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Protein

Plasmid partition protein A

Gene

parA

Organism
Escherichia coli
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

This protein is essential for plasmid partition. It ensures the proper distribution of newly replicated plasmids to daughter cells during cell division. ParA is trans-acting.

GO - Molecular functioni

  • identical protein binding Source: IntAct

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Plasmid partition

Names & Taxonomyi

Protein namesi
Recommended name:
Plasmid partition protein A
Gene namesi
Name:parA
Encoded oniPlasmid P10 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000684041 – 398Plasmid partition protein AAdd BLAST398

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-7011519,EBI-7011519

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

IntActiP07620. 1 interactor.
MINTiMINT-7290704.

Structurei

Secondary structure

1398
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 25Combined sources20
Turni26 – 28Combined sources3
Helixi43 – 48Combined sources6
Helixi54 – 67Combined sources14
Beta strandi73 – 75Combined sources3
Beta strandi77 – 82Combined sources6
Helixi86 – 95Combined sources10
Helixi101 – 103Combined sources3
Beta strandi109 – 113Combined sources5
Beta strandi116 – 121Combined sources6
Helixi122 – 135Combined sources14
Turni137 – 139Combined sources3
Helixi140 – 142Combined sources3
Beta strandi146 – 151Combined sources6
Helixi156 – 161Combined sources6
Helixi164 – 167Combined sources4
Helixi174 – 180Combined sources7
Helixi184 – 190Combined sources7
Beta strandi200 – 203Combined sources4
Helixi209 – 214Combined sources6
Helixi216 – 223Combined sources8
Turni229 – 231Combined sources3
Helixi232 – 236Combined sources5
Helixi238 – 241Combined sources4
Turni242 – 244Combined sources3
Beta strandi246 – 252Combined sources7
Beta strandi254 – 256Combined sources3
Helixi258 – 266Combined sources9
Beta strandi268 – 274Combined sources7
Helixi278 – 300Combined sources23
Beta strandi310 – 317Combined sources8
Helixi321 – 334Combined sources14
Helixi335 – 337Combined sources3
Helixi347 – 354Combined sources8
Turni359 – 361Combined sources3
Turni364 – 366Combined sources3
Helixi371 – 397Combined sources27

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EZ2X-ray2.05A/B1-398[»]
3EZ6X-ray2.58A/B1-398[»]
3EZ7X-ray2.92A1-398[»]
ProteinModelPortaliP07620.
SMRiP07620.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP07620.

Family & Domainsi

Sequence similaritiesi

Belongs to the ParA family.Curated

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR025669. AAA_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13614. AAA_31. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

P07620-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSSQLHKV AQRANRMLNV LTEQVQLQKD ELHANEFYQV YAKAALAKLP
60 70 80 90 100
LLTRANVDYA VSEMEEKGYV FDKRPAGSSM KYAMSIQNII DIYEHRGVPK
110 120 130 140 150
YRDRYSEAYV IFISNLKGGV SKTVSTVSLA HAMRAHPHLL MEDLRILVID
160 170 180 190 200
LDPQSSATMF LSHKHSIGIV NATSAQAMLQ NVSREELLEE FIVPSVVPGV
210 220 230 240 250
DVMPASIDDA FIASDWRELC NEHLPGQNIH AVLKENVIDK LKSDYDFILV
260 270 280 290 300
DSGPHLDAFL KNALASANIL FTPLPPATVD FHSSLKYVAR LPELVKLISD
310 320 330 340 350
EGCECQLATN IGFMSKLSNK ADHKYCHSLA KEVFGGDMLD VFLPRLDGFE
360 370 380 390
RCGESFDTVI SANPATYVGS ADALKNARIA AEDFAKAVFD RIEFIRSN
Length:398
Mass (Da):44,270
Last modified:April 1, 1988 - v1
Checksum:i9CB45EB82B8ADBCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02380 Genomic DNA. Translation: AAA99230.1.
X02954 Genomic DNA. Translation: CAA26698.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02380 Genomic DNA. Translation: AAA99230.1.
X02954 Genomic DNA. Translation: CAA26698.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EZ2X-ray2.05A/B1-398[»]
3EZ6X-ray2.58A/B1-398[»]
3EZ7X-ray2.92A1-398[»]
ProteinModelPortaliP07620.
SMRiP07620.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP07620. 1 interactor.
MINTiMINT-7290704.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP07620.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR025669. AAA_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13614. AAA_31. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPARA_ECOLX
AccessioniPrimary (citable) accession number: P07620
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Plasmid

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.