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Protein

Cytochrome b-c1 complex subunit 10

Gene

UQCR11

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain.
This protein may be closely linked to the iron-sulfur protein in the complex and function as an iron-sulfur protein binding factor.

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-BTA-611105. Respiratory electron transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b-c1 complex subunit 10
Alternative name(s):
Complex III subunit 10
Complex III subunit XI
Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
Gene namesi
Name:UQCR11
Synonyms:UQCR
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 7

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 5656Cytochrome b-c1 complex subunit 10PRO_0000193559Add
BLAST

Proteomic databases

PaxDbiP07552.
PRIDEiP07552.

Expressioni

Gene expression databases

BgeeiENSBTAG00000008692.

Interactioni

Subunit structurei

The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).

Protein-protein interaction databases

DIPiDIP-61255N.
STRINGi9913.ENSBTAP00000011458.

Structurei

Secondary structure

1
56
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi2 – 54Combined sources
Helixi8 – 3629Combined sources
Helixi39 – 424Combined sources
Beta strandi44 – 474Combined sources
Helixi48 – 514Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1BE3X-ray3.00K1-56[»]
1BGYX-ray3.00K/W1-56[»]
1L0LX-ray2.35K1-56[»]
1L0NX-ray2.60K1-56[»]
1NTKX-ray2.60K1-56[»]
1NTMX-ray2.40K1-56[»]
1NTZX-ray2.60K1-56[»]
1NU1X-ray3.20K1-56[»]
1QCRX-ray2.70K1-45[»]
1SQBX-ray2.69K1-56[»]
1SQPX-ray2.70K1-56[»]
1SQQX-ray3.00K1-56[»]
1SQVX-ray2.85K1-56[»]
1SQXX-ray2.60K1-56[»]
2FYUX-ray2.26K1-56[»]
2YBBelectron microscopy19.00K/k1-56[»]
ProteinModelPortaliP07552.
SMRiP07552. Positions 1-54.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP07552.

Family & Domainsi

Sequence similaritiesi

Belongs to the UQCR11/QCR10 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J5Z0. Eukaryota.
ENOG410XVMI. LUCA.
GeneTreeiENSGT00390000018299.
HOGENOMiHOG000030914.
HOVERGENiHBG105467.
InParanoidiP07552.
KOiK00420.
OMAiGMWGAVG.
OrthoDBiEOG091G1ATB.
TreeFamiTF105034.

Family and domain databases

Gene3Di1.20.5.220. 1 hit.
InterProiIPR029027. Single_a-helix.
IPR015089. UQCR.
[Graphical view]
PANTHERiPTHR15420. PTHR15420. 1 hit.
PfamiPF08997. UCR_6-4kD. 1 hit.
[Graphical view]
SUPFAMiSSF81518. SSF81518. 1 hit.

Sequencei

Sequence statusi: Complete.

P07552-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTRFLGPRY RQLARNWVPT ASLWGAVGAV GLVWATDWRL ILDWVPYING

KFKKDD
Length:56
Mass (Da):6,520
Last modified:December 15, 1998 - v2
Checksum:iA412EA7EB58F45FE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti22 – 221S → Q AA sequence (PubMed:2995132).Curated
Sequence conflicti34 – 341W → S AA sequence (PubMed:2995132).Curated
Sequence conflicti38 – 381W → S AA sequence (PubMed:2995132).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D55637 mRNA. Translation: BAA21747.1.
BC102080 mRNA. Translation: AAI02081.1.
BC126774 mRNA. Translation: AAI26775.1.
PIRiA24096. CBBOC6.
RefSeqiNP_776640.1. NM_174215.2.
UniGeneiBt.5040.

Genome annotation databases

EnsembliENSBTAT00000011458; ENSBTAP00000011458; ENSBTAG00000008692.
GeneIDi281570.
KEGGibta:281570.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D55637 mRNA. Translation: BAA21747.1.
BC102080 mRNA. Translation: AAI02081.1.
BC126774 mRNA. Translation: AAI26775.1.
PIRiA24096. CBBOC6.
RefSeqiNP_776640.1. NM_174215.2.
UniGeneiBt.5040.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1BE3X-ray3.00K1-56[»]
1BGYX-ray3.00K/W1-56[»]
1L0LX-ray2.35K1-56[»]
1L0NX-ray2.60K1-56[»]
1NTKX-ray2.60K1-56[»]
1NTMX-ray2.40K1-56[»]
1NTZX-ray2.60K1-56[»]
1NU1X-ray3.20K1-56[»]
1QCRX-ray2.70K1-45[»]
1SQBX-ray2.69K1-56[»]
1SQPX-ray2.70K1-56[»]
1SQQX-ray3.00K1-56[»]
1SQVX-ray2.85K1-56[»]
1SQXX-ray2.60K1-56[»]
2FYUX-ray2.26K1-56[»]
2YBBelectron microscopy19.00K/k1-56[»]
ProteinModelPortaliP07552.
SMRiP07552. Positions 1-54.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61255N.
STRINGi9913.ENSBTAP00000011458.

Proteomic databases

PaxDbiP07552.
PRIDEiP07552.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000011458; ENSBTAP00000011458; ENSBTAG00000008692.
GeneIDi281570.
KEGGibta:281570.

Organism-specific databases

CTDi10975.

Phylogenomic databases

eggNOGiENOG410J5Z0. Eukaryota.
ENOG410XVMI. LUCA.
GeneTreeiENSGT00390000018299.
HOGENOMiHOG000030914.
HOVERGENiHBG105467.
InParanoidiP07552.
KOiK00420.
OMAiGMWGAVG.
OrthoDBiEOG091G1ATB.
TreeFamiTF105034.

Enzyme and pathway databases

ReactomeiR-BTA-611105. Respiratory electron transport.

Miscellaneous databases

EvolutionaryTraceiP07552.

Gene expression databases

BgeeiENSBTAG00000008692.

Family and domain databases

Gene3Di1.20.5.220. 1 hit.
InterProiIPR029027. Single_a-helix.
IPR015089. UQCR.
[Graphical view]
PANTHERiPTHR15420. PTHR15420. 1 hit.
PfamiPF08997. UCR_6-4kD. 1 hit.
[Graphical view]
SUPFAMiSSF81518. SSF81518. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQCR10_BOVIN
AccessioniPrimary (citable) accession number: P07552
Secondary accession number(s): A1A4P1, O18996, Q3T176
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: December 15, 1998
Last modified: September 7, 2016
This is version 128 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.