARVSRRISLE 400
FMLEQANKFA SKKAIWFPYN MDWRGRVYAV PMFNPQGNDM TKGLLTLAKG 450
KPIGEEGFYW LKIHGANCAG VDKVPFPERI AFIEKHVDDI LACAKDPINN 500
TWWAEQDSPF CFLAFCFEYA GVTHHGLSYN CSLPLAFDGS CSGIQHFSAM 550
LRDEVGGRAV NLLPSETVQD IYGIVAQKVN EILKQDAING TPNEMITVTD 600
KDTGEISEKL KLGTSTLAQQ WLAYGVTRSV TKRSVMTLAY GSKEFGFRQQ 650
VLDDTIQPAI DSGKGLMFTQ PNQAAGYMAK LIWDAVSVTV VAAVEAMNWL 700
KSAAKLLAAE VKDKKTKEIL RHRCAVHWTT PDGFPVWQEY RKPLQKRLDM 750
IFLGQFRLQP TINTLKDSGI DAHKQESGIA PNFVHSQDGS HLRMTVVYAH 800
EKYGIESFAL IHDSFGTIPA DAGKLFKAVR ETMVITYENN DVLADFYSQF 850
ADQLHETQLD KMPPLPKKGN LNLQDILKSD FAFA 884
Length:884
Mass (Da):98,790
Last modified:April 1, 1988 - v1
Checksum:iD589E02D879ADA45
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X05031 Genomic DNA. Translation: CAA28696.1.
X17255 Genomic DNA. Translation: CAA35121.1.
X02981 Genomic DNA. Translation: CAA26719.1.
PIRiA29060. RNBPT3.
RefSeqiNP_523301.1. NC_003298.1.

Genome annotation databases

GeneIDi927437.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X05031 Genomic DNA. Translation: CAA28696.1 .
X17255 Genomic DNA. Translation: CAA35121.1 .
X02981 Genomic DNA. Translation: CAA26719.1 .
PIRi A29060. RNBPT3.
RefSeqi NP_523301.1. NC_003298.1.

3D structure databases

ProteinModelPortali P07659.
SMRi P07659. Positions 6-884.
ModBasei Search...

Chemistry

ChEMBLi CHEMBL4854.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 927437.

Family and domain databases

Gene3Di 1.10.1320.10. 1 hit.
1.10.287.260. 1 hit.
InterProi IPR024075. DNA-dir_RNA_pol_helix_hairpin.
IPR002092. DNA-dir_Rpol_phage-type.
IPR029262. RPOL_N.
[Graphical view ]
PANTHERi PTHR10102. PTHR10102. 1 hit.
Pfami PF00940. RNA_pol. 1 hit.
PF14700. RPOL_N. 1 hit.
[Graphical view ]
PROSITEi PS00900. RNA_POL_PHAGE_1. 1 hit.
PS00489. RNA_POL_PHAGE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Hausmann.
  2. "Sequence of a conditionally essential region of bacteriophage T3, including the primary origin of DNA replication."
    Schmitt M.P., Beck P.J., Kearney C.A., Spence J.L., Digiovanni D., Condreay J.P., Molineux I.J.
    J. Mol. Biol. 193:479-495(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 855-884.
    Strain: Luria.

Entry informationi

Entry nameiRPOL_BPT3
AccessioniPrimary (citable) accession number: P07659
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: June 11, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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