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P07540 (LYS_BPPZA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysozyme

EC=3.2.1.17
Alternative name(s):
Endolysin
Late protein gp15
Lysis protein
Muramidase
Gene names
Name:15
OrganismBacillus phage PZA (Bacteriophage PZA) [Complete proteome]
Taxonomic identifier10757 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaePicovirinaePhi29likevirus
Virus hostBacillus subtilis [TaxID: 1423]

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Domain

LysM repeats are thought to be involved in peptidoglycan binding.

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Contains 2 LysM repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258Lysozyme
PRO_0000218106

Regions

Repeat163 – 20745LysM 1
Repeat214 – 25845LysM 2

Sites

Active site151Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
P07540 [UniParc].

Last modified April 1, 1988. Version 1.
Checksum: 1A57FC5334637169

FASTA25828,052
        10         20         30         40         50         60 
MQISQAGINL IKSFEGLQLK AYKAVPTEKH YTIGYGHYGS DVSPRQVITA KQAEDMLRDD 

        70         80         90        100        110        120 
VQAFVDGVNK ALKVSVTQNQ FDALVSFAYN VGLGAFRSSS LLEYLNEGRT ALAAAEFPRW 

       130        140        150        160        170        180 
NKSGGKVYQG LVNRRAQEQA LFNSGTPKNV SRGTSSSKVT PKYKVKSGDN LTKIAKKHNT 

       190        200        210        220        230        240 
TVATLLKLNP SIKDPNMIRV GQTINVTGSG GKTHKVKSGD TLSKIAVDNK TTVSRLMSLN 

       250 
PEITNPNHIK VGQTIRLS 

« Hide

References

[1]"Nucleotide sequence of the late region of Bacillus subtilis phage PZA, a close relative of phi 29."
Paces V., Vlcek C., Urbanek P.
Gene 44:107-114(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M11813 Genomic DNA. Translation: AAA88492.1.
PIRWMBP15. A26215.

3D structure databases

ProteinModelPortalP07540.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyCBM50. Carbohydrate-Binding Module Family 50.
GH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.530.40. 1 hit.
3.10.350.10. 2 hits.
InterProIPR002196. Glyco_hydro_24.
IPR018392. LysM_dom.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamPF01476. LysM. 2 hits.
PF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SMARTSM00257. LysM. 2 hits.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
SSF54106. SSF54106. 2 hits.
ProtoNetSearch...

Entry information

Entry nameLYS_BPPZA
AccessionPrimary (citable) accession number: P07540
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries