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Protein

Plasmid partition protein A

Gene

parA

Organism
Escherichia coli
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

This protein is essential for plasmid partition. It ensures the proper distribution of newly replicated plasmids to daughter cells during cell division. ParA is trans-acting.

GO - Molecular functioni

  • identical protein binding Source: IntAct

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Plasmid partition

Names & Taxonomyi

Protein namesi
Recommended name:
Plasmid partition protein A
Gene namesi
Name:parA
Encoded oniPlasmid P10 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398Plasmid partition protein APRO_0000068404Add
BLAST

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-7011519,EBI-7011519

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

IntActiP07620. 1 interaction.
MINTiMINT-7290704.

Structurei

Secondary structure

1
398
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 2520Combined sources
Turni26 – 283Combined sources
Helixi43 – 486Combined sources
Helixi54 – 6714Combined sources
Beta strandi73 – 753Combined sources
Beta strandi77 – 826Combined sources
Helixi86 – 9510Combined sources
Helixi101 – 1033Combined sources
Beta strandi109 – 1135Combined sources
Beta strandi116 – 1216Combined sources
Helixi122 – 13514Combined sources
Turni137 – 1393Combined sources
Helixi140 – 1423Combined sources
Beta strandi146 – 1516Combined sources
Helixi156 – 1616Combined sources
Helixi164 – 1674Combined sources
Helixi174 – 1807Combined sources
Helixi184 – 1907Combined sources
Beta strandi200 – 2034Combined sources
Helixi209 – 2146Combined sources
Helixi216 – 2238Combined sources
Turni229 – 2313Combined sources
Helixi232 – 2365Combined sources
Helixi238 – 2414Combined sources
Turni242 – 2443Combined sources
Beta strandi246 – 2527Combined sources
Beta strandi254 – 2563Combined sources
Helixi258 – 2669Combined sources
Beta strandi268 – 2747Combined sources
Helixi278 – 30023Combined sources
Beta strandi310 – 3178Combined sources
Helixi321 – 33414Combined sources
Helixi335 – 3373Combined sources
Helixi347 – 3548Combined sources
Turni359 – 3613Combined sources
Turni364 – 3663Combined sources
Helixi371 – 39727Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3EZ2X-ray2.05A/B1-398[»]
3EZ6X-ray2.58A/B1-398[»]
3EZ7X-ray2.92A1-398[»]
ProteinModelPortaliP07620.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP07620.

Family & Domainsi

Sequence similaritiesi

Belongs to the ParA family.Curated

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR025669. AAA_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13614. AAA_31. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

P07620-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSSQLHKV AQRANRMLNV LTEQVQLQKD ELHANEFYQV YAKAALAKLP
60 70 80 90 100
LLTRANVDYA VSEMEEKGYV FDKRPAGSSM KYAMSIQNII DIYEHRGVPK
110 120 130 140 150
YRDRYSEAYV IFISNLKGGV SKTVSTVSLA HAMRAHPHLL MEDLRILVID
160 170 180 190 200
LDPQSSATMF LSHKHSIGIV NATSAQAMLQ NVSREELLEE FIVPSVVPGV
210 220 230 240 250
DVMPASIDDA FIASDWRELC NEHLPGQNIH AVLKENVIDK LKSDYDFILV
260 270 280 290 300
DSGPHLDAFL KNALASANIL FTPLPPATVD FHSSLKYVAR LPELVKLISD
310 320 330 340 350
EGCECQLATN IGFMSKLSNK ADHKYCHSLA KEVFGGDMLD VFLPRLDGFE
360 370 380 390
RCGESFDTVI SANPATYVGS ADALKNARIA AEDFAKAVFD RIEFIRSN
Length:398
Mass (Da):44,270
Last modified:April 1, 1988 - v1
Checksum:i9CB45EB82B8ADBCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02380 Genomic DNA. Translation: AAA99230.1.
X02954 Genomic DNA. Translation: CAA26698.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02380 Genomic DNA. Translation: AAA99230.1.
X02954 Genomic DNA. Translation: CAA26698.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3EZ2X-ray2.05A/B1-398[»]
3EZ6X-ray2.58A/B1-398[»]
3EZ7X-ray2.92A1-398[»]
ProteinModelPortaliP07620.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP07620. 1 interaction.
MINTiMINT-7290704.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP07620.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR025669. AAA_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13614. AAA_31. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPARA_ECOLX
AccessioniPrimary (citable) accession number: P07620
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: May 11, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Plasmid

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.