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Protein

Phosphate transport system permease protein PstA

Gene

pstA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki
  • phosphate ion transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:PSTA-MONOMER.
ECOL316407:JW3704-MONOMER.
MetaCyc:PSTA-MONOMER.

Protein family/group databases

TCDBi3.A.1.7.1. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate transport system permease protein PstA
Gene namesi
Name:pstA
Synonyms:phoT
Ordered Locus Names:b3726, JW3704
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10782. pstA.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 28CytoplasmicSequence analysisAdd BLAST28
Transmembranei29 – 50HelicalPROSITE-ProRule annotationAdd BLAST22
Topological domaini51 – 82PeriplasmicSequence analysisAdd BLAST32
Transmembranei83 – 102HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini103 – 126CytoplasmicSequence analysisAdd BLAST24
Transmembranei127 – 146HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini147 – 150PeriplasmicSequence analysis4
Transmembranei151 – 169HelicalPROSITE-ProRule annotationAdd BLAST19
Topological domaini170 – 204CytoplasmicSequence analysisAdd BLAST35
Transmembranei205 – 223HelicalPROSITE-ProRule annotationAdd BLAST19
Topological domaini224 – 266PeriplasmicSequence analysisAdd BLAST43
Transmembranei267 – 286HelicalPROSITE-ProRule annotationAdd BLAST20
Topological domaini287 – 296CytoplasmicSequence analysis10

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoliWiki
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000601931 – 296Phosphate transport system permease protein PstAAdd BLAST296

Proteomic databases

PaxDbiP07654.
PRIDEiP07654.

Interactioni

Protein-protein interaction databases

BioGridi4262142. 12 interactors.
STRINGi511145.b3726.

Structurei

3D structure databases

ProteinModelPortaliP07654.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini83 – 286ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST204

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E2Z. Bacteria.
COG0581. LUCA.
HOGENOMiHOG000074142.
InParanoidiP07654.
KOiK02038.
OMAiAKMGHFS.
PhylomeDBiP07654.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR005672. Phosphate_PstA.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR00974. 3a0107s02c. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P07654-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMVEMQTTA ALAESRRKMQ ARRRLKNRIA LTLSMATMAF GLFWLIWILM
60 70 80 90 100
STITRGIDGM SLALFTEMTP PPNTEGGGLA NALAGSGLLI LWATVFGTPL
110 120 130 140 150
GIMAGIYLAE YGRKSWLAEV IRFINDILLS APSIVVGLFV YTIVVAQMEH
160 170 180 190 200
FSGWAGVIAL ALLQVPIVIR TTENMLKLVP YSLREAAYAL GTPKWKMISA
210 220 230 240 250
ITLKASVSGI MTGILLAIAR IAGETAPLLF TALSNQFWST DMMQPIANLP
260 270 280 290
VTIFKFAMSP FAEWQQLAWA GVLIITLCVL LLNILARVVF AKNKHG
Length:296
Mass (Da):32,322
Last modified:April 1, 1988 - v1
Checksum:iBFEADEC0B9851DC7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02723 Genomic DNA. Translation: CAA26508.1.
K01992 Genomic DNA. Translation: AAA24380.1.
L10328 Genomic DNA. Translation: AAA62077.1.
U00096 Genomic DNA. Translation: AAC76749.1.
AP009048 Genomic DNA. Translation: BAE77562.1.
PIRiB23311. BVECPT.
RefSeqiNP_418182.1. NC_000913.3.
WP_001251998.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76749; AAC76749; b3726.
BAE77562; BAE77562; BAE77562.
GeneIDi948239.
KEGGiecj:JW3704.
eco:b3726.
PATRICi32122949. VBIEscCol129921_3850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02723 Genomic DNA. Translation: CAA26508.1.
K01992 Genomic DNA. Translation: AAA24380.1.
L10328 Genomic DNA. Translation: AAA62077.1.
U00096 Genomic DNA. Translation: AAC76749.1.
AP009048 Genomic DNA. Translation: BAE77562.1.
PIRiB23311. BVECPT.
RefSeqiNP_418182.1. NC_000913.3.
WP_001251998.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP07654.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262142. 12 interactors.
STRINGi511145.b3726.

Protein family/group databases

TCDBi3.A.1.7.1. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP07654.
PRIDEiP07654.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76749; AAC76749; b3726.
BAE77562; BAE77562; BAE77562.
GeneIDi948239.
KEGGiecj:JW3704.
eco:b3726.
PATRICi32122949. VBIEscCol129921_3850.

Organism-specific databases

EchoBASEiEB0775.
EcoGeneiEG10782. pstA.

Phylogenomic databases

eggNOGiENOG4105E2Z. Bacteria.
COG0581. LUCA.
HOGENOMiHOG000074142.
InParanoidiP07654.
KOiK02038.
OMAiAKMGHFS.
PhylomeDBiP07654.

Enzyme and pathway databases

BioCyciEcoCyc:PSTA-MONOMER.
ECOL316407:JW3704-MONOMER.
MetaCyc:PSTA-MONOMER.

Miscellaneous databases

PROiP07654.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR005672. Phosphate_PstA.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR00974. 3a0107s02c. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPSTA_ECOLI
AccessioniPrimary (citable) accession number: P07654
Secondary accession number(s): Q2M844
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: November 30, 2016
This is version 136 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.