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P07446 (RNPB_PENBR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Guanyl-specific ribonuclease Pb1

Short name=RNase Pb1
EC=3.1.27.3
OrganismPenicillium brevicompactum
Taxonomic identifier5074 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicillium

Protein attributes

Sequence length102 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.

Sequence similarities

Belongs to the ribonuclease N1/T1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 102102Guanyl-specific ribonuclease Pb1
PRO_0000137372

Sites

Active site381 By similarity
Active site561Proton acceptor By similarity
Active site901Proton donor By similarity

Amino acid modifications

Disulfide bond2 ↔ 10 Ref.1
Disulfide bond6 ↔ 101 Ref.1

Sequences

Sequence LengthMass (Da)Tools
P07446 [UniParc].

Last modified April 1, 1988. Version 1.
Checksum: 1D8AA5602C93DEEE

FASTA10210,803
        10         20         30         40         50         60 
ACAATCGTVC YTSSAISSAQ AAGYNLYSTN DDVSNYPHEY HNYEGFDFPV SGTYYEFPIL 

        70         80         90        100 
KSGKVYTGSS PGADRVIFND DDELAGVITH TGASGNNFVA CT 

« Hide

References

[1]"Analysis of the guanyl-specific ribonuclease structures in fungi: determination of the amino acid sequence and prediction of the secondary ribonuclease structure in Penicillium brevicompactum."
Shlyapnikov S.V., Yakovlev G.I., Kulikov V.A.
Dokl. Akad. Nauk SSSR 281:226-229(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE, DISULFIDE BONDS.

Cross-references

Sequence databases

PIRNRPLTB. A23350.

3D structure databases

ProteinModelPortalP07446.
SMRP07446. Positions 1-102.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.10.450.30. 1 hit.
InterProIPR000026. Gua-sp_ribonuclease_N1/T1.
IPR016191. Ribonuclease/ribotoxin.
[Graphical view]
PfamPF00545. Ribonuclease. 1 hit.
[Graphical view]
SUPFAMSSF53933. SSF53933. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNPB_PENBR
AccessionPrimary (citable) accession number: P07446
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families