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P07528

- XYNA_BACHD

UniProt

P07528 - XYNA_BACHD

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Protein
Endo-1,4-beta-xylanase A
Gene
xynA, BH2120
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

pH dependencei

Active over a very broad pH range.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei195 – 1951Proton donor By similarity
Active sitei301 – 3011Nucleophile By similarity

GO - Molecular functioni

  1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC

GO - Biological processi

  1. xylan catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

BioCyciBHAL272558:GJC5-2204-MONOMER.
UniPathwayiUPA00114.

Protein family/group databases

CAZyiGH10. Glycoside Hydrolase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanase A (EC:3.2.1.8)
Short name:
Xylanase A
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase A
Gene namesi
Name:xynA
Ordered Locus Names:BH2120
OrganismiBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Taxonomic identifieri272558 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001258: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 28281 Publication
Add
BLAST
Chaini29 – 396368Endo-1,4-beta-xylanase A
PRO_0000007967Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272558.BH2120.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi51 – 533
Helixi57 – 604
Turni61 – 644
Beta strandi66 – 716
Helixi73 – 753
Helixi78 – 8710
Beta strandi89 – 957
Helixi99 – 1024
Helixi112 – 12413
Beta strandi127 – 1304
Beta strandi133 – 1386
Helixi141 – 1444
Helixi152 – 1543
Helixi158 – 18326
Turni184 – 1863
Beta strandi188 – 1958
Beta strandi201 – 2033
Helixi207 – 2126
Helixi215 – 22814
Beta strandi234 – 2396
Helixi244 – 25916
Beta strandi266 – 2694
Beta strandi272 – 2765
Helixi280 – 29112
Turni292 – 2943
Beta strandi296 – 30712
Helixi318 – 3203
Helixi323 – 34220
Helixi344 – 3463
Beta strandi347 – 35610
Helixi361 – 3699
Turni370 – 3723
Beta strandi379 – 3813
Beta strandi385 – 3873
Helixi389 – 3957

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2UWFX-ray2.10A48-396[»]
ProteinModelPortaliP07528.
SMRiP07528. Positions 47-396.

Miscellaneous databases

EvolutionaryTraceiP07528.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG3693.
HOGENOMiHOG000019847.
KOiK01181.
OMAiGAAVEPY.
OrthoDBiEOG6B363F.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P07528-1 [UniParc]FASTAAdd to Basket

« Hide

MITLFRKPFV AGLAISLLVG GGIGNVAAAQ GGPPKSGVFG ENEKRNDQPF    50
AWQVASLSER YQEQFDIGAA VEPYQLEGRQ AQILKHHYNS LVAENAMKPE 100
SLQPREGEWN WEGADKIVEF ARKHNMELRF HTLVWHSQVP EWFFIDEDGN 150
RMVDETDPDK REANKQLLLE RMENHIKTVV ERYKDDVTSW DVVNEVIDDG 200
GGLRESEWYQ ITGTDYIKVA FETARKYGGE EAKLYINDYN TEVPSKRDDL 250
YNLVKDLLEQ GVPIDGVGHQ SHIQIGWPSI EDTRASFEKF TSLGLDNQVT 300
ELDMSLYGWP PTGAYTSYDD IPAELLQAQA DRYDQLFELY EELAADISSV 350
TFWGIADNHT WLDGRAREYN NGVGIDAPFV FDHNYRVKPA YWRIID 396
Length:396
Mass (Da):45,294
Last modified:April 1, 1988 - v1
Checksum:i29C1F46BE00E180C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00087 Genomic DNA. Translation: BAA00055.1.
BA000004 Genomic DNA. Translation: BAB05839.1.
PIRiH83914.
JD0003.
RefSeqiNP_242986.1. NC_002570.2.

Genome annotation databases

EnsemblBacteriaiBAB05839; BAB05839; BAB05839.
GeneIDi891394.
KEGGibha:BH2120.
PATRICi18941396. VBIBacHal18977_2211.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00087 Genomic DNA. Translation: BAA00055.1 .
BA000004 Genomic DNA. Translation: BAB05839.1 .
PIRi H83914.
JD0003.
RefSeqi NP_242986.1. NC_002570.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2UWF X-ray 2.10 A 48-396 [» ]
ProteinModelPortali P07528.
SMRi P07528. Positions 47-396.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272558.BH2120.

Protein family/group databases

CAZyi GH10. Glycoside Hydrolase Family 10.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB05839 ; BAB05839 ; BAB05839 .
GeneIDi 891394.
KEGGi bha:BH2120.
PATRICi 18941396. VBIBacHal18977_2211.

Phylogenomic databases

eggNOGi COG3693.
HOGENOMi HOG000019847.
KOi K01181.
OMAi GAAVEPY.
OrthoDBi EOG6B363F.

Enzyme and pathway databases

UniPathwayi UPA00114 .
BioCyci BHAL272558:GJC5-2204-MONOMER.

Miscellaneous databases

EvolutionaryTracei P07528.

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF00331. Glyco_hydro_10. 1 hit.
[Graphical view ]
PRINTSi PR00134. GLHYDRLASE10.
SMARTi SM00633. Glyco_10. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 1 hit.
PROSITEi PS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of the xylanase A gene of alkalophilic Bacillus sp. strain C-125."
    Hamamoto T., Honda H., Kudo T., Horikoshi K.
    Agric. Biol. Chem. 51:953-955(1987)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF N-TERMINUS.
    Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
  2. "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis."
    Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.
    Nucleic Acids Res. 28:4317-4331(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Entry informationi

Entry nameiXYNA_BACHD
AccessioniPrimary (citable) accession number: P07528
Secondary accession number(s): Q9JPV5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: May 14, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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