Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Aspartate ammonia-lyase

Gene

aspA

Organism
Pseudomonas fluorescens
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate = fumarate + NH3.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei109SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate ammonia-lyase (EC:4.3.1.1)
Short name:
Aspartase
Gene namesi
Name:aspA
OrganismiPseudomonas fluorescens
Taxonomic identifieri294 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001613441 – 478Aspartate ammonia-lyaseAdd BLAST478

Proteomic databases

PRIDEiP07346.

Interactioni

Subunit structurei

Homotetramer.

Protein-protein interaction databases

STRINGi1114970.PSF113_0104.

Structurei

3D structure databases

ProteinModelPortaliP07346.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni148 – 150Substrate bindingBy similarity3

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P07346-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISVMSSAAS FRTEKDLLGV LEVPAQAYYG IQTLRAVNNF RLSGVPISHY
60 70 80 90 100
PKLVVGLAMV KQAAADANRE LGQLSERKHA AISEACARLI RGDFHEEFVV
110 120 130 140 150
DMIQGGAGTS TNMNANEVIA NIALEAMGHQ KGEYQYLHPN NDVNMAQSTN
160 170 180 190 200
DAYPTAIRLG LLLGHDALLA SLDSLIQAFA AKGAEFSHVL KMGRTQLQDA
210 220 230 240 250
VPMTLGQEFR AFATTLGEDL ARLKTLAPEL LTEVNLGGTA IGTGINADPR
260 270 280 290 300
YQALAVQRLA TISGQPLVPA ADLIEATSDM GAFVLFSGML KRTAVKLSKI
310 320 330 340 350
CNDLRLLSSG PRTGINEINL PARQPGSSIM PGKVNPVIPE AVNQVAFQVI
360 370 380 390 400
GNDLALTMAA EGGQLQLNVM EPLIAFKIFD SIRLLQRAMD MLREHCIVGI
410 420 430 440 450
TANEARCREL VEHSIGLVTA LNPYIGYENA TRIARIALES GRGVLELVRE
460 470
EGLLDDAMLD DILRPENMIA PRLVPLKA
Length:478
Mass (Da):51,508
Last modified:April 1, 1988 - v1
Checksum:iE7903CC4DA7C99C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D00100 Genomic DNA. Translation: BAA00062.1.
X04441 Genomic DNA. Translation: CAA28037.1.
PIRiA24874. UFPSDF.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D00100 Genomic DNA. Translation: BAA00062.1.
X04441 Genomic DNA. Translation: CAA28037.1.
PIRiA24874. UFPSDF.

3D structure databases

ProteinModelPortaliP07346.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1114970.PSF113_0104.

Proteomic databases

PRIDEiP07346.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiASPA_PSEFL
AccessioniPrimary (citable) accession number: P07346
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: November 2, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.