Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P07528

- XYNA_BACHD

UniProt

P07528 - XYNA_BACHD

Protein

Endo-1,4-beta-xylanase A

Gene

xynA

Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 Apr 1988)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

    pH dependencei

    Active over a very broad pH range.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei195 – 1951Proton donorBy similarity
    Active sitei301 – 3011NucleophilePROSITE-ProRule annotation

    GO - Molecular functioni

    1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC

    GO - Biological processi

    1. xylan catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

    Enzyme and pathway databases

    BioCyciBHAL272558:GJC5-2204-MONOMER.
    UniPathwayiUPA00114.

    Protein family/group databases

    CAZyiGH10. Glycoside Hydrolase Family 10.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endo-1,4-beta-xylanase A (EC:3.2.1.8)
    Short name:
    Xylanase A
    Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase A
    Gene namesi
    Name:xynA
    Ordered Locus Names:BH2120
    OrganismiBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
    Taxonomic identifieri272558 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001258: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 28281 PublicationAdd
    BLAST
    Chaini29 – 396368Endo-1,4-beta-xylanase APRO_0000007967Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272558.BH2120.

    Structurei

    Secondary structure

    1
    396
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi51 – 533
    Helixi57 – 604
    Turni61 – 644
    Beta strandi66 – 716
    Helixi73 – 753
    Helixi78 – 8710
    Beta strandi89 – 957
    Helixi99 – 1024
    Helixi112 – 12413
    Beta strandi127 – 1304
    Beta strandi133 – 1386
    Helixi141 – 1444
    Helixi152 – 1543
    Helixi158 – 18326
    Turni184 – 1863
    Beta strandi188 – 1958
    Beta strandi201 – 2033
    Helixi207 – 2126
    Helixi215 – 22814
    Beta strandi234 – 2396
    Helixi244 – 25916
    Beta strandi266 – 2694
    Beta strandi272 – 2765
    Helixi280 – 29112
    Turni292 – 2943
    Beta strandi296 – 30712
    Helixi318 – 3203
    Helixi323 – 34220
    Helixi344 – 3463
    Beta strandi347 – 35610
    Helixi361 – 3699
    Turni370 – 3723
    Beta strandi379 – 3813
    Beta strandi385 – 3873
    Helixi389 – 3957

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2UWFX-ray2.10A48-396[»]
    ProteinModelPortaliP07528.
    SMRiP07528. Positions 47-396.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP07528.

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG3693.
    HOGENOMiHOG000019847.
    KOiK01181.
    OMAiGAAVEPY.
    OrthoDBiEOG6B363F.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001000. Glyco_hydro_10.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF00331. Glyco_hydro_10. 1 hit.
    [Graphical view]
    PRINTSiPR00134. GLHYDRLASE10.
    SMARTiSM00633. Glyco_10. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.
    PROSITEiPS00591. GLYCOSYL_HYDROL_F10. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P07528-1 [UniParc]FASTAAdd to Basket

    « Hide

    MITLFRKPFV AGLAISLLVG GGIGNVAAAQ GGPPKSGVFG ENEKRNDQPF    50
    AWQVASLSER YQEQFDIGAA VEPYQLEGRQ AQILKHHYNS LVAENAMKPE 100
    SLQPREGEWN WEGADKIVEF ARKHNMELRF HTLVWHSQVP EWFFIDEDGN 150
    RMVDETDPDK REANKQLLLE RMENHIKTVV ERYKDDVTSW DVVNEVIDDG 200
    GGLRESEWYQ ITGTDYIKVA FETARKYGGE EAKLYINDYN TEVPSKRDDL 250
    YNLVKDLLEQ GVPIDGVGHQ SHIQIGWPSI EDTRASFEKF TSLGLDNQVT 300
    ELDMSLYGWP PTGAYTSYDD IPAELLQAQA DRYDQLFELY EELAADISSV 350
    TFWGIADNHT WLDGRAREYN NGVGIDAPFV FDHNYRVKPA YWRIID 396
    Length:396
    Mass (Da):45,294
    Last modified:April 1, 1988 - v1
    Checksum:i29C1F46BE00E180C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D00087 Genomic DNA. Translation: BAA00055.1.
    BA000004 Genomic DNA. Translation: BAB05839.1.
    PIRiH83914.
    JD0003.
    RefSeqiNP_242986.1. NC_002570.2.

    Genome annotation databases

    EnsemblBacteriaiBAB05839; BAB05839; BAB05839.
    GeneIDi891394.
    KEGGibha:BH2120.
    PATRICi18941396. VBIBacHal18977_2211.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D00087 Genomic DNA. Translation: BAA00055.1 .
    BA000004 Genomic DNA. Translation: BAB05839.1 .
    PIRi H83914.
    JD0003.
    RefSeqi NP_242986.1. NC_002570.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2UWF X-ray 2.10 A 48-396 [» ]
    ProteinModelPortali P07528.
    SMRi P07528. Positions 47-396.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272558.BH2120.

    Protein family/group databases

    CAZyi GH10. Glycoside Hydrolase Family 10.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB05839 ; BAB05839 ; BAB05839 .
    GeneIDi 891394.
    KEGGi bha:BH2120.
    PATRICi 18941396. VBIBacHal18977_2211.

    Phylogenomic databases

    eggNOGi COG3693.
    HOGENOMi HOG000019847.
    KOi K01181.
    OMAi GAAVEPY.
    OrthoDBi EOG6B363F.

    Enzyme and pathway databases

    UniPathwayi UPA00114 .
    BioCyci BHAL272558:GJC5-2204-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P07528.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001000. Glyco_hydro_10.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF00331. Glyco_hydro_10. 1 hit.
    [Graphical view ]
    PRINTSi PR00134. GLHYDRLASE10.
    SMARTi SM00633. Glyco_10. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    PROSITEi PS00591. GLYCOSYL_HYDROL_F10. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the xylanase A gene of alkalophilic Bacillus sp. strain C-125."
      Hamamoto T., Honda H., Kudo T., Horikoshi K.
      Agric. Biol. Chem. 51:953-955(1987)
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF N-TERMINUS.
      Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
    2. "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
      Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
      Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

    Entry informationi

    Entry nameiXYNA_BACHD
    AccessioniPrimary (citable) accession number: P07528
    Secondary accession number(s): Q9JPV5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1988
    Last sequence update: April 1, 1988
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3