Endo-1,4-beta-xylanase A precursor

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Reviewed, UniProtKB/Swiss-Prot P07528 (XYNA_BACHD)

Last modified June 16, 2009. Version 72. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase A
      Short name=Xylanase A
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase A

Gene names

Name:	xynA
Ordered Locus Names:	BH2120

Organism

Bacillus halodurans [Complete proteome] [HAMAP]

Taxonomic identifier

86665 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

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Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

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General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Biophysicochemical properties	pH dependence: Active over a very broad pH range.

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Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
Technical term	3D-structure Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

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Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 28

Chain

29 – 396

368

Endo-1,4-beta-xylanase A

PRO_0000007967

Sites

Active site

195

Proton donor By similarity

Active site

301

Nucleophile By similarity

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Sequences

Sequence

Length

Mass (Da)

Tools

P07528-1 [UniParc].

Last modified April 1, 1988. Version 1.
Checksum: 29C1F46BE00E180C
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FASTA

396

45,294

        10         20         30         40         50         60 
MITLFRKPFV AGLAISLLVG GGIGNVAAAQ GGPPKSGVFG ENEKRNDQPF AWQVASLSER 

        70         80         90        100        110        120 
YQEQFDIGAA VEPYQLEGRQ AQILKHHYNS LVAENAMKPE SLQPREGEWN WEGADKIVEF 

       130        140        150        160        170        180 
ARKHNMELRF HTLVWHSQVP EWFFIDEDGN RMVDETDPDK REANKQLLLE RMENHIKTVV 

       190        200        210        220        230        240 
ERYKDDVTSW DVVNEVIDDG GGLRESEWYQ ITGTDYIKVA FETARKYGGE EAKLYINDYN 

       250        260        270        280        290        300 
TEVPSKRDDL YNLVKDLLEQ GVPIDGVGHQ SHIQIGWPSI EDTRASFEKF TSLGLDNQVT 

       310        320        330        340        350        360 
ELDMSLYGWP PTGAYTSYDD IPAELLQAQA DRYDQLFELY EELAADISSV TFWGIADNHT 

       370        380        390 
WLDGRAREYN NGVGIDAPFV FDHNYRVKPA YWRIID

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of the xylanase A gene of alkalophilic Bacillus sp. strain C-125." Hamamoto T., Honda H., Kudo T., Horikoshi K. Agric. Biol. Chem. 51:953-955(1987) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-11. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.
[2]	"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153.

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Cross-references

Sequence databases

D00087 Genomic DNA. Translation: BAA00055.1.
BA000004 Genomic DNA. Translation: BAB05839.1.

PIR

H83914.
JD0003.

RefSeq

NP_242986.1.

3D structure databases

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2UWF	X-ray	2.10	A	47-396	[»]

SMR

P07528. Positions 48-396.

ModBase

Search...

Protein family/group databases

CAZy

GH10. Glycoside Hydrolase Family 10.

Genome annotation databases

GeneID

891394.

GenomeReviews

Gene locus BH2120 in contig BA000004_GR.

KEGG

bha:BH2120.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

P07528.

OMA

P07528. GAAVEPY.

Enzyme and pathway databases

BioCyc

BHAL272558:BH2120-MON.

BRENDA

3.2.1.8. 191865.

Family and domain databases

InterPro

IPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_sg_catalytic.
[Graphical view]

Gene3D

G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.

Pfam

PF00331. Glyco_hydro_10. 1 hit.
[Graphical view]

PRINTS

PR00134. GLHYDRLASE10.

SMART

SM00633. Glyco_10. 1 hit.
[Graphical view]

PROSITE

PS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view]

ProtoNet

Search...

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Entry information

Entry name

XYNA_BACHD

Accession

Primary (citable) accession number: P07528
Secondary accession number(s): Q9JPV5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1988
Last sequence update:	April 1, 1988
Last modified:	June 16, 2009
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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